抑制地

The algorithm of new strain wave that will put forward through example and Lee filter wave, broad sense is various Xiang Jiaquan all is worth configuration filter wave and with all possible means the effect that Xiang Jiaquan all is worth configuration filter wave to undertake inhibition spot of be concerned with makes clear as a result quite, this algorithm restrains the noise in image effectively not only, and the geometrical structure feature that better land maintains image.

通过实例将提出的新滤波算法和Lee滤波、广义多方向加权均值形态滤波和多方向加权均值形态滤波进行抑制相干斑的效果比较结果表明，该算法不仅可以有效地抑制图像中的噪声，而且较好地保持图像的几何结构特征。

The extracellular edelfosine promoted the phosphatization of Spmlvia inducing the expression of Mid2; The intracellular edelfosine increased the phosphatization of Spmlvia inhibiting the expression of Pmp1, and leading the holdback of cytokinesis.

细胞外依地福新诱导Mid2蛋白的表达，从而促进的Spm1磷酸化；细胞内依地福新通过抑制Pmp1蛋白的表达，取消Pmp1蛋白对Spm1的抑制作用，使Spm1的磷酸化程度增加，最终导致粟酒裂殖酵母细胞胞质分裂障碍。

Simulation results also show that saddle-shaped distributed AMF can more effectively inhibit constriction of vacuum arc.

对于小电流扩散态真空电弧，重点仿真分析不同电弧电流与不同纵向磁场对其关键特性的影响，部分仿真结果进行了实验验证；对离子处于超音速流动的收缩态真空电弧的仿真表明，真空电弧的磁收缩主要是由于霍尔效应引起的，离子温度和电子温度沿轴向先增大后减小，马鞍形分布的纵向磁场能够更有效地抑制真空电弧的收缩，而且阴极斑点分布对真空电弧特性也有着显著的影响；对离子处于亚音速流动状态的大电流真空电弧的仿真表明，部分等离子体不能到达阳极而损失，马鞍形分布的纵向磁场能够更有效地抑制电弧等离子体的损失，同时能使阳极电流密度和能流密度的分布更加均匀。

However, dexamethasooe did not seem to affect the sustained current and the sustained component of the biphasic current induced by ATP. The in hibitory effect of dexamethasonc on ATP induced currents was blocked by glucocorticoid receptor antagonist RU38486 (10μmol/L) and protein kinase A inhibitor H-89 (10μmol/L), but not by G protein inhibitor GDP-β-S (0.2mmol/L) and protein kinase C inhibitor chelerythrine chloride (10μmol/L).

地塞米松对ATP激活电流的快速抑制作用可被糖皮质激素受体拮抗剂RU38486(10μmol/L)、蛋白激酶A抑制剂H-89(10μmol/L)阻断，而G蛋白激活抑制剂GDP-β-S(0.2mmol/L)、蛋白激酶C抑制剂Chelerythrine chloride(10μmol/L)对地塞米松的快速抑制作用无明显影响。

Firstly, the paper, combining the characteristic of synchronous pulse bursts and inhibition with the modified PCNN model, presents a way of finding the foveation points in the images adaptively and effectively, and simulates the human vision system. Secondly, PCNN is extended to PCNNs, based on the properties of information couple and transmission, an algorithm that is used to fuse images of the same target got by several sensors to an image is presented to simulate the human vision system. Thirdly, combining the properties of synchronous pulse bursts, capture, and transmission and competition of waves, the paper presents two ways of classification, one is an algorithm based on the properties of neuron to capture and inhibit to classify the data taking on any complex unlinear distribution robustly, the other is based on the restricted distance and modified of the former to remove the influence of inferior samples in classification; Finally, based on the accumulative difference pictures, and the forming and transmission of PCNN wave, selecting and controlling the direction of autowave by connecting the neighbouring neurons selectively, the paper presents a way to simulate the tracks of moving object and detect the moving direction.

首先结合PCNN的同步脉冲发放和侧抑制特性，提出了基于改进型PCNN的图像凹点检测算法，该算法是一种自适应而有效的图像凹点检测方法，并且较好地仿真了人类视觉系统；然后，结合信息传递和信息耦合特性，将PCNN扩展成PCNNs，提出了一种基于PCNNs的图像融合算法，能够将多个传感器获取的同一目标的图像信息融合到一幅图像中，有效模拟了人类视觉系统；另外，结合PCNN的同步脉冲发放特性、捕获特性和波的传播竞争特性，开拓地将PCNN用于模式分类中，提出了基于耦合神经元点火捕获／抑制特性的分类方法和改进的约束距离下的PCNN分类方法，前者可实现对样本空间中任意复杂分布训练样本的稳健非线性分类，而后者能够消除训练样本中刺点对分类的影响；最后，结合累积差分图像思想、PCNN波的形成与传播特性，通过各神经元之间连接取向来选择与控制自动波的流向，将PCNN用于运动视觉分析中的运动轨迹模拟及运动方向检测。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

Fifty percent of depressed patients exhibit nonsuppression of cortisol secretion after administration of the dexamethasone suppression test.

一项为地塞米松抑制试验，研究发现50%的抑郁症患者给予地塞米松后其皮质醇分泌并未被抑制。

Mg/ kg way partially inhibited by L- NAME,or by sodium orthovanadate(50 ug/ kg),a potent inhibitor of protein tyrosine phosphatase;(2)genistein also decreased the PP of renal vascular bed in a dose-dependent manner and the effect of genistein was completely inhibiteby pretreatment with sodium orthovanadate,but unaffected by L- NAME;and(3 genistein decreased the PP of mesenteric vascula bed in a dose-dependent manner,an effect which was partially inhibited by sodium orthovanadate,but unaffected by L- NAME .

mg/ kg引起的效应；(2)向肾血管灌注环路中直接注射GST也可剂量依赖性地降低肾动脉的灌流压，预先注射正钒酸钠可完全抑制GST引起的效应，而L- NAME对此效应没有影响；(3)肠系膜血管灌流环路中注射GST可剂量依赖性地降低其灌流压，这一效应可被正钒酸钠部分抑制，而L- NAME对此无影响。

When the concentration of chitosan was 0.05 mg/ml in PDA culture medium, the colony growth of Botrytiscinera Persoon Fries and physalospora piricora nose was restrained remarkably; when the concentration of chitosan was 0.5 mg/ml, the colony growth of Sphaerotheca humuli. Burrill was restrained observably.

在含毒介质法的PDA培养基中，当壳聚糖浓度为0.05mg/mL时，草莓白粉病菌和梨轮纹病菌的菌落生长极显著地抑制（p＜0.01）；当壳聚糖浓度为0.50mg/mL时，草莓灰霉病菌的菌落生长极显著地抑制（p＜0.01）。

Firstly, the parallel growth inhibition experiment of S. pombe wild-type cells, spm1△, pmp1△, mid2△and relevant retransform strains were carried out in order to farther confirmed the effect of edelfosine on spm1, pmp1 and mid2 genes.

因此，本实验的目的是探讨依地福新对经Mid2介导的，Pmp1抑制的MAPK Spm1信号通路的影响，以阐明依地福新抑制粟酒裂殖酵母细胞胞质分裂的作用机制。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。