抗免疫的

The invention relates to the isolation and preparation of an active fraction from plant Cuminum cyminum, its further purification and standardization as chemically defined entity with their intended use as drug bioavailability enhancer for the drugs belonging to therapeutic categories such as antimicrobial, antifungal, anti-viral, antitubercular, antileprosy, anti-inflammatory, antiarthritic, cardiovascular, antihistaminics, respiratory distress relieving drugs, immunosuppressants, anti-ulcerogenic, anti-cancer, CNS drugs, corticosteroids, nutraceuticals in compositions to be administered orally/parenterally, topically, inhalations, rectally, vaginally in human beings and/or veterinary conditions.

本发明涉及植物孜然芹中的一种活性级分的分离和制备，进一步的纯化以及它作为化学确定实体的标准化，和它作为治疗类药物的生物利用率增强剂的特定用途，这类药物包括如抗微生物剂、抗真菌剂、抗病毒剂、抗结核药、抗麻风病药、抗炎药、抗关节炎药、心血管类药、抗组胺药、呼吸窘迫缓解药、免疫抑制剂、抗溃疡药、抗癌药、CNS药、皮质甾类药、营养制品，它们以组合物的形式通过口服/肠胃外，局部，吸入直肠，阴道施用于人和/或兽医学病症中。

Methods Highly purified HCV Core, NS3, NS4, NS5 proteins were immobilized on solid matrix by biochip arrayer, the protein chip was used to detect the corresponding antibodies in human serum by chemiluminescent immunoassays.

利用生物芯片技术和化学发光技术将高度纯化的抗原HCV Core、NS3、NS4、NS5以特定微阵列固定在固相载体上，用化学发光免疫法检测抗HCV Core、抗HCV NS3、抗HCV NS4和抗HCV NS5。

At the same time,its new bio-effects on the heart-blood vessel system,antimicrobial,immunological regulation,anti-inflammation and antivirus have been identified clinically for a long time.

近年来，大量的研究证实AT具有抗肿瘤、抗静脉机能不全、抗溃疡、促创伤愈合、抗抑郁以及恢复神经功能等多种药理活性，同时还显现出在心血管、免疫调节、抗炎、抗病毒等方面的药理作用。

The methods of TAS-ELISA and DAS-ELISA were established to detect Cymbidium mosaic virus and Odontoglossum ringspot virus, respectively. The experiment was carried out with 139 orchidaceous samples and 8 liliaceous samples in Zhejiang province.

建立了三抗夹心酶联免疫吸附法检测建兰花叶病毒(Cymbidium mosaic virus， CymMV)和双抗夹心酶联免疫吸附法检测齿兰环斑病毒(Odontoglossum ringspot virus， ORSV)的方法。

RESULTS:After pinealectomized mice was irradiated WBI with 75 mGy X-rays,we found levels of plasma corticosterone increased obviously,and the effects of the proliferative reaction of splenocytes to ConA and spontaneous proliferation of thymocytes was found to be decrease. But injecting melatonin into pinealectomized mice or putting melatonin in the cultured cell,its immune functions might renew the enhancement.CONCLUSION:Melatonin of pineal gland might regulate the immunoenhancement induced by low dose radiation.MeSH Pineal body; Melatonin; Radiation; Corticosterone; Immunity,cellular

低剂量辐射(low dose radiation，LDR)全身照射(whole body irradiation，WBI)可引起免疫系统的兴奋效应，主要表现在以T淋巴细胞功能激活为主的细胞免疫和体液免疫功能的增强并可提高机体的抗瘤作用［4，5］，在LDR诱发免疫功能增强的同时伴有下丘脑-垂体-肾上腺皮质系统功能下调等神经内分泌功能的改变，神经内分泌对免疫系统的调节可能是LDR免疫兴奋效应发生的必要条件，松果腺MLT与辐射免疫兴奋效应的关系值得研究。

In order to establish a sensitive immuno-PCR assay for detecting serai anti-P53antibodies, investigate the relation of anti-P53 antibodies in patients with breast carcinoma to P53 protein expressions in tissue and clinical significances and afford a practical tool in diagnosis of breast carcinoma clinically. SaHIgG was coupled to PNCa DNA by chemical cross-linker PEI and SaHIgG-DNA probe was constructed.

本研究建立了血清抗P53蛋白抗体免疫聚合酶链反应(Immuno-polymerase chain reaction，免疫PCR)检测方法，探讨了乳腺癌患者血清中抗P53蛋白抗体与组织中P53蛋白表达之间的关系及临床意义，旨在为临床乳腺癌P53蛋白检测提供实用的替代工具。

The former one appears in stimulation of worm activity, spasmodic contraction of worm musculatures and severe damage to the tegument, which results in hepatic shift of schistosomes, influence on the nutrition absorption, excretion/secretion and defense function of the tegument, followed by the secondary interference with the worm metabolism.

前者表现为虫体活动兴奋，肌肉挛缩和皮层严重受损，从而导致虫的肝移，影响虫的体表营养吸收、排泌和防御功能以及继发的代谢紊乱；后者因皮层的损害和剥落破坏了虫体在宿主体内存活的伴随免疫机制，其体表抗原的显露为宿主抗血吸虫特异性抗体的免疫攻击提供了靶部位，即吡喹酮的抗血吸虫作用是免疫依赖的。

Allium(Allium sativum L.)is a kind of buld which belongs to liliaceae.It has some pharmacological actions,such as antibiosis antivirus antioxygenation and antitumor,which has many different mechanism.And suggested that allicin has wide foreground in antitumor.

大蒜是百合科属植物的鳞茎，具有多种药理作用，如抗菌、抗病毒、抗氧化、免疫以及抗肿瘤作用，其中抗肿瘤作用的机制不尽相同，其在抗肿瘤方面有着广阔的前景。

Methods The polyclonal antibody was obtained by immunizing rabbits with the crude extracts of Humulus pollen It was primarily identified using indirect ELISA and double immuno-diffusion.

用葎草花粉变应原浸液免疫兔，获得高效价抗葎草花粉蛋白抗血清，应用琼脂免疫双扩散、ELISA法以及Western blotting鉴定产生的抗体。

METHODS: Female BALB/c mice were treated with CCK-8 and keyhole limpet haemocyanin, splenocytes were acquired and incubated in vitro with KLH restimulation, the productions of Th1 cytokines, interferon-γ, interleukin-2 and Th2 cytokines, IL-4, IL-5 in cell culture supernatants were detected by enzyme-linked immunosorbnent assay. The mRNA expressions of IFN-γ, IL-2, IL-4 and IL-5 in splenocytes were detected by reverse transcription-polymerase chain reaction. The levels of Th1 antibody IgG2a and Th2 antibodies IgG1 in serum were also detected by ELISA.

给予BALB/c小鼠钥孔戚血蓝蛋白免疫同时体内给予不同剂量的CCK-8，酶联免疫吸附试验检测其脾细胞培养上清中Th1型细胞因子γ-干扰素、白细胞介素-2（IL-2）和Th2型细胞因子白细胞介素-4（IL-4）、白细胞介素-5（IL-5）水平，逆转录聚合酶链式反应法检测脾细胞中IFN-γ、IL-2、IL-4、IL-5 mRNA表达；ELISA法检测血清中Th1型抗KLH抗体IgG2a和Th2型抗KLH抗体IgG1水平。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。