抑制真菌的

The invention relates to the isolation and preparation of an active fraction from plant Cuminum cyminum, its further purification and standardization as chemically defined entity with their intended use as drug bioavailability enhancer for the drugs belonging to therapeutic categories such as antimicrobial, antifungal, anti-viral, antitubercular, antileprosy, anti-inflammatory, antiarthritic, cardiovascular, antihistaminics, respiratory distress relieving drugs, immunosuppressants, anti-ulcerogenic, anti-cancer, CNS drugs, corticosteroids, nutraceuticals in compositions to be administered orally/parenterally, topically, inhalations, rectally, vaginally in human beings and/or veterinary conditions.

本发明涉及植物孜然芹中的一种活性级分的分离和制备，进一步的纯化以及它作为化学确定实体的标准化，和它作为治疗类药物的生物利用率增强剂的特定用途，这类药物包括如抗微生物剂、抗真菌剂、抗病毒剂、抗结核药、抗麻风病药、抗炎药、抗关节炎药、心血管类药、抗组胺药、呼吸窘迫缓解药、免疫抑制剂、抗溃疡药、抗癌药、CNS药、皮质甾类药、营养制品，它们以组合物的形式通过口服/肠胃外，局部，吸入直肠，阴道施用于人和/或兽医学病症中。

Chinese Cinnamaldehyde Cinnamaldehyde alias, Lauraceae plants are dry skin and cinnamon bark obtained by steam distillation of volatile oil in the main component of research in recent years are more root canal sterilization drug, it can seriously undermine the bacterial cell surface structure, and thus has a wider antibacterial spectrum and strong antibacterial activity; gallnut hundred, also known as worms, insect species are Schlechtendalia Schlechtendalia or times aphid eggs in their parasitic plants Anacardiaceae Rhus chinensis, Green bran Yang Yang, such as bran or red tree gall formation, the main ingredient for gallnut tannin, can solidification microbial protoplasts and a variety of body enzymes, a wide range of bacteria, fungi, yeasts are inhibited.

中药桂皮醛别名肉桂醛，是樟科植物肉桂的干皮及树皮经水蒸气蒸馏得到的挥发油中的主要成分，是近年来研究较多的根管消毒药物，它能够严重破坏细菌细胞表面结构，从而具有较广的抗菌谱和较强的抗菌活性；五倍子又名百虫，是倍蚜种昆虫角倍蚜或倍蛋蚜在其寄生漆树科植物盐肤木、青麸杨或红麸杨等树上形成的虫瘿，其主要成分为五倍子鞣质，能够凝固微生物体内的原生质及多种酶，对多种细菌、真菌、酵母菌都有明显的抑制作用。

Chinese Cinnamaldehyde which also named Cinnamaldehyde alias, is the main component of volatile oil which obtained by steam distillation from dry skin and cinnamon bark of lauraceae plants . It is researched as a root canal sterilization drug in recent years, it can seriously undermine the bacterial cell surface structure, and thus has a wider antibacterial spectrum and strong antibacterial activity; gallnut hundred, also known as worms, it is a kind of gall that be formatted by Schlechtendalia species of insects including Schlechtendalia and times aphid eggs in their parasitic plants Anacardiaceae Rhus chinensis, Green bran Yang or red bran Yang, the main ingredient for gallnut tannin, can solidification microbial protoplasts and a variety of body enzymes, a wide range of bacteria, fungi, yeasts are inhibited.

中药桂皮醛别名肉桂醛，是樟科植物肉桂的干皮及树皮经水蒸气蒸馏得到的挥发油中的主要成分，是近年来研究较多的根管消毒药物，它能够严重破坏细菌细胞表面结构，从而具有较广的抗菌谱和较强的抗菌活性；五倍子又名百虫，是倍蚜种昆虫角倍蚜或倍蛋蚜在其寄生漆树科植物盐肤木、青麸杨或红麸杨等树上形成的虫瘿，其主要成分为五倍子鞣质，能够凝固微生物体内的原生质及多种酶，对多种细菌、真菌、酵母菌都有明显的抑制作用。

Magainin is the skin secretion product of Batrachia under the eriviroment pressure, which can be used to accelerate the fusion rate of wound and resist the infection. It can inhibit the growth of bacteria and fungus with the lowest concentration; Protegrin is isolated from porcine leukocyte hi 1993 and is useful as antiviral agents.

Magainins是爪蟾的皮肤在一定的环境压力下分泌出的抗感染和促进伤口愈合的成分，低浓度便可抑制许多细菌和真菌生长；Protegrin是1993年从猪的中性白细胞中分离得到，研究发现它具有抗爱滋病毒的功能。

It was found that zymosterol in S. cerevisiae GL7 cells and cycloartenol in P. wickerhamii cells were accumulated when treated with solasodine. Zymosterol and cycloartenol are respective substrates of sterol 24Cmethyltransferase in S. cerevisiae GL7 and P. wickerhamii, hence we deduced that sterol C-24-methyltransferase is the main target of solasodine.

根据澳洲茄胺对S.cerevisiae GL7和P.wickerhamii的甾醇生物合成途径的抑制结果均积累24位甾醇甲基化转移酶的底物，分别是zymosterol和cycloartenol，初步阐明了澳洲茄胺的主要作用靶点是24位甾醇甲基化转移酶，而其它几种抗真菌生药活性成分不影响甾醇的生物合成途径。

More and more evidence supports that RNAi,co-suppression in plants, and quelling in fungi shares the same basic molecular mechanism. It indicates that this mechanism was acquired during early evolution.

目前的研究表明，RNA干涉与植物中的共抑制、真菌中的基因压制很可能具有共同的基本分子机制。

The antimicrobial activity of thyme oil to different mould and bacteria, the lowest antimicrobial concentration, and the preservation effect of fresh cut wax gourd treated with different concentrations of rhyme oil/chitosan compound preservation liquid at room temperature were investigated.

通过GC-MS对百里香精油的化学成分进行了鉴定，研究了百里香精油对不同真菌和细菌的抑制效果及最低抑菌浓度，考查不同浓度百里香精油／壳聚糖复合保鲜液在室温条件下对鲜切冬瓜的保鲜效果。

San-Huang, so called Mesima in Japan and Korea, has been considered to be a traditional Chinese and Japanese medicine that was reported to be used as a stypti, both internally and externally, for treating uterine bleeding, and for blood in the urine. The modern researches proved that it is also an effective emmenogogue for amenorrhea and for treating leukorrhea. Extracts from hot water have been experimented to have antitumor and inhibit Sacroma 180 cancer cell abilities. The powdered fruiting body is taken in liquid or in pill form, and preparations can also be applied externally for pains in the abdominal region.

在传统的药用真菌中，桑黄在明代李时珍的「本草纲目」即有记载，性寒，味微苦，能利五脏，宣肠气，排毒气，压丹石，人热发，止血等，在中国及日本有长久的使用历史，现代化科学研究证实桑黄的热水抽出物具有抑制老鼠Sacroma 180肿瘤细胞及一般抗肿瘤的功能，治妇女月经不顺，提高免疫机能及强化T细胞能力，对癌症肿瘤切除后化疗的患者具有相乘的功效且长期服用并不会有任何副作用及毒性产生，这些证据显示「桑黄」确实具有开发潜力。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失