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Our results showed that the total dendrite branch length and arborization of hippocampal neuron were not affected by the inhibition of ASICs for a short time, while the total dendrite branch length was reduced and dendrite development was impaired if ASICs were inhibited for a long time.It suggested that ASICs play a role in the dendrite development,which may help understand how ASICs affect the formation of neuronal networks and participate in higher brain fuctions such as learning and memory.

结果发现短时间抑制ASICs的功能并不影响海马神经元的树突总长度和分支,而长时间抑制ASICs的功能则会降低树突总长度,影响树突的发育,表明ASICs参与调节树突的发育,这将有助于理解酸敏感离子通道如何影响神经网络的形成,并进而参与学习记忆等高级脑功能。

Baxter, working on cats under experimental conditions comparable to ours, however, reported that intravenous injection of adrenalin either had no marked effect or a slightly augmentative effect on the histamine-induced secretion, and that stimulation of the splanchnic nerve yielded similar results.

若用较长的间隔如每10—30分钟收集一次胃分泌,则此双相效应就会被掩盖,因而得出肾上腺素对猫胃分泌无明显效应或有增加分泌的效应的结论,如Baxter等人所得到的一样。在急性实验中,刺激大内脏神经对组织胺引起的猫胃分泌有显著的抑制效应。与肾上腺素的效应不同,刺激大内脏神经的效应通常是单相的。

Thus , nitric oxide inhibits cytochrome oxidase activity in neurones and glia , resulting in down-regulation of mitochondrial energy production .

在神经元和神经胶质细胞中,一氧化氮抑制细胞色素C氧化酶的活性,抑制线粒体能量产生。

A new antibody releasing system has been developed by covalently attachingIgG to the biodegradable hyaluronic acid hydrogel via the hydrolyticallyunstable hydrazone linkage, aiming to deliver the antibody of CNS regenerationinhibitors to the injured brain. Furthermore, pH sensitive linkage-hydrozone has beenformed between hydrogel and antibody.

这一将该材料植入成年缺损大鼠的大脑皮层后,该材料具有良好的神经相容性,能够抑制胶质瘢痕的形成,并能诱导神经胶质细胞的迁移进入材料,为轴突的再生提供良好的生物为环境,促进神经轴突长入将改性后的水凝胶。

For example, removal of the GABAergic inhibition on raphe nuclei results in au excitation of serotonergic neurons which play a key role in endogenous analgesia system.

实际上,吗啡或内源性释放的ME和β-EP激活上述神经回路,可能是通过"脱抑制",即对抑制性的GABA能经元的抑制而实现的。

Radiolabeled pharmacological binding assay showed: 1 BmK AS bound specifically to a single class of non-interacting binding sites on both rat brain and cockroach nerve cord synaptosomes with high affinity and low low capacity. The association of BmK AS with both synaptosomes was quick to reach equilibrium, but the dissociation seemed to be only partial. The specific binding of BmK AS was independent of membrane potential, and couldn't be modified by veratridine. Moreover, the binding of BmK AS could be inhibited by native BmK AS, BmK AS1, BmK IT2 and BmK IT on both synaptosomes, but not or partially inhibited by BmK Ⅰ and suggesting BmK AS type neurotoxins might bind to a distinct receptor site on mammal and insect sodium channels with a similar manner from β-scorpion toxins.

二。蝎毒素多肽配体与哺乳动物和昆虫靶离子通道受体的药理结合特性及其靶结合位点的研究:经放射性标记结合和竞争抑制实验表明:1)BmK AS在大鼠脑和蟑螂神经索突触体上有单一非协同性高亲和力低结合容量结合位点,能快速结合并达到平衡,但仅能部分解离,其结合不依赖于膜电位,也不受藜芦碱调节,天然的BmK AS,BmK AS-1,BmK IT2和BmK IT可抑制〓AS与两种突触体的特异结合,而BmK Ⅰ无或仅有部分抑制效应。

Third, it has a discussion on the development of modern and traditional artificial neural network technology and their application in image processing. It summaries that the model of the Pulse-coupled neural network based on Elkhorn's model of the cat visual cortex was constructed according to the mammalian vision systems. The nonlinear modulation property, which is a generic and pervasive biological pulse-coupling mechanism, is used in the construction of PCNN. So, PCNN finds many applications in image processing, including segmentation, edge extraction et al. As all known, the performance of the image segmentation depends not only directly on the adjustment of PCNN parameters and the statistical properties of image but also on the cyclic iteration times N of PCNN. If the parameters have been properly set, it turns out to be essential to select a suitable criterion to determine N.

回顾了神经网络技术的现状,指出传统人工神经网络只利用了生物神经元有限的属性进行模型构建,而90年代产生的脉冲耦合神经网络充分利用了哺乳动物视神经网络特有属性,其神经元模型除了考虑生物神经元特有的线性相加、兴奋与抑制属性外,还考虑到生物神经元特有的非线性相乘调制耦合特性;考虑了哺乳动物视神经系统视野受到适当刺激时,相邻连接神经元同步激发产生35Hz~70Hz振荡脉冲串特性等,所以PCNN网络模型更靠近真实生物视觉特性,特别是哺乳动物视神经网络,特别适合计算机图像处理应用,尤其在生物细胞图像分割、图像平滑、降噪及图像中目标的分类、计数等方面的研究。

H reflex recovery curve examimation shows that electric acupuncture can obviously suppress neuron excitability of motor neuron pool in cornu anterius medullae spinalis, decrease accentuatal tension of muscle and Liddell and Sherrington reflex.Conclusions: electric acupuncture can relieve spasm of limbs after cerebral apoplexy.

实验结果说明:针刺阳陵泉缓解脑卒中后肢体偏瘫痉挛状态,可能与针刺刺激提高了中枢神经系统中抑制性氨基酸递质受体的表达,使受体数量增加、敏感性提高,从而提高了抑制性神经递质的效率,使下位中枢运动神经元兴奋性受到抑制有关。

Further, a hemagglutination elution test revealed that the 6593S virus was unable to release from hemagglutinated RBC. Through the protein structure modeling, it was suggested that the change in amino acid residue 443 of neuraminidase might alter the neuraminidase catalytic sites.

而进一步透过蛋白质结构模拟分析,可以知道6593S小溶斑病毒神经胺酸酶第443个胺基酸残基的改变,使得小溶斑病毒神经胺酸酶酵素催化位置和唾液酸及神经胺酸酶抑制药物之间结合的键结有所改变,此结果可和实验结果相互印证。

Which can be used as the body of vitamin B1 coenzyme of many enzymes in the normal human body has an important role in glucose metabolism, it can inhibit the activity of cholinesterase, and choline esterase is an important neurotransmitter, and thus nerve conduction impact; vitamin B2 in the organization by participating in a variety of yellow enzymes constitute a coenzyme, its role in bio-oxidation process in the delivery of hydrogen role in regulating the body's metabolism process; vitamin B6 can also be a variety of enzymes as coenzyme participate in all kinds of amino acid metabolism, promote the absorption of amino acids and protein synthesis, cell growth is necessary for the material, which also promote fat metabolism, involved in neurotransmitter synthesis, hemoglobin synthesis and the impact on the normal reproductive functions such as human body an important metabolic process, Volkswagen Medicine Net: What liver protection effect of vitamin B family?

可作为维生素乙许多酶的辅酶,在正常人体组织中有一个用糖代谢的重要作用,能抑制胆碱酯酶活性,和胆碱脂酶是一个重要的神经递质,神经传导,从而影响;由黄色参与各种酶在组织中维生素B2构成辅酶,其作用在生物氧化氢的作用,调节人体的代谢过程中产程;维生素B6也可以是作为辅酶参与氨基酸代谢的各种酶的品种,促进氨基酸的吸收和蛋白质合成,细胞生长是必要的材料,这也促进脂肪代谢的神经递质合成,血红蛋白合成和参与,如影响人体生殖功能的正常新陈代谢过程中一个重要的,(大众医药网:什么样的维生素B家庭肝脏的保护作用?

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

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双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。