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Qinghao acid, Qinghao B, Scopoletin, Casticin and Chrysosplenol D had some antimalarial activities on P. berghei. Even when the dosage was up to 500 mg/kg/d, the maximal inhibition rate was only 59%, which is less active than QHS. Therapeutic effect of different ingredients of A.

青蒿酸、青蒿乙素、东莨菪内酯、青蒿黄酮1、青蒿黄酮2 5种成份对鼠疟均有不同程度的抑制作用,但剂量高达500mg/kg/d时,抑制率最高也仅达到59%,远低于QHS的疗效。

When HIV-1 in culture medium was exposed to a range of concentrations of urokinase, a dose-dependent inhibition of infectivity was observed in a variety of lymphoma and leukemia cell lines including MT4, CEM, H9, and peripheral blood mononuclear cells using assays for reverse transcriptase, P24 antigen and syncytia formation.

通过检测逆转录酶活力,P24抗原的表达和合胞体形成情况发现尿激酶可以抑制人体免疫缺损病毒对多种淋巴瘤和白血病细胞系,如MT4、CEM、H9和外周血单核细胞的侵染能力,并且这种抑制与尿激酶浓度呈剂量依赖关系。

The experimental results showed that Taurocholic Acid can reduce the capillary permeability in inflammation tissue, can restrain the inflamed swelling and inhibit the generation of inflammatory mediators, such as NO, PGE2 and histamine.

结果:牛磺胆酸能够降低炎症组织毛细血管的通透性,抑制炎症性肿胀,抑制NO、PGE2、组胺等炎症介质的产生。

PTX at tenuates the ALI induced by LPS or sepsis in rat. The therapeutic effects of PTX include:improve oxygenation, at tenuate pulmonary edema formation, enhance animal survival in sepsis-induced ALI. The mechanisms may related with the effects of PTX inhibiting the chemotaxis, migration, activation of inflammatory leukocytes, diminishing the production of active oxygen, and inhibiting inflammatory cytokine release partly.

4PTX对大鼠内毒素性ALI及脓毒症性ALI均有一定的防治作用,主要表现在改善动脉血氧合,减轻肺水肿形成,提高脓毒症性ALI大鼠的存活率等方面,其机理可能与抑制白细胞趋化与激活,减少肺内白细胞渗出及活性氧产生,一定程度上抑制炎性细胞因子生成等有关。

The change of GR plays an impor trant role in low suppressive effect of PLA2.There was a negative correlation between PLA2 and GR from early stage to 72 hours after injury. The suppressive effect of glucocorticoid to PLA2 is relative to GR.

2GR减少是PLA2抑制作用低下的重要因素,早期至72hPLA2与GR改变呈负相关,糖皮质激素对PLA2 的抑制作用与GR水平密切相关。

No considerable effect was observed on the COX activity of P.falciparum treated with daphnetin-Fe complex. The tyrosyl free radical was tested to reflect the RNR activity of P.falciparum at various times by ESR.

结果 体外同步培养的恶性疟原虫经瑞香素(100 μmol/L)作用2、4、8和12 h后,COX活性分别被抑制了0、6%、73%和80%;在瑞香素浓度为0.1、1、100和1 000 μmol/L,作用6 h后,COX活性分别被抑制3%、31%、53%和84%;而瑞香素-Fe复合物对COX的影响几乎消失。

Results The compositions of 28 Chinese herbs can inhibit the growth of 5 bacteria in different levels, but the effects on other 3 bacteria are not obvious. Quercetin and usnic acid have better effects on 5 bacteria than other 26 herbs compositions, with MIC 0.03125~0.125mg/ml and 0.0156~0.0625mg/ml.

结果 28种中药有效成分对3种牙周细菌抑制作用不明显,对另5种口腔常见细菌有一定的抑制作用,其中松萝酸和槲皮素有较强的抑菌作用,MIC值分别在0.0156~0.0625mg/ml和0.3125~0.125mg/ml之间。

(1) Oxidative/antioxidative reactions, inflammatory reactions, apoptosis in lung are involved in the pathogenesis of HILI;(2) ABX, rHuEPO have protective effects on HILI respectively;(3) Hyperoxia can increase VILI in rats, but has little effects with low tidal volume mechanical ventilation.

结论(1)氧化抗氧化失衡,炎症反应,肺内细胞凋亡参与了高氧所致成年大鼠肺损伤的过程;(2)ABX通过抗炎、抗氧化、抑制细胞凋亡作用对成年大鼠高氧肺损伤具有保护作用;rHuEPO通过抗炎、抗氧化、抑制细胞凋亡及一定程度的抗纤维化作用对成年大鼠高氧肺损伤具有保护作用;(3)高浓度氧能明显加重大鼠通气机所致肺损伤,而高浓度氧对小潮气量通气影响较小。

The suppressing effect of BJ fly ash on ASR expansion of siliceous gravel, zeolitic perlite and silica glass in 1M NaOH solution were studied at 40℃, 60℃ and 80℃ respectively. It is indicted that the suppressing effect of one certain fly ash on ASR expansion various with temperature and the reactivity of aggregate.

通过BJ粉煤灰在40℃、60℃、80℃的1M NaOH溶液中对硅质砾石、沸石化珍珠岩和石英玻璃ASR膨胀抑制效果的研究,发现同种粉煤灰在不同温度下对ASR膨胀抑制效果随温度和集料种类而异。

Further, we found that phenytoin couldn't inhibit the LPS-induced IkappaB-alpha degradation suggesting that this drug might not affect LPS-induced activation of NF-kappaB by abrogating the LPS-induced IkappaB-alpha?ndegradation.

在机转方面,我们证实phenytoin并不能有效抑制经LPS活化所造成ΙκB-α的降解,因此,我们推论phenytoin的抑制作用可能不是经由NF-kappaB这条路径。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。