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Objective: To explore the effects of heroin dependence on the expression of somatostatin, interleukin-2 (IL-2) positive cells in gastric antrum of rats.

目的:探讨海洛因依赖对大鼠胃窦生长抑素、白细胞介素2(IL-2)阳性细胞表达的影响。

Objective: To investigate the possibility of pathologic scars treated in endostatin , by observing the effects of endothelial cell and neogenesis capillary of pathologic scars treated in endostatin , through establishing models of hyperplastic scar in rabbit ear and injecting Endostatin .

目的:建立兔耳增生性瘢痕的动物模型,并采用内皮抑素局部在体干预,观察其对病理性瘢痕新生毛细血管及血管内皮细胞的影响,以探讨内皮抑素防治病理性瘢痕的可行性。

The different effectiveness of controlling esophageal variceal bleeding of somatostatin, octreotide and pituitrin combined with nitroglycerin was investigated and compared.

摘 要:比较了生长抑素14肽施他宁和8肽善得定及垂体后叶素与硝酸甘油联用对食管静脉曲张破裂出血的止血疗效。

The transter and expression of endostatin gene was analyzed by PCR, the effects of inhibition on proliferation of endothelial cell by endostatin in vitro by MTT method, and the effects on the growth of LoVo、 SGC-7901 in vitro was surveyed, and the growth of expressing endostatin LoVo、SGC-7901 cell line_in subcutaneously of nude mice was also measured.

用MTT法检测内皮抑素对内皮细胞体外增殖的抑制作用,并观察其对LoVo细胞和SGC-7901细胞体外生长的影响,观察表达内皮抑素基因的LoVo和SGC-7901细胞在裸鼠皮下种植的生长。

The results obtained are as follows:(1) intrarenal artery injection of capsaicin (20, 40, and 60 nmol/kg) increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2) pretreatment with ruthenium red (40 mmol/kg), a capsaicin receptor antagonist, completely abolished the effect of capsaicin; and (3) pretreatment with a nitric oxide synthase inhibitor L-NAME ( N6-nitro-L-arginine methylester, 0.1 mmol/kg), significantly enhanced the ARNA response to capsaicin.

结果表明:(1)肾动脉内注射辣椒素20、40和60nmol/kg可呈剂量依赖性地兴奋肾传入纤维的活动,而动脉血压不变;(2)静脉内预先应用辣椒素受体阻断剂钌红(40 mmok/kg),可完全阻断辣椒素对肾传入纤维的兴奋作用。(3)静脉内预先注射一氧化氮合酶抑制剂L-NAME(0.1 mmok/kg),能延长并增强肾传入神经对辣椒素的反应。

Recombinant hANG had no effect on the expression of VEGF and bFGF in both SMCC-7221 cells and HUVEC cells, suggested that hANG exerted its antiangiogenic role not through the inhibition of the autosecretion and parasecretion of angiogenic stimulatory factors VEGF and bFGF.

重组人血管抑素对SMMC-7721肝癌细胞及HUVEC细胞中两种血管生长刺激因子VEGF和bFGF的表达没有影响,提示血管抑素对肿瘤血管生长的抑制作用不是通过抑制血管生长刺激因子的自分泌和旁分泌来实现的。

Recombinant endostatin is a specific inhibitor of chick chorioallantoic membrane angiogenesis and human vitelline vein endothelial cell ECV-304 proliferation. The recombinant endostatin regressed established syngeneic B16 melanoma tumor in mice.

重组内皮抑素能够抑制鸡胚尿囊膜血管生成和人脐静脉内皮细胞ECV-304的增殖,在小鼠体内实验中对黑色素瘤产生良好的抑瘤效果(P<0.01)。

DISCUSSION: In obese individuals, somatostatin analog significantly reduced postprandial sensations after a satiating meal without altering maximum tolerated meal volume or postnutrient gastric volume, suggesting an effect on upper gut sensation.

讨论:对于肥胖的个体,生长抑素类似物明显减少饱食后进餐后的感觉,但并没有改变最大进餐耐受容积或营养后的胃容积,提示生长抑素类似物影响上消化道的感觉。

Most 5-HT cells appeared in the base part of gland in the rat, while in the human they were mainly located in the intercellular substance and a few scatted in the glandular epithelium.

方法采用免疫细胞化学方法,检测人和大鼠胃窦部粘膜内生长抑素细胞、胃泌素细胞、5-羟色胺细胞(5-HT细胞)、嗜铬粒素A细胞的分布。

The above results suggest that the inhibitory effect of centrally administrated HA on gastric acid secretion is mediated by vagi, acetylcholine M receptor and somatostatin.

结果提示:HA的中枢抑酸效应由迷走神经传出,可能通过乙酰胆碱M受体及引起生长抑素释放实现。

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