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Objective:To study the antitumor effects of Sorbaria sorbifolia ethyl acetate extract and its mechanism.

目的:探讨珍珠梅醋酸乙酯提取物对S180荷瘤小鼠体内的肿瘤抑制作用及机理。

The results showed that:①The three actinomyces strains all have transparent inhibition to the five pathogenetic fungi.

结果表明:①供试放线菌对5种草莓土传病害病原菌有明显的抑制作用。

Neural cell adhesion molecule L1, discovered in the 80s, is one of the matters that can promote nerve regeneration. It can mediate the interaction of cell-to-cell and cell-to-matrix, take great efforts on neurite outgrowth and fasciculation, migration of neural cells, formation of the myelin, structure of neural trace, transmembrane signal transduction, inhibiting apoptosis of neural cells, even on immune system and formation of the tumor. Li is discovered on the mouse's Cerebellar membrane primarily. Thereafter, it also is found in post- mitotic neurons, pre- and non-myelinating Schwann cells and so on.

神经细胞粘附分子L1(L1)是80年代发现的具有促进神经再生作用的物质,它能介导神经细胞与神经细胞之间的粘附,在神经轴突的生长、聚集,神经细胞的转移,纤维髓鞘的形成,神经通路的构建及信号的转导,抑制神经细胞的凋亡甚至在免疫系统、肿瘤的发生等方面均具有非常重要的作用。L1最初是从小鼠的小脑膜中发现,后来发现在有丝分裂后的神经元,髓鞘形成前及非形成髓鞘的雪旺细胞等组织中同样存在。

"Spermatogenesis is a long and complex process controlled by multiple interacting mechanisms, and there is a general consensus on the need for FSH in the regulation of this process," write Carlo Foresta, MD, and colleagues from the University of Padova in Italy.

精子的生成是一个很长且很复杂的过程,它是由多种彼此作用的机制控制的,在这个过程中,一般都一直需要卵滤泡刺激素的作用,」意大利Padova大学的Carlo Foresta医师及其同事写道:「从睾丸细胞学分析的结果可以看到,采用100 IU剂量的重组人卵滤泡刺激素隔日使用,以刺激精子产生的过程,同时,还可以增加射出的精子的数目,并加强抑制素B的分泌。

These results suggest that in the central nervous system of small mammals, AP waveforms mature rapidly in many types of neurons, thus, coordinated activities in neuronal circuits may occur. In early postnatal development, GABA receptor mainly mediates an excitation effect, depolarizes P6 MGBv neurons and dramatically increases the frequency of AP firing. Inhibition of GABA receptor matures slowly along with increment of postnatal days.

结论大鼠MGBv神经元的AP波形成熟较快,可在中枢神经系统的神经元环路中产生协调性的活动;在MGBv神经元发育早期,GABA主要作为兴奋性神经递质而发挥作用,它可使P6的MGBv神经元产生去极化,AP发放频率显著增加,随着出生后日龄的增加,GABA受体的抑制作用才逐渐发育成熟。

In addition, it was also found that the sulfated α-D-1, 3-glucans with higher degree of substitution had suppressive effects on dimethylbene-induced ear shell swell of mice, and possessed antivirus (HSV-1 and Influenza A) activities in vitro, suggesting that the sulfated glycans have potential usages in the release of inflammation of nerve system and the infection of some virus.

另外,还发现,具有较高取代度的硫酸化灵芝多糖对二甲苯诱导的小鼠耳壳肿胀,单纯疱症病毒(HSV-1)对Vero细胞的感染及A型流感病毒对MDCK细胞的感染均有一定的抑制作用,说明硫酸化灵芝多糖对神经系统炎症及病毒感染具有潜在的治疗作用。

Methods:(1) Dissoluble PGN and CpG DNA were immobilized onto the surface of biotin cuvette for establishing target. Another effective tracking approach was established by immobilizing Escherichia lipid A F583 onto the surface of Non-derivatised cuvett. The biosensor technology was applied to screen anti-inflammatory TCM targeting on three key molecules.(2) The active compositions were isolated by AB-8 macroreticular resin from lycium bark. After the activities of compositions were evaluated, the most effective compositions was confirmed. In vitro, the affinities of different concentrations composition E binding with PGN, CpG DNA and lipid A were measured separately. The effect of composition E on vigor of RAW264.7 cells were tested by MTT and CCK-8, and its inhibition on TNF-α, which was released from RAW264.7 cells induced by PGN, CpG DNA and LPS, was also tested by ELISA. In vivo, murine sepsis models were made by intravenously heat-killed E.coli and heat-killed S.aureus, then protection of composition E on mice sepsis model were observed.

(1)将PGN及CpG DNA包被于生物素样品池,将lipid A包被于非衍生样品池,分别建立以PGN、CpG DNA及lipid A为靶点的技术平台,对114种抗炎中药水提物进行筛选、评价其活性物质含量,并评估出针对上述三种病原分子均具有较高结合活性的中药;(2)利用生物传感器跟踪检测技术、大孔吸附树脂分离技术,从地骨皮中定向分离与PGN、CpG DNA及lipid A均具有较高亲和力的活性组分;在体外实验中,测定不同浓度活性组分与PGN、CpG DNA及lipid A亲和力;MTT法及CCK-8法检测活性组分对RAW264.7细胞活力的影响;ELISA法检测活性组分对PGN(2μg/ml)、CpG DNA(10μg/ml)及LPS(100ng/ml)刺激小鼠RAW264.7细胞分泌TNF-α的抑制作用;在体内实验中,采用尾静脉注射致死剂量热灭活大肠杆菌和热灭活金黄色葡萄球菌,建立细菌脓毒症小鼠模型,观察活性组分对脓毒症模型小鼠的保护作用。

Greenhouse pot tests showed that treatments with GJ23,NJ08 and NJ28 have greatly inhibited gall formation on tomato roots.

用GJ23,NJ08和NJ218的菌悬液进行的温室盆钵实验,结果表明不同的浓度处理均对番茄上南方根结线虫的根结形成有显著的抑制作用,其中2倍菌液处理的平均根结数比对照分别少51.4%、62.5%和54.5%;它们还对番茄的生长有明显促进作用,2倍稀释菌液处理组的番茄冠重分别比对照高39.8%、32.0%和60.5%。

Results showed that low contents of Cd has promotion effect on Oryza Sativa, but high contents of Cd has not obvious restrain on it. The total trend of distribution of Cd in Oryza Sativa is root>stem>shell>rice. The relation between Cd contents in rice and total Cd in soil as well as availability Cd in soil has been investigated. The result showed that both the total Cd and the availability Cd had notably correlation with content of Cd to rice, and the critical point were CaCl2-Cd=0.71mg/kg, DTPA-Cd=1.34 mg/kg, EDTA-Cd=0.76 mg/kg, NH4OAc-Cd=0.77 mg/kg.

研究表明:低浓度的镉对水稻生长稍有促进作用,高浓度的镉对其生长并没有明显的抑制作用;镉在水稻植株中总的分布趋势为根>茎>稻壳>糙米;用4种有效态提取剂(0.1 mol/L CaCl2、DTPA、0.05 mol/L EDTA和1 mol/L NH4OAc)浸提出的有效态镉的含量和土壤中镉总量与水稻糙米中镉含量均达到显著相关水平,并确定了它们的临界值分别为CaCl2-Cd=0.71 mg/kg, DTPA-Cd=1.34 mg/kg, EDTA-Cd=0.76 mg/kg, NH4OAc-Cd=0.77 mg/kg。

Further analysis of each question item reveals that pictures in both videos can direct and delegate attention to key linguistic features, with documentary pictures playing a more significant role than paralinguistic features in talkshows, whereas recalling and internalization of linguistic input without corresponding video hints are hindered.

对受试理解和记忆过程的分步分析发现视频有指引和分配注意力的作用,内容视频中的相关图片和场景视频中的非语言特征对理解和提取关键词汇都有不同程度的积极影响,但视频对与画面无关的听觉输入则有抑制作用。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。