抑素的

In the last ten years, Chinese scientists have found that angustmycin A had biological activities of cytokinin.

狭霉素A是一种特异的鸟嘌呤核苷酸合成酶抑制剂，在实验室中广泛应用。

Evidence Synthesis: The extrapancreatic actions of GLP-1 include inhibition of gastric emptying and gastric acid secretion, thereby fulfilling the definition of GLP-1 as an enterogastrone.

数据综合： GLP-1的胰腺外功能包括抑制胃排空和胃酸分泌，证实了GLP-1是一种肠抑胃素。

Expression of mutant tumor suppressor gene p53 in egg-type chicken with avian leukosis subgroup J was detected to study cancericidally molecular mechanism of ALV-J. Using immunohistochemistry method of strep avidin-biotin complex, many organs of illed egg-type chickens, involved liver, kidney, ventriculus glandularis, tumor, heart, pancreas, bone marrow, spleen, oviduct, lung, duodenum, thymus and bursa of fabricius were studied.

为了探讨J亚群禽白血病病毒的致癌分子机理，观察蛋用型鸡发生J亚群禽白血病时p53抑癌基因在各脏器中的表达，应用链霉亲和素-生物素-过氧化物酶复合物免疫组化法，研究了蛋用型鸡J亚群禽白血病自然病例的肝脏、肾脏、腺胃、肿瘤、输卵管、心脏、胰脏、骨髓、脾脏、肺脏、十二指肠、胸腺和法氏囊。

Alpha-1 antitrypsin is the most abundant circulating protease inhibitor in the body, Dr. Lomas said. Its most common deficiency mutation is the Z allele, where the amino acid lysine is exchanged for glutamic acid at position 342 in the polypeptide chain (Glu342Lys). About 1 in 1700 whites of northern European descent are homozygotes for this mutation and thus have plasma antitrypsin levels that are 10% to 15% below normal, he said.

Lomas博士表示，甲一型抗胰蛋白酵素是身体内最充分的循环蛋白酶抑制剂，最常见的缺损突变在Z对偶基因，该处的胺基酸 lysine与麸氨酸在多胜肽链的第342位置交换(Glu342Lys)；北欧血统白人每1，700人有1人是此一突变的同合子，因此血浆抗胰蛋白酵素值比正常低10%到15%。

METHODS:We recorded the cardiogram by perfusing garlicin injection and garlic preparation to the isolated heart of rabbits by Langendorff method,examined the minimum dose of asystole. RESULTS:The minimum fungistatic concentration of garlicin injection was 3～6.2 times lower than that of garlic preparation.

采用Langendorf法对兔离体心脏分别灌流大蒜素注射液、大蒜注射液、大蒜实验液，分别记录心搏图，求出致心脏停搏的最小剂量，结果：大蒜素注射液的抑菌浓度为大蒜实验液的1／6.2～1／3，而致心脏停搏的最小浓度分别为0.1736u／ml和3.919u／ml。

METHODS:We recorded the cardiogram by perfusing garlicin injection and garlic preparation to the isolated heart of rabbits by Langendorff method,examined the minimum dose of asystole. RESULTS:The minimum fungistatic concentration of garlicin injection was 3～6.2 times lower than that of garlic preparation. The minimum dose of garlic preparation is 0.1736 u/ml, and that of garlicin injection is 3.919 u/ml.

采用Langendorff法对兔离体心脏分别灌流大蒜素注射液、大蒜注射液、大蒜实验液，分别记录心搏图，求出致心脏停搏的最小剂量，结果：大蒜素注射液的抑菌浓度为大蒜实验液的1/6.2～1/3，而致心脏停搏的最小浓度分别为0.1736 u/ml和3.919 u/ml。

Validamycins have been one of the most popular and economical biopesticides in China, by microbial transformation of which validoxylamine A and valienamine can be produced. Validoxylamine A has strong inhibition on trehalase and it is a new promising insecticide. Valienamine demonstrates strong glucosidase inhibitory activity, which can also be used as intermediate in the synthesis of medicines for diabetes.

井冈霉素目前已成为我国最经济最受欢迎的生物农药之一，用微生物转化法分解井冈霉素可以得到井冈霉亚基胺A和井冈胺，前者对海藻糖酶有强烈的抑制作用，有望开发成为新型生物杀虫剂，而后者是一种糖苷酶抑制剂，也可作为合成降糖药的原料。

METHODS: Collaborative meta-analyses were undertaken of 194 unconfounded randomised trials of adjuvant chemotherapy or hormonal therapy that began by 1995. Many trials involved CMF (cyclophosphamide, methotrexate, fluorouracil), anthracycline-based combinations such as FAC (fluorouracil, doxorubicin, cyclophosphamide) or FEC (fluorouracil, epirubicin, cyclophosphamide), tamoxifen, or ovarian suppression: none involved taxanes, trastuzumab, raloxifene, or modern aromatase inhibitors.

对194个开始于1995年的关于辅助化疗或激素治疗的随机试验进行meta分析，许多试验包含了CMF(环磷酰胺、氨甲喋呤、氟尿嘧啶)，蒽环药物为基础的联合化疗比如FAC(氟尿嘧啶、阿霉素、环磷酰胺)或FEC（氟尿嘧啶、表阿霉素、环磷酰胺）及他莫昔芬或卵巢去势；无一包含紫杉烷类、赫赛汀、雷洛昔芬及芳香化酶抑制剂。

Our experiments confirmed that two known inhibitors DRB and A3 Inhibited the activity of purified recombinant human CK2 holoenzyme, and that quercetin, its derivatives and some tyrphostins exerted stronger inhibitory effect on CK2 than DRB and A3. These results provided important experimental basis and a simple screening method for the development of more effective inhibitors of CK2 and their clinical application in the future.

本结果实验证实纯化的重组人CK2全酶可受到已知抑制剂DRB和A3的抑制，但槲皮素及其衍生物和某些Tyrphostins抑制CK2的作用较DRB和A3更强，这对于开发更有效的CK2抑制剂，为今后应用于临床提供了重要的实验依据和一种较为简便的筛选方法。

METHODS The inhibitory effect of nobiletin on proliferation of SMMC-7721 cells was assessed by MTT analysis and growth curve assay. Morphological changes under microscope were observed by Giemsa staining. Hepatic cancer H22 model in mice was performed through subcutaneous inoculation of Right-Sidedness Axilla of KM mice. Different dosages of nobiletin 125, 250, 500mgkg^(-1 were injected by intragastric gavage everyday.

不同浓度的川陈皮素作用于人肝癌细胞SMMC-7721细胞，用MTT法、细胞生长曲线实验研究其对SMMC-7721细胞的生长抑制作用，Giemsa染色观察细胞形态变化，初步研究其体外抑瘤作用；建立小鼠H22肝癌移植性实体瘤模型，研究川陈皮素对肝癌的体内抑制作用。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！