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Objective: To explore the effects of heroin dependence on the expression of somatostatin, interleukin-2 (IL-2) positive cells in gastric antrum of rats.

目的:探讨海洛因依赖对大鼠胃窦生长抑素、白细胞介素2(IL-2)阳性细胞表达的影响。

Plasma motilin, somatostatin and cholecystokinin were determined by radioimmunoassay.

运用放射免疫同批测定血浆胃动素、胆囊收缩素和生长抑素水平。

Purpose: To study the clinical significance and somatostatin in patients with colon cancer.

目的 :研究胃泌素和生长抑素含量的变化及其对大肠癌的临床意义。

Recombinant hANG had no effect on the expression of VEGF and bFGF in both SMCC-7221 cells and HUVEC cells, suggested that hANG exerted its antiangiogenic role not through the inhibition of the autosecretion and parasecretion of angiogenic stimulatory factors VEGF and bFGF.

重组人血管抑素对SMMC-7721肝癌细胞及HUVEC细胞中两种血管生长刺激因子VEGF和bFGF的表达没有影响,提示血管抑素对肿瘤血管生长的抑制作用不是通过抑制血管生长刺激因子的自分泌和旁分泌来实现的。

Recombinant endostatin is a specific inhibitor of chick chorioallantoic membrane angiogenesis and human vitelline vein endothelial cell ECV-304 proliferation. The recombinant endostatin regressed established syngeneic B16 melanoma tumor in mice.

重组内皮抑素能够抑制鸡胚尿囊膜血管生成和人脐静脉内皮细胞ECV-304的增殖,在小鼠体内实验中对黑色素瘤产生良好的抑瘤效果(P<0.01)。

DISCUSSION: In obese individuals, somatostatin analog significantly reduced postprandial sensations after a satiating meal without altering maximum tolerated meal volume or postnutrient gastric volume, suggesting an effect on upper gut sensation.

讨论:对于肥胖的个体,生长抑素类似物明显减少饱食后进餐后的感觉,但并没有改变最大进餐耐受容积或营养后的胃容积,提示生长抑素类似物影响上消化道的感觉。

Most 5-HT cells appeared in the base part of gland in the rat, while in the human they were mainly located in the intercellular substance and a few scatted in the glandular epithelium.

方法采用免疫细胞化学方法,检测人和大鼠胃窦部粘膜内生长抑素细胞、胃泌素细胞、5-羟色胺细胞(5-HT细胞)、嗜铬粒素A细胞的分布。

The above results suggest that the inhibitory effect of centrally administrated HA on gastric acid secretion is mediated by vagi, acetylcholine M receptor and somatostatin.

结果提示:HA的中枢抑酸效应由迷走神经传出,可能通过乙酰胆碱M受体及引起生长抑素释放实现。

Firstly, without the participation of L-Cys, urokinase can also hydrolyse plasminogen to generate angiostatin.

第一,我们的实验结果表明尿激酶酶切纤溶酶原获得血管抑素这一反应过程无需FSD参与,至少可以确认FSD不是血管抑素生成的必备条件。

But it in 10"8mol/L-10"mol/L inhibited gastrin secretion .whereas it promoted somatostatin secretion of duodenum in vitro. GnRH-A did not effect significantly gastrin and somatostatin secretion of stomach in vitro.These results suggested that GnRH-A may integrate with GnRH receptor and restrain directely gastric acid secretion in parietal cell.

综上所述,我们认为胃腔内的Gn尺H类似物可能首先和壁细胞上GnRE受体结合,直接抑制壁细胞胃酸的分泌,由于胃酸分泌减少反馈性地刺激胃泌素细胞,促进其合成及分泌胃泌素,胃酸分泌减少同时也反馈性的抑制生长抑素的释放,反馈性地抑制胃肠壁内EC细胞分泌5一HT。

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