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New substituted benzimidazole compounds, compositions, and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided.

提供了式的新型被取代的苯并咪唑化合物、组合物和抑制与人或动物个体体内肿瘤生成有关的激酶活性的方法。

Glycerin and the glycol matter behind the combustion, not only may make smoker trouble bladder cancer, moreover the what comes into being acrolein may restrain the air tube and cilium secreta from lung inner snapout, increase the chance suffering from the tracheitis and emphysema thereby , make the person state of illness developing this two kinds disease increase weight and.

甘油和乙二醇在燃烧后的物质,不但可能使吸烟者患膀胱癌,而且所产生的丙烯醛可抑制气管和纤毛分泌物从肺内排出,从而增加患气管炎和肺气肿的机会,并使患有这两种病的人病情加重。

Approximately 30% of many populations carry the heightened arousal mutations, while around 60% carry the depressant mutation.

大约30%的人群携带者性欲增高的基因变异,约60%的人携带性欲抑制的基因变异。

In this study, we found out that linalool, a small-molecule compound, could inhibit the growth of various human lymphocyte leukemia cell lines significantly. Meanwhile, it showed little toxicity to normal hematopoietic cells. To determine effects of linalool on the growth of a serious of human leukemia cell lines and normal hematopoietic cells and to explore its possible mechanisms, we employed various technologies, including MTT assay, Flow cytometry, Human Cancer PathwayFinder II Gene Array, Western Blot, RT-PCR and so on.

我们在筛选抗肿瘤小分子化合物时,发现天然小分子化合物芳樟醇能明显抑制多种人淋巴细胞白血病细胞增殖,而对正常人骨髓造血细胞及外周血细胞的增殖没有明显的影响,为此我们用MTT技术、流式细胞术、肿瘤相关信号通路分析技术以及Western blot、RT-PCR等手段和方法探讨了芳樟醇对不同类型白血病细胞系及相应正常造血细胞中的影响情况,及其诱导白血病细胞凋亡的可能分子机制。

Advocates of tiger farming, such as economist Barun Mitra, of New Delhi's Liberty Institute, have argued for years that plentiful stocks of tiger parts for sale in a free market would thwart poachers and crossborder profiteering.

支持老虎养殖的人,如新德里自由研究所的经济学家巴朗。米塔等,近年来一直认为,自由市场中有充足的老虎器官供买卖能够起到抑制偷猎者及跨境倒卖牟取暴利的作用。

Moreover, exogenously added IL-4 inhibited SsAg-induced decrease of Bcl-2, caspase-3 activation, and apoptosis in CD4+ T cells from healthy subjects.

此外,外加介白质-4可以抑制健康人的CD4阳性T细胞之金黄色葡萄球菌超级抗原引起的Bcl-2的减少、caspase-3的活化、及细胞凋亡。

Objective To explore the effects of low-dose mifepristone on human granulosa cells and the molecular mechanism of its inhibiting or delaying ovulation.

目的 观察低剂量米非司酮对体外培养的人卵巢颗粒细胞的影响,探讨其抑制或延迟排卵的分子机制。

The expression of survivin mRNA was assessed by RT-PCR; Cell cycle analysis; the cell cycle distribution of semiconfluent cell cultures was determined by follow cytomytric analysis of the content of propidium iodide-stained DNA.

本研究的目的就是通过bFGF刺激培养的人肝癌细胞株Bel-7402,并通过PI3K抑制剂wo咖annin阻断PKB的信号转导通路,以观察凋亡抑制蛋白Survivin mRNA的变化。

Results The rate of FLS proliferation was significantly reduced in groups treated by sinomenine.

结果 经青藤碱干预后的人成纤维样滑膜细胞的增殖率受到显著抑制(P.05),其中高剂量组的改变差异尤为显著(P.01)。

Trichinella showed a certain inhibiting effect on the growth of HCT-8 cells in BALB/c mice.

旋毛虫对BALB/c小鼠体内的人结肠癌HCT-8细胞的生长有一定的抑制作用。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。