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It's has been reported that lactoquinomycin and frenolicin B, analogues of kalamycin, can inhibit AKT for the pyran naphthoquinone skeleton they have. We found that although kalamycin has pyran naphthoquinone skeleton, but did not suppress AKT and its downstream signal system, then we make a sytematic analysis on the in vitro anti-tumor effect and mechanism of kalamycin.

有报道其类似物lactoquinomycin和frenolicin B是肿瘤靶点AKT抑制剂,并由此推断吡喃萘醌骨架在AKT抑制过程中发挥主要作用,我们发现虽然卡拉霉素含有吡喃萘醌骨架,但是并不抑制AKT及其下游信号系统;继而对卡拉霉素的体外抗肿瘤作用及其机理进行了系统的分析。

The protective mechanism of ischemic preconditioning combined with pyrrolidine dithiocarbamata may be due to reduce the apoptosis of human lung cells and the release of inflammatory cytokines by inhibiting the expression of NF-Кb protein .

2缺血预处理联合PDTC对肺的保护机制可能是抑制了NF-Кb蛋白表达活性从而使肺实质细胞凋亡下降及抑制炎症介质的释放。

Similarly, the Ca~(2+)-regulated K~+ channel blockers, BaCl_2 and quinidine decreased the K~+ current and slowed migration of B-16 melanoma cells.

结果表明,ET-1可以抑制这种细胞的钾电流,同时还可以抑制细胞的迁移。

AIM: To study the effects of paecilomyces cicadidae total polysaccharides on the immune function and free radical scavenging of tissue, in immunosuppressed rats.

目的:观察蝉拟青霉总多糖对免疫抑制大鼠组织器官免疫功能调节和自由基代谢的影响,探讨其对免疫抑制大鼠组织器官的免疫调节和抗衰老作用。

AIM: To study the effects of paecilomyces cicadidae total polysaccharides on the immune function and free radical scavenging of tissues in immunosuppressed rats.

目的:观察蝉拟青霉总多糖对免疫抑制大鼠组织器官免疫功能调节和自由基代谢的影响,探讨其对免疫抑制大鼠组织器官的免疫调节和抗衰老作用。

And Cucumis sativus L. were tested by bioassay-guided separation. The extracts from P. tomentosa flower with ethanol were extracted with petroleum ether, ethyl acetate and n-butanol. The inhibition rate of the ethyl acetate extract to growth of the 3 kinds of plant radicel were 99.89%, 63.53% and 32.74% respectively at 0.5 mg/mL concentration, and that of petroleum ether were 76.30%, 56.17% and 23.36%.

绒叶泡桐Paulownia tomentosa花乙醇提取物依次用石油醚、乙酸乙酯、正丁醇和水萃取后进行活性测定,结果表明,石油醚萃取物在浓度为0.5mg/mL时,对反枝苋、生菜和黄瓜种子胚根生长的抑制率分别为76.30%、56.17%和23.36%;乙酸乙酯萃取物在浓度为0.5mg/mL时,对反枝苋、生菜和黄瓜种子胚根生长的抑制率分别为99.89%、63.53%和32.74%。

The suitable inhibitive concentration was 0.5%. In Chinese-style sausage, Weeping forsythia can reduce the rate of lipid oxidation and rancidity during the periods of storage.

将连翘添加于中式香肠中,可有效抑制中式香肠贮存过程中的脂肪酸败,其抑制作用随连翘在中式香肠中浓度的提高而加强。

Methods Samples of 12 patients with RAU active phase were studied by it suppressor assay.

应用刀豆碱(concanavalin A, ConA)激活产生的淋巴细胞抑制检测法探查了12例溃疡期患者外周血淋巴细胞的抑制活性。

RECK is a tumor suppressor gene, the expression in benign and malignant breast tissues is a negative relationship.

RECK作为一种抑癌基因,在乳腺良恶性肿瘤中表达呈负相关,可抑制MMP-9的表达,从而抑制乳腺癌的发生和转移。

An illustration of the concept of burning surface regression is given in Figure 1, for a section of a hollow cylindrical grain, with an inhibited outer surface ("inhibited" means that the propellant surface is protected from the heat of combustion and as such, burning does not occur).

一个例子的概念,燃烧表面的回归,是由于在图1 ,对于第一个空心圆柱粮食,与一抑制外表面("抑制"是指推进剂表面是保护从燃烧热和作为,例如,燃烧不会发生)。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。