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The Hyal-2/WOX1 complex is internalized and translocates to the nuclei, and this complex appears to exert growth suppression in normal epithelial cells.

命名为WWOX、FOR 或 WOX1)这个肿瘤抑制性蛋白质移动过来与 Hyal-2 结合,接下来 Hyal-2/WOX1 complex 深入细胞内部,继而移行进入细胞核,进一步导致正常上皮细胞的生长抑制作用。

Biological activities of SPThe inhibitory effect of SP on oxidation of lipids and the acitivity of lipoxygenase, the scavenging or quenching effect of SP on free radicals, and the influences of SP on the malonaldehyde content in mice liver juice, liver mitochondria and liver red blood cell were studied. The results showed that SP can inhibit the auto-oxidation of lard and soybean oil at 60 and can inhibit the activity of lipoxygenase significantly; SP also had scavenging effect on hydroxylradicals generated by Fenton system with IC50 value 6.220 mg/ml, under the concentration range of 1 mg/ml-50mg/ml, the scavenging rate of SP to -OH increased strongly when the concentration of SP increased, the maximum scavenging rate was 85.4%.

大豆多肽的生物活性研究研究了大豆多肽抗油脂氧化、抑制脂肪氧合酶及清除自由基的作用,以及对小鼠肝组织匀浆、肝线粒体和红细胞丙二醛含量的影响,结果显示:在60℃时,大豆多肽对猪油与豆油的自动氧化均有一定的抑制作用:对脂肪氧合酶的抑制作用显著:对Fenton体系产生的羟基自由基具有明显的清除作用,其IC_(50)值为6.220mg/ml。

Antioxidative activity of flavonoids from Lespedeza bicolor were investigated by examining the scavenging effects on hydroxyl radicals and superoxide anion O2(superscript - and the inhibitions on auto-oxidation of lard, rape seed oil, and linoleic acid, The results showed that LBF had significant scavenging functions to free radical and superoxide anion, and the scavenging effect increased with the increase of the content of LBF; LEF can remarkably inhibit auto-oxidation of lard, rape seed oil, and linoleic acid, indicating its potential as a natural antioxidant.

通过二色胡枝子黄酮(Lespedeza bicolor flavonoids, LBF)清除羟自由基、超氧阴离子的效果及抑制猪油、菜油、和亚油酸的自氧化来研究二色胡枝子黄酮的抗氧化活性。其研究结果表明,二色胡枝子黄酮对清除自由基有显著性作用,且清除率随黄酮浓度的增加而增大;能够极显著地抑制猪油、菜油、亚油酸的自氧化(P.01),抑制作用随浓度的增大而增强。作为天然的抗氧化剂,二色胡枝子黄酮具有一定的开发利用价值。

Methods Human breast cancer cell line SKBr3 cells were treated with celecoxib for 24 h and 48 h at 4 different concentrations, respectively.

目的 探讨环氧合酶-2(COX-2)抑制剂塞来昔布对人乳腺癌细胞SKBr3的抑制增殖及诱导凋亡作用。

The results showed that the sandy soil in layered soil profile can stimulate or obstacle the water movement as compared to the uniform loam column with 50cm depth of water table, this was mainly determined by the position of the sand layer.

结果表明,砂层对于水分的蒸发既有促进也有抑制作用,在地下水埋深为50 cm时,5 cm厚的底砂层可使水分的蒸发强度增加10%~20%;砂层距水位的距离大于5 cm时,砂层可抑制水分的蒸发,且当距离增加到35 cm左右,其抑制率可达70%~80%;当砂层距水位的距离继续增大时,水分的蒸发强度基本保持不变。

Inhabition of NX0 and NX1 on the activities of fumaric reductase in tissue homogenate of cysticerci was tested. The results showed that the two kinds of benzimidazol carbamate drugs could inhabite the activity of fumaric reductase complex noncompetently.

测试了NX0和NX1对猪囊尾蚴组织匀浆延胡索酸还原酶活性的抑制作用,结果表明两种苯并咪唑氨基甲酸酯类药物非竞争性抑制延胡索酸还原酶复合体活性。

The results showed that the three disparate treated substances have no visible antibacterial effect to E. coli , but a obvious effect to Staphylococcus aureus with inhibition of about 10 bacteriostasis units; have dissimilar effects to 10 kinds of fungi among the total kinds, and have a good inhibitory effect to Cytospora.coccodesHughes with fungistasis rate above 65%. After the gel filtration and activity detection, 50mM ammonium acetate was screened out as the more suitable eluents, the crudes were separated into strikingly unlike parts with obviously different antimicrobial activity.

结果表明,大蜡螟抗菌物质对大肠杆菌没有明显的抑制作用,而对金黄葡萄球菌抑制作用明显,抑菌活性单位在10左右;对10种植物病原真菌均有不同的抑菌活性,其中对苹果树皮腐烂病菌的抑制率达到65%以上;经过凝胶过滤分离,及对分离组分的抑菌活性测定,筛选出较合适的洗脱液为50mM乙酸铵,各分离组分抑菌活性差异明显,粗提物被分成了两个差异显著的部分。

RESULTS The results indicated that PCF could significantly increase the viability of thymocytes and enhance the activities of SOD, GSH-Px, CAT in cells. PCF decreased the amounts of ROS and the rate of apoptosis in cells. PCF inhibited the morpholog alteration of the thymocytes irradiated by UVB and maintained the ultrastructure of cells in normal. PCF attenuated UVB caused DNA fragmentation in thymocytes. While combined ERKs inhibitor yielded typical DNA fragmentation, co-treatment of thymocytes with PCF and JNKs and p38 kinase inhibitors completely blocked UVB-induced DNA fragmentation.

结果 PCF能显著提高UVB辐射后小鼠胸腺淋巴细胞的活性;提高胞浆中SOD、GSH-px、CAT的活性,降低ROS含量及细胞凋亡率;抑制UVB辐射所致的胸腺淋巴细胞凋亡的形态学改变,维持细胞的正常超微结构;抑制UVB所致的胸腺淋巴细胞DNA片段的出现;预先应用ERK抑制剂使DNA片段增加,给予JNK和P38抑制剂后协同PCF使DNA片段带减少。

The results of inhibitor addition to methanogens and to eubacteria showed that both groups of anaerobes especially methanogens played important role in the process of dechlorination.

加入甲烷菌抑制剂氯仿、真细菌抑制剂青霉素降低了PCP脱氯速率,表明甲烷菌对还原脱氯有重要影响,其它厌氧微生物也有不同程度的影响。

YSR was obtained from other foliages, and its function effect was obvious.

从其他植物源中筛选出对小麦籽粒发芽抑制效果显著、作用迅速而持久的天然抑制物质YSR。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。