抑制的

We analyzed mRNA quantily with RT-PCR method, and think that the repressor element 5 maybe represses the expression in translation level.

在此基础上，用RT-PCR方法对mRNA进行定量分析，初步确认这个抑制元件对蛋白表达的抑制过程是在翻译水平上。

Objective:To explore the role and mechanism of suppression of ribonuclease RNase inhibitor in the growth of glioma cells.

摘 要：目的：探讨核糖核酸酶抑制因子对脑胶质瘤生长的抑制作用及可能机理。

BMI-1(B-cell-specific Moloney murine leukemia virus integration site 1), a Polycomb group repressor, is always present as a PcG complex combined with RING1, HPC2, Mph2, et al. BMI-1 prolongs cells'capacity to proliferate and represses their senescence by repressing the transcription of CDKN2A through acetylhydrolasing or deacetylhydrolasing the Polycomb response elements in chromosome.

BMI-1 (B-cell-specific Moloney murine leukemia virus integration site 1)属于PcG家族，它与该家族其他成员如RING1，HPC2，Mph2等结合形成蛋白复合体，作用于染色质PREs位点，通过对组蛋白进行乙酰化和去乙酰化修饰，从而稳定抑制CDKN2A转录，最终促进细胞的增殖并抑制细胞凋亡。

ResultsPe Min Kam Wan, Lam Kam Sang Nasalin and Wo Chun Tong clearly inhibited PCA in mice and reduced histamine release from rat mast cells induced by compound 48/80. But,Sinuwell did not affect the PCA. In addition, the ethanol extracts from Senecio scandens, Selaginella tamariscina and Xanthium sibiricum significantly inhibited PCA in mice, but the extracts from Angelica dahurica, Magnolia liliflora and Cassia tora failed to affect it.

结果速效鼻敏感丸、林金生鼻敏清胶囊及和春堂鼻敏清片明显抑制小鼠异种被动皮肤过敏反应，减少compound 48/80诱导的组胺释放，而速效鼻敏素胶囊对被动皮肤过敏反应无明显影响；速效鼻敏感丸及和春堂鼻敏清片主要组成药物九里明、卷柏和苍耳子显著抑制小鼠异种被动皮肤过敏反应，而白芷、辛夷和决明子无明显作用。

Results In the pyramidal neurons voltage-clamped at -60 mV, GABA evoked a transmembrane inward current and the peak amplitude of the current increased sigmoidally with increasing doses of GABA applied. Co-application of lidocaine resulted in a decline of IGABA and the IGABA was 4.05mmol/L.10mmol/L lidocaine resulted in right shift of concentration-response curve arid not only EC50 changing from 7.72mmol/L to 17.2mmol/L but also the maximal current unable to reach the top level.

结果 将钳制电位固定在－60mV，GABA以剂量依赖性方式诱导出内向电流；利多卡因明显抑制GABA诱导的Cl电流I(下标 GABA，50%抑制浓度(IC50)为4.05mmol/L，10mm/L可使GABA浓度效应曲线明显右移，50%有效浓度(EQ50)由7.72mmol/L增加到17.2mmol/L，且最大电流明显降低。

Citric acid is a good selective depressant in the floatation separation of sillimanite from quartz because it strongly depresses the metal ions activation of quartz and slightly depresses...

柠檬酸对金属离子活化石英有很强抑制作用，而对硅线石抑制作用较弱，是浮选分离硅线石和石英较好的选择性抑制剂。

Results ①Arsenicals caused inhibition obviously on HL-60 cells growth at the test concentrations,particularly in the groups of 2μmol/L,10μmol/L sodium arsenite,and the groups of 100 μmol/L,300 μmol/L sodium arsenate.

结果①两种无机砷化物对HL-60细胞生长具有抑制作用，特别是高浓度NaAsO2（2、10 μmol/L）和Na3AsO4（100、300 μmol/L）可明显地抑制HL-60细胞的生长

Researchs suggested that ceramide and sphingosine could inhibit mitosis and DNA synthesis of cancer cells, promote apop

细胞水平研究发现神经酰胺和鞘氨醇能抑制结肠癌细胞有丝分裂和DNA合成，促进细胞凋亡，影响Fas、Bcl-2、Bcl-10、bax和P53等凋亡相关蛋白的表达，即神经酰胺和鞘氨醇能通过抑制结肠癌细胞生长、促进细胞凋亡发挥抑癌作用。

Furthermore, in the CTA rats, compared with water stimulability, FLI neurons of SON and DMV induced by sucrose stimulability had had much more expressions.6 When the same sucrose stimulability was given, FLI neurons expressions of SON, DMV and LH in the CTA rats were much lowwer than that in the control rats.Conclusions:1 CTA had an inhibitory effect on small intestine peristalsis, indicate taste preference has an effect on small intestine peristalsis, and inhibitory effect induced by CTA is corresponded with US, this effect may have relations with vagus efferent never and humoral regulation.2 In the electrophysiology experiment, discharges of vagus efferent never in the CTA rats are much more than that in the control rats, indicates taste and taste preference may regulate small intestine peristalsis via vagus nerve, and dicharge can continude 1 hour, indicate humoral regulation also exists in the regulation.

结论1建立味觉厌恶对小肠运动有抑制作用，提示味觉嗜好性对小肠运动有影响，而且味觉厌恶引起抑制作用是与条件刺激成对应关系的，味觉刺激引起的小肠蠕动的抑制作用可能与迷走神经传出神经及体液调节有关。2在电生理实验中，CTA大鼠迷走神经传出放电高于对照组的大鼠，提示味觉及味觉嗜好性可能是通过迷走神经对小肠运动进行调节的，放电至能持续60min，表明味觉及味觉对小肠运动的调节中还有体液调节的参与。

Result］ The extracted liquid from D. stramonium could decrease the germination rates of 4 vegetables and the seed germination of tomato and pepper. After treatment by 0.2, 0.4 g/ml extracted liquid , the seed germination of tomato and pepper were decreased by 10.2％, 9.4％ and 46.7％, 34.7％ than that of CK resp. The extracted liquid at 0.2 g/ml could inhibit the growth of vegetable root, but had some promotion on growth of vegetable stem. The extracted liquid at 0.4 g/ml had the strong inhibition on the growth of vegetable root, but its inhibition on growth of vegetable stem was greatly variable in different species.

结果］曼陀罗浸提液可降低4种蔬菜种子的发芽速率，降低番茄和辣椒种子的发芽率；0.2、0.4 g/ml曼陀罗浸提液处理后，番茄和辣椒种子的发芽率分别比对照降低了10.2％、9.4％和46.7％、34.7％。0.2 g/ml曼陀罗浸提液抑制蔬菜根的生长，而对茎的生长却表现出促进作用；0.4 g/ml曼陀罗浸提液对蔬菜根的生长有很强的抑制作用，对茎段生长的抑制作用因物种不同而有很大差异。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。