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Methods The stablishment of lymphoblast cell lines was by EBV-immortalization and subtyping of the cell lines by cell fusion, mytomycin C inhibition analysis and/or immunoprecipitation and Westemn blot.

方法将我国3例FA患者外周血细胞用EB病毒活化法建立原始B-淋巴细胞系,采用丝裂霉素生长抑制试验和细胞融合后MMC抑制试验的互补试验进行分型;利用单克隆抗体免疫沉淀法和Western blot法进行分型。

Production of methyl mercaptan declines with inhibiting the enzyme activity.

抑制METase活性即可抑制甲基硫醇的生成。

Interestingly at l2h Cinnamylaldehyde could increase HUVEC adherence to THP-1.(5) At 4h and l2h Muscone decreased PMN-HUVEC adhesion, as well as inhibited ICAM-1, VCAM-1 and CD44 expression on TNF-primed HUVEC. But it markedly increased HUVEC adherence to THP-1 at 12h.

结果提示:黄芪多糖、川芎嗪、桂皮醛和麝香酮可以抑制PMN与HUVEC粘附并抑制HUVEC表面粘附分子的表达,桂皮醛和麝香酮能明显促进THP-1与HUVEC粘附。

In preclinical studies, oral active DPP-IV inhibitors also promoted beta-cell proliferation, neogenesis, and inhibition of apoptosis in rodents.

临床前研究显示,啮齿类动物经口给予二肽肽激酶IV抑制剂(如sitagliptin与vildagliptin)也引起促进β细胞增生与胰岛新生,抑制β细胞碉亡的作用。

In preclinical studies, oral active DPP-IV inhibitors also promoted -cell proliferation, neogenesis, and inhibition of apoptosis in rodents.

临床前研究显示,啮齿类动物经口给予二肽肽激酶IV抑制剂(如sitagliptin与 vildagliptin)也引起促进β细胞增生与胰岛新生,抑制β细胞碉亡的作用。

At pre-operation, post-operation 6 h, 3 d and 7 d detect the leave of plasm prethrombotic state molecular marker tissue factor, tissue factor pass inhibitory, thrombus precursor protein, plasminogen activator inhibitory-1(PAI-1), P-Selectin, Thrombin-Antithrombin complexes, D-dimer with ELISA, transmission immunity nephelometer. Results Malignant tumor patients, the levels of plasma TF, TpP, D-D in 6 h and 3 d of post-operation rose to peak value.

分别于术前、术后6 h3、d和7 d用ELISA、透射免疫比浊法检测其血浆血栓前状态分子标志物D-二聚体(D-dimer, D-D)、血栓前体蛋白(thrombus precursor protein, TpP)、凝血酶抗凝血酶复合物(thrombin-antithrombin complexes, TAT)、组织因子(tissue factor, TF)、P选择素(P-Selectin, P-S)、组织因子途径抑制物(tissue factor pass inhibitory, TFPI)、纤溶酶原激活物抑制物1(plasminogen activator inhibitory-1, PAI-1)的水平。

GD can notedly decrease the expression of NF-κB and NF-κB mRNA in the abdominal aorta of AS rabbits damaged with sacculus proprius, and then may prevent the occurance of RS, which may he a part of the mechanism of preventive effect of GD.

冠心通络方减轻血管内膜增生、防止血管再狭窄的内在机制可能在于抑制NF-κB活性,进而抑制血管平滑肌细胞增殖、血管内膜增生。

Results In the aspect of oocyst intensity discharged from mice, femal BABL/C mice were more than the male, the 50 day-old mice(26 g~28 g) were more than the 25 and 75 day-old, mice in 15 mg/L group were more than those in the and mice infected after immunosuppressed for 3 days were more than those infected after immunosuppressed for –6,-3,0,6,9 days.

结果 雌性小鼠排卵囊强度均较同日龄雄性小鼠大,而不同日龄小鼠中又以50日龄(26 g~28g)小鼠排卵囊量最多;各剂量组小鼠中,15 mg/L组排卵囊强度较其他各组大,10 mg/L组小鼠次之;免疫抑制时间各组中,免疫抑制3天后感染的小鼠排卵囊强度较其他组大。

Results: Absorbance shows good linear relationship to the cell number in the range of 0.25×10^5-2×10^5 cell mL^(-1). The concentration limit for the testing samples without cytotoxicity was 7.812mgmL^(-1). The testing samples significantly inhibited the oversecretion of TNF-α and IL-8 in HL-60 cells stimulated by LPS.

结果:细胞密度在0.25~2×10^5 cellmL^(-1)范围时,吸光度与细胞数呈良好的线性关系;供试液无毒界限为7.8l2mgmL^(-1);三种给药方式均能显著抑制LPS诱导HL-60细胞释放TNF-α和IL-8,其中供试液与LPS共育时抑制作用最强。

The group disposed by Acetylspiramycin doesn"t show parallel results; The strip gray scale of exotoxin A decreased gradually with the increasing dosages of Azithromycin and Roxithromycin, which doesn"t show in group disposed by Acetylspiramycin and group PAO-JP2; The strip gray scale of lasR, detected by RT-PCR, decreased gradually with the increasing dosages of Azithromycin, which doesnt show in group PAO-JP2.Conclusions: There were obvious differences between PAO1 and PAO-JP2 in biology characteristics in vitro.

本研究发现大环内酯类药物在生物被膜培养过程中分别处理PAO1、PAO-JP2,结果提示大环内酯类药物(14、15元环)通过对QS系统的影响可有效抑制铜绿假单胞菌生物被膜的形成;通过QS系统有效抑制铜绿假单胞菌的毒力因子的产生,16元环的大环内酯类药物乙酰螺旋霉未见上述结论;lasR基因的反转录结果提示阿奇霉素可在转录水平抑制QS系统发挥其作用。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。