抑制地

The inhibition type and inhibition constant of L Leu on PLAP were determined by using the double reciprocal plot.

结果L－Leu对PLAP有明显地抑制作用，抑制程度与pH有关；双倒数作图得到一组平行线，Ki为1.98mmol／L。

We carried out the experiment that edelfosine acted on the nucleus division and detected the DNA content of S. pombe, and analyzed the effect of edelfosine on nucleus division of S.

(1)、应用粟酒裂殖酵母细胞和Jurkat细胞的生长抑制试验，确定依地福新抑制粟酒裂殖酵母细胞生长的作用剂量。

Previous studies have found the major metabolic way of clivorine in male rat liver microsomes was to form pyrrolic metabolites. The above results suggested that there is sexual difference of metabolism in rats. The major in vitro metabolic way of clivorine in guinea pig was hydrolysis.

FMO的特异性抑制剂methimazo1e可以显著地抑制〓的形成，但对〓的形成无明显的抑制作用，且〓在肝微粒体中的形成为NADPH非依赖性，上述结果提示参与〓和〓代谢的酶分别为肝微粒体中的水解酶和黄素单氧化。

The SPECT imaging of ~(99)Tc~m-GEBP11 can show the tumor mass clearly and ~(131)I-GEBP11 has anti-tumor effect with weak toxicant and secondary effect, which is the foundation for them to develop nuclide probe or radiotherapeutics drugs targeting to tumor vasculature.3. GEBP11 can inhibit angiogenesis, which comes true probably through its inhibition effects on the proliferation, invasion, migration and adherence of ECs.

1、GEBP11具有活体内胃癌血管靶向结合的能力，它与胃癌血管内皮细胞膜受体特异结合后可被内化。2、~(99)Tc~m-GEBP11 SPECT成像能较好地显示体内肿瘤灶，~(131)I-GEBP11具有明显的抗肿瘤效应及较弱的毒副作用，为开发肿瘤血管成像核素探针及受体放射治疗新药奠定了基础。3、GEBP11具有抑制胃癌血管生成的作用，这可能通过抑制ECs增殖、基质降解及迁移、粘附能力实现。

The bcl-2/bax of Safflor group treated before ICH 24 hours ahead,after ICH 0 hour were lower than that of Safflor group treated after ICH 6,12 or 24 hours. When the treated group were injected Safflor after ICH 6,12,24 hours,The number of caspase-3 positive cell around

在不同时间给予红花注射液治疗脑出血大鼠，均能不同程度地促进脑出血大鼠神经功能的恢复，其中术后6h给药组治疗效果最好，其可能通过促进Bcl-2蛋白的表达，抑制Bax和Caspase-3蛋白的表达，从而抑制血肿周围的细胞凋亡。

When the treated group were injected Safflor after ICH 6,12,24 hours,The number of caspase-3 positive cell around hematoma was gradually increased and the number of bcl-2/bax positive cell was gradually degraded and the number of TUNEL positive cell of Safflor group treated after ICH 6 hours were less than that of Safflor group treated after ICH 24 hours.

在不同时间给予红花注射液治疗脑出血大鼠，均能不同程度地促进脑出血大鼠神经功能的恢复，其中术后6h给药组治疗效果最好，其可能通过促进Bcl-2蛋白的表达，抑制Bax和Caspase-3蛋白的表达，从而抑制血肿周围的细胞凋亡。

Results Compared with ICH model group,Safflor injection could significantly alleviate neurological system damage symptoms,heighten the ratio of bcl-2/bax,and reduce the number of caspase-3 positive cell and the number of TUNEL posit

在不同时间给予红花注射液治疗脑出血大鼠，均能不同程度地促进脑出血大鼠神经功能的恢复，其中术后6h给药组治疗效果最好，其可能通过促进Bcl-2蛋白的表达，抑制Bax和Caspase-3蛋白的表达，从而抑制血肿周围的细胞凋亡。

Therelationship between the turbulent kinetic energy and its dissipation rate,whichis widely used to parameterize the dissipation rate in turbulence closure models,is found to hold well for both reversing and rotating flows,but with differentcoefficients.Microstructure profiling measurements at two comparative stations (a deepercentral basin and a local shelf break) in the stratified Yellow Sea are analyzed,with emphasis on tidal and internal-wave induced turbulence near the bottomand in the pyenocline.The water column has a distinct three-layer thermohaline structure,consisting of weakly stratified surface and bottom boundary layers anda narrow sharp pycnocline.Turbulence in the surface layer is controlled by thediurnal cycle of buoyancy flux and wind forcing at the sea surface.while thebottom stress induced by barotropic tidal eurrents dominates turbulence in thebottom boundary layer.The maximum level at which the tidally enhanced mixingcan affect generally depends on the magnitude of the tidal current,and it canbe up to 10-15 m in the Yellow Sea.This suggests that,in the deeper regionsof the shelf seas,turbulent dissipation and mixing are very weak at the levelsbetween the near-bottom tidally enhanced layer and the pycnocline.Therefore,these levels provide a significant bottle neck for the vertical exchanges.In theshallow regions,however,the tidally-induced turbulence can occupy the wholewater colum below the pycnocline.A quarter-diurnal periodicities of the turbulentdissipation rate and eddy diffusivity are found at different heights with evidenttime lag.In the relatively flat central basin,the pycnocline is essentially non-turbulent and internal-wave activity is very weak.Therefore,vertical fluxes acrossthe pycnocline decreased to molecular levels.In contrast,internal waves of variousperiods can be always found near the local shelf break.

对强层化季节黄海两对比性站位(分别位于中央海盆区与局地陆坡区)处层化、内波以及湍流混合特征的研究结果表明：1、强层化季节的陆架海水体一般呈现显著的三层热盐结构，在水体近乎混合均匀的上混合层与潮流底边界层之间为强跃层；2、近表层水体的湍流混合强度主要由海表浮力通量的日变化与海表风强迫控制，而在潮流底边界层内，潮混合是水体热量、物质、动量与能量垂直交换的主要机制；3、潮混合影响的深度由潮流大小决定，在黄海，一般可达10-15 m，因此，在水深较深的区域，在跃层与潮混合所至深度范围的上界之间存在湍流混合非常弱的区域，这显著抑制水体内物质的垂直通量，为物质垂直交换的瓶颈，而在水深较浅的区域，潮混合影响范围可至跃层底部，因此物质在跃层以下整个水体中混合非常均匀，当跃层内间歇性强混合发生时，可以产生显著的跨跃层物质输运；4、近底潮致强湍流耗散缓慢地向上传播，底上不同深度处垂直湍扩散系数也具有显著的位相差异，且二者均随时间呈现四分之一周日周期的变化；5、在地形较为平坦的中央海盆区，内波活动非常微弱，因此跃层内湍流混合非常弱，垂直扩散系数为分子扩散水平，跨跃层物质通量受到显著抑制，而在地形变化较为显著的局地陆坡区，内波活动非常活跃，除内潮的影响外，高频内波与内孤立波的影响也很显著，因此跃层内存在很强的间歇性强混合，内孤立波存在的区域，水体湍流混合显著增强。

The results showed that the decreasing of the hardness was inhibited, the 1st fracture drop off was maintained, and those such as the production of the ethylene , the degrading of the chlorophyll, the decreasing of the titratable acid were inhibited, as well as the changing of the enzyme activities. And 1-MCP can keep a better condition of the inner structure of the tomato.

结果表明，1-MCP的处理减缓了硬度的下降，在一定程度上可以保持果实的脆度，抑制乙烯生成，阻止叶绿素的降解，降低可滴定酸的减少，对酶活变化起到了一定的抑制作用，同时较好地保持了番茄果肉组织结构的完整性。

In this double-blind study, 142 women with high-risk singleton pregnancies received 100 mg progesterone or placebo daily by vaginal suppository. Between 24 and 34 weeks of gestation, all subjects had uterine contraction monitoring with an external tocodynamometer once weekly for 60 minutes.

对早产的高危险孕妇来说，预防性地在阴道使用progesterone可降低子宫收缩的频率，并减少早产的发生，虽然目前我们还不清楚它的作用机转为何，但我们知道它对子宫肌肉层有2种作用：一为藉由抑制细胞质内动情素受体的取代而抑制动情素发挥作用，另一个则是经由它自身的细胞性受体而直接作用在子宫的生合成路径上。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。