抑制的

Results:The results show that the survival rate of mammary epithelial cells were decreasing gradually with the increasing of the time of TGF-β1 treatment, and the survival rates of 24 h and 48 h groups were significantly lower than that of control group (p.05); the LDH activity of 6 h、12 h、24 h and 48 h groups were significantly higher than that of control group (p.05); the DNA degradation arisesed in 12 h, 24 h, and 48 h groups' mammary epithelial cells; the activity of Caspase-3 reach to a peak at 24 h, which was significantly higher than that of control group (p.05); the acinus of epithelial cells appears to break off and collapse with the increasing of treatment time, but the leydig structure keeps integrate;...

结果表明：1、5、10 ng/mL的TGF-β1均能抑制乳腺上皮细胞的增殖，且随浓度增加抑制作用加大，呈现剂量依赖性，其中10 ng/mL TGF-β1组与对照组差异显著（P.05）；10 ng/mL TGF-β1作用于乳腺上皮细胞24 h，随作用时间延长细胞凋亡率逐渐增加，6 h、12 h和24 h组与对照组相比差异极显著（P.01）；LDH活力也不断升高，6 h、12 h和24 h组与对照组差异显著（P.05）；DNA随 TGF-β1作用时间的延长发生不同程度降解；TGF-β1作用2 h~6 h细胞大量表达HSP70，6 h达到高峰，而后下降，2~12 h的表达量均显著高于对照组（P.05）。结论：TGF-β1可以抑制奶牛乳腺上皮细胞的增殖，具有浓度依赖性。10 ng/mLTGF-β1。。。

The bioactive screening on aldose reductase, nitric oxide synthetase, liver cancer Bel-7402, cavum oris epithelioma KB and colon cancer HCT-8 showed that paeoniflorin inhibited the nitric oxide synthetase by the rate of 83. 4% at the concentration of 5μg/ml, and paeoniflorigenone inhibited the colon cancer HCT-8 cells by the rate of 83. 2% at the concentration of 5μg/ml.

通过醛糖还原酶、NO合酶、肝癌Bel-7402、口腔上皮癌KB以及结肠癌HCT-8五种模型的生物活性筛选表明，在51μg／ml的浓度下，芍药甙对NO合酶的抑制率达83.4％，芍药甙元对结肠癌HCT-8细胞株的抑制率达83.2％，有较好的抑制作用。

131I-AS inhibits proliferation of endothelial cells in vitro and inhibits LLC growth in vivo and it outdoes AS or 131I alone.

131I-AS在体外能明显抑制内皮细胞的生长，在体内能明显抑制小鼠Lewis肺癌移植瘤的生长，其抑制作用强于单纯的等浓度的AS和131I。

These results suggest that morphine withdrawal selectively impairs the cued fear extinction through inhibiting the ERK phosphorylation in the amygdale and mPFC. Histamine deficiency not only enhances acquisition the cued and contextual fear conditioning and but also potentiates the impairment of extinction of cued fear memory.

这些结果提示：吗啡戒断能选择性抑制恐惧记忆的消除，此作用是通过抑制杏仁核和mPFC脑区内ERK蛋白磷酸化来实现的；组胺缺乏能增强线索和背景恐惧记忆的获得以及增强吗啡戒断对线索恐惧记忆消除的抑制作用。

The electric capacity coupling matching and inductance coupling match are two kinds of forms that conducted coupling, passing the analysis to constitute the mechanism and principle to them, putting forward repressing a few of their methods: Match the length that can adopt to let up to lead line and enlarge the line to be apart from to the electric capacity coupling ,.

电容性耦合和电感耦合是传导耦合的两种形式，通过对它们构成机理以及原理的分析，提出了抑制它们的几种方法，如对于电容性耦合可以采用减小导线的长度、增大线间距，平衡法，对干扰源和被干扰源进行屏蔽等方式进行抑制干扰；对于电感耦合可以用减小互感，局部形成耦合环，对干扰源进行屏蔽等方式来对干扰进行抑制。

Cinnamomea, antrocamphin A was purified from previous ethanol extraction using bioactivity-guided fractionation. As results, the antrocamphin A could significantly inhibit NO and PGE2 autacoids production in LPS-induced RAW 264.7 macrophage cells. Meanwhile, the mRNA and protein expression levels of iNOS and COX-2 were inhibited by antrocamphin A in a dose-dependent manner. Antrocamphin A also reduced the translocation of NF-κB induced by LPS, which was associated with the prevention of the degradation of I-κB, and subsequently decreased p65/p50 proteins level in the nucleus. This is the first report demostrating the A.

接著并以活性为导向的分离策略，从樟芝子实体乙醇抽出物中分离出具抗发炎活性成分antrocamphin A，续利用LPS诱导小鼠巨噬细胞（RAW 264.7）产生发炎的模式，解析antrocamphin A之抗发炎机制，结果证实antrocamphin A确可有效抑制一氧化氮自由基和前列腺素的生成，透过蛋白质表现分析得知，antrocamphin A之抗发炎活性是经由抑制一氧化氮生成酵素和第二型环氧酵素的mRNA表现，进而抑制了一氧化氮生成酵素、第二型环氧酵素和核转录因子-κB等酵素之表现。

5-LOX participate in the formation of retinal neovascularization,Selective inhibition of 5-LOX can reduce the expression of VEGF and its receptor KDR, its specific mechanism may be associated with inhibition of ERKs signaling.

5-LOX参与视网膜新生血管的形成，通过对其选择性抑制可下调VEGF及受体KDR的表达从而抑制新生血管的生成，具体机制可能与抑制5-LOX激活MAPKs信号通路的外部ERKs有关。

Result A strain of Pseudomonas cepacia was detected in 1.6% compound quaternary ammonium disinfectant before application. The amount of the germ was 1.21×105cfu/ml. The strain had the similar resistance to chlorine-containing disinfectants and glutaraldehyde compared with Staphy aureus. The contaminated disinfectant could still thoroughly destroy the antigenicity of HBsAg with 60min's contact after diluted for 5-20 times.

结果 该洋葱假单胞菌对氯和戊二醛的抗力与大肠杆菌和金黄色葡萄球菌接近，污染样液除菌后1 000倍稀释对大肠杆菌和金黄色葡萄球菌仍有较好的杀菌效果，20倍稀释可完全破坏HBsAg抗原性，和抑制枯草杆菌黑色变种芽胞的生长，1 600倍稀释可抑制白色念珠菌生长，而原液则不能抑制分离菌株的生长。

But it in 10"8mol/L-10"mol/L inhibited gastrin secretion .whereas it promoted somatostatin secretion of duodenum in vitro. GnRH-A did not effect significantly gastrin and somatostatin secretion of stomach in vitro.These results suggested that GnRH-A may integrate with GnRH receptor and restrain directely gastric acid secretion in parietal cell.

综上所述，我们认为胃腔内的Gn尺H类似物可能首先和壁细胞上GnRE受体结合，直接抑制壁细胞胃酸的分泌，由于胃酸分泌减少反馈性地刺激胃泌素细胞，促进其合成及分泌胃泌素，胃酸分泌减少同时也反馈性的抑制生长抑素的释放，反馈性地抑制胃肠壁内EC细胞分泌5一HT。

The trypsin inhibitor activity of sporamin was determined using the method of Smith, and show a fairly linear relationship with the concentration of sporamin between an region of the inhibitor rate from 20% to 70%. The R^2 was 0.983 and the trypsin inbitor activity was (735.32±12.11) TIU/mg.

采用Smith推荐的方法测定了sporamin的胰蛋白酶抑制剂活性，拟合分析结果表明：在对胰蛋白酶抑制率为20%~70%的范围内，胰蛋白酶抑制率与sporamin的浓度呈线性关系，回归系数R^2为0.983。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。