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Keratin antibody IgM 3B4 to the adhesion of Candida albicans to malpighian cells, human buccal epithelial cells and endothelial cells of fetal umbilical vein. RESULTS: It was found that the different concentrations of natural monoclonal anti??keratin antibody IgM 3B4 could inhibit Candida albicans germ tube formation and adhesion of Candida albicans to malpighian cells, human buccal epithelial cells and endothelial cells of fetal umbilical vein.Its inhibitory action was positively related to the level of natural monoclonal anti??

结果:与对照组比较,不同浓度的单克隆天然抗角蛋白抗体IgM 3B4均能抑制白念珠菌芽管生成,并且抗体浓度越高,抑制白念珠菌芽管形成的作用越明显;同时单克隆天然抗角蛋白抗体IgM 3B4能够显著减少白念珠菌与角质形成细胞、上皮细胞、内皮细胞的粘附,其抑制作用与单克隆天然抗角蛋白抗体IgM 3B4的浓度呈正相关。

Results: Proliferation of K562 cells was significantly inhibited by naringenin and the IC50 at 24, 48 and 72h were 455, 225 and 175μmol/L respectively. Cell growth inhibition and apoptosis were observed under light microscope and transmission electron microscope. Observation by flow cytometry indicated that K562 cells were blocked in G0/G1 phase of cell cycle in naringenin group, and S phase cells were remarkably decreased. PCNA expression in each treatment group was remarkably less than in control group.

结果:柚皮素对K562细胞增殖有明显抑制作用,作用24,48和72h后的半数抑制浓度(IC50)分别为455,225和175μmol/I;柚皮素处理组细胞在普通光镜和电镜下均见观察到显著的增殖抑制和典型的细胞凋亡形态学改变;流式细胞仪分析证实柚皮素能使K562细胞聚积在G0/Gl期,S期细胞减少;在处理组PCNA的表达显著低于对照组。

These changes were prevented by genistein (a protein tyrosine kinase inhibitor) and antioxidant N-acetyl-L-cysteine, but promoted by sodium orthovanadate (a protein phosphatase inhibitor), which were administered to the SD rats 20 min before ischemia.

进一步的研究表明,缺血前20 min腹腔注射给药,然后缺血30 min,发现蛋白酪氨酸激酶抑制剂染料木黄酮和抗氧化剂N-乙酰半胱氨酸能显著地抑制核内STAT3的磷酸化水平及DNA结合活性的增加(磷酸化水平从2.3和2.5倍分别降为1.2和1.4倍, DNA结合活性则从2.8和3.7倍分别降为1.1和1.5倍),而蛋白酪氨酸磷酸酶抑制剂矾酸钠则能明显地促进他们的增高(磷酸化水平从2.0倍增到3.4倍, DNA结合活性从3.1倍增为5.1倍)。

Application of EBR induced parthenocarpic growth accompanied with active cell division in Jinchun No.4, a cultivar without parthenocarpic capacity, whereas Brz treatment inhibited fruit set and subsequently fruit growth in Jinchun No.2, a cultivar with natural parthenocarpic capacity, and this inhibitory effect could be rescued by application of EBR.

在非单性结实的津春4号黄瓜栽培品种的子房上添加EBR可以诱导单性结实并且提高细胞分裂能力,而在单性结实的津春2号黄瓜栽培品种的子房上喷施BRs合成抑制剂抑制果实生长,最终导致败育,而这种抑制现象可以通过添加EBR得以恢复。

Methods Spectrophotometry was used to study the activity of PLAP in the presence and absence of L Leu. PLAP relative activity was calculated according to the absorbance variation.

方法应用分光光度法分别测定有L-Leu和无L-Leu存在下的酶活力,根据其活力变化求出酶的相对活力;用双倒数作图法,确定L-Leu对PLAP的抑制类型并求出其抑制常数;同时也观察了pH对抑制作用的影响。

And 37. 1%, respectively. The results suggest that 18α-GA down-regulated CYP expression at the transcriptive levels.

表明GL在转录水平下调大鼠肝细胞CYP1A1,CYP2E1和3A1表达,以对CYP2E1的抑制作用最强,对CYP3A的抑制作用最弱,对CYP1A1的抑制作用居中,与整体动物的酶学实验结果基本一致。

But both 20 years and 2 years old of pu-erh tea extracts show a strong inhibitory effects against 2-AAF. In addition, tannic acid, gallic acid, rutin, umbelliferone, and quercetin exhibited stronger antimutagenicities against PhIP than apigenin; while all of these polyphenols displayed inhibitory effect against 2-AAF.

而比较数种多酚类化合物发现,tannic acid、gallic acid、rutin、umbelliferone和quercetin对於抑制PhIP的抗突变作用比apigenin来的有效,但是apigenin和其他多酚类化合物对於抑制2-AAF的抗突变作用则均具有明显的抑制效果。

Previous studies show that p33ING1b is involved in growth inhibition, apoptosis, chromatin remodeling, DNA repair, tumor suppression and cellular senescence, but its biochemical function and involvement in cellular senescence is still not fully uncharacterized.

p33ING1b是一个较晚发现的肿瘤抑制基因 ING1的主要表达形式,自从被成功克隆以后得到了广泛的研究,已有的研究表明,p33ING1b参与了细胞的生长抑制、凋亡、染色质重塑、DNA损伤修复、肿瘤抑制和细胞衰老等。

The results showed that the different molecular weight of the complexes of Chitosan with copperor zinc, the complexes of carboxymethyl Chitosan with copper and the low-molecular-weight iii complexes of sulfation chitosan with copper had excellent inhibition on Valsa mali. The low-molecular-weight complexes of chitosan with copper had inhibition on Botyosphaeria berengeriana. All of samples had no inhibition on Fusarinm oxysporium.f.sp.vasinfectum and Alternaria Solani under this test conditions.

结果 发现,不同分子量的壳聚糖 Cu、Zn配合物、羧甲基壳聚糖 Cu配合物及低分子量的壳聚糖硫酸酯 Cu配合物对苹果腐烂病菌有明显的抑制作用;低分子量壳聚糖 Cu配合物对苹果轮纹病菌有一定的抑制效果;所有配合物在试验浓度范围内,对棉花枯萎病菌和蕃茄早疫病菌均无抑制作用。

The mycelial growth of Rhizoctonia solani was promoted by vanillic acid and syringic acid at levels of 0.1~1 mM/L, and it was inhibited remarkably by p-counaric acid of over 1mM/L and modestly by ferulic acid. The radial extent of mycelia of Fusarium solani was increased significantly by ferulic acid of 0.1~1 mM/L and limitedly by p-coumaric acid. vanillic acid had paradoxcial effects on the growth, positively at low levels and negtively at high levels, on which Syringic acid had a slight effect.

试验结果显示:浓度为0.1~1mM/L的丁香酸对西洋参立枯丝核菌菌丝生长具有促进作用,香草酸也有一定的促进作用,但不呈浓度效应,浓度在1mM/L以上的香豆酸对其有显著的抑制作用,阿魏酸也有一定抑制作用;对于西洋参根腐菌,阿魏酸对其生长有明显促进作用,香豆酸也有一定促进作用,香草酸表现为低浓度促进,高浓度抑制作用,0.1~1mM/L丁香酸对其生长基本无影响。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。