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Some new sulfonamide derivatives possessing potent CA inhibitory properties act as effective in vitro tumor cell growth and metastasis inhibitors.

一些新型的磺胺类碳酸酐酶抑制剂可有效抑制体外多种肿瘤细胞系的生长和转移。

Ethanol inhibition was not affected by 5 nM and 20 nM calyculin A (a phosphatase 1/2A inhibitor). Prior superfusion of 5 nM and 20 nM KT5720 also attenuated ethanol inhibition of NMDA-mediated depolarization. 1 μM and 3 μM chelerythrine, a selective protein kinase C inhibitor or 20 nM calyculin A did not affect ethanol inhibition of NMDA-induced response.

当以表面灌流方式,事先给予5 nM或20 nM KT5720时,同样可以减少乙醇抑制NMDA引发的去极化作用;分别给予1 μM或3 μM chelerythrine或20 nM calyculin A则不会影响乙醇抑制NMDA所引发的反应。

Further studies showed that HIV entry inhibitors could inhibit the syncytium formation in a dose-dependent manner.

进一步发现特异性的HIV进入抑制剂能够抑制合胞体的形成,且具有剂量依赖性。

TGIF may overcome the invasion and metastasis of GS by inhibiting the expressions of MMP9 and VEGF.

TGIF能通过抑制VEGF和MMP9的表达抑制胃癌的转移。

After transfection with TGIF ASDON, the proliferation of SGC-7901 cells was partially inhibited, and its inhibition rate was increased to 20.4% at 72h, whereas it has no effect on cell cycle and apoptosis in SGC-7901 cells.

SGC-7901细胞转染TGIF反义寡核苷酸后,细胞增殖受到部分抑制,72h后,它的抑制率为20.4%,但细胞的凋亡和细胞周期分布无明显改变。

The inhibition of Lactobacillus fermentation filtrate was investigated by MTT-method, and the fatty acid, thallus nucleic acid on Hela cell were studied in different time.

用MTT法研究不同浓度乳酸杆菌DM9811发酵滤液在不同时间对Hela细胞的抑制作用,在此基础上研究脂肪酸、菌体核酸在不同时间对Hela细胞的抑制作用。

Methods:Microcalorimetry was used to determine the bacterial growth thermogenesis curves under different conditions.

利用微量量热法,测定了大肠杆菌在不同条件下的生长热谱曲线,得到了相应的生物热动力学参数,如生长速率常数、抑制率、半抑制率(IC50 )、热焓。

Three learning and memory-related genes, SNAP-25, Tob and hippyragranin, were obtained and subjected to further study.

第三脑室注射反义核酸抑制SNAP-25的表达,损害步下抑制性回避任务的长时记忆,而不影响其短时记忆。

The growth speed of the cells with transfected Tob gene got slowly, even to a growth arrest.

结论Tob基因转染后的胶质瘤细胞生长受到明显抑制,出现向正常胶质细胞的分化和凋亡现象,提示Tob基因确实是一胶质瘤细胞增殖抑制基因,值得进一步做功能研究和实验性基因治疗研究。

Flow cytometry analysis revealed that NIT transiently transfected cells were arrested in G2 phase.

在HeLa细胞中大量表现NIT蛋白可以抑制细胞的生长,同时也可以抑制细胞生成聚落的能力。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。