抑制作用的

The results showed that the Lactobacillus acidophilus played some roles in inhibition of common pathogens of cow endometritis and adhesion to cow endometrial epithelial cell.The optimal culture temperature was 39 ℃.The strain ...

结果表明该菌最适培养温度为39℃，在偏于厌氧的环境下生长最佳，在培养18~20 h后收获最佳，对奶牛子宫内膜炎常见病原菌具有一定的抑制作用，并与奶牛子宫内膜上皮细胞具有一定的黏附作用。

Result Galium aparina water extract had some effects on the germination rate, roots length, stem length and fresh weight. The water extract decreased the germination rate and roots length of the 3 vegetables, but its effects on the stem length and fresh weigh was variable in different species.

结果］猪殃殃水提液对3种蔬菜的发芽率、根长、茎长、鲜重都有一定的影响；对发芽率、根长均表现为抑制作用，对茎长和鲜重的化感作用则因物种不同而不同。

Integrifolia lectins was slightly greater when mucus from infected fish was used, suggesting an increase of mannose and galactose binding lectins in fish skin exposed to parasites. As mannose, galactose and lactose are present on the glycocalyx of Gyrodactylus derjaini, it is suggested that lectins could play a dual role in interactions between fish hosts and their monogenean parasites.

integrifolia凝集素的抑制作用稍微更强，表明鱼类感染寄生虫后，皮肤中会与甘露糖和半乳糖结合的凝集素有所增加，由于甘露糖、半乳糖和乳糖存在于Gyrodactylus derjaini的外被多糖中，表明凝集素在鱼类寄主与单殖寄生虫相互作用中起双重作用。

Integrifolia lectins was slightly greater when mucus from infected fish was used, suggesting an increase of mannose and galactose binding lectins in fish skin exposed to parasites. As mannose, galactose and lactose are present on the glycocalyx of Gyrodactylus derjavini, it is suggested that lectins could play a dual role in interactions between fish hosts and their monogenean parasites.

integrifolia凝集素的抑制作用稍微更强，表明鱼类感染寄生虫后，皮肤中会与甘露糖和半乳糖结合的凝集素有所增加，由于甘露糖、半乳糖和乳糖存在于Gyrodactylus derjavini的外被多糖中，表明凝集素在鱼类寄主与单殖寄生虫相互作用中起双重作用。

The process of osteoarthritis mesochondrium degradation is possibly attributed to the synergistical consequence of MMPs and other factors. Pilose antler peptide can promote the proliferation of OA chondrocytes of rabbits ,inhibit the overexpression of MMPs of OA chondrocytes.It can possibly play a effective role in the treatment of OA.

结论骨性关节炎软骨细胞在骨性关节炎发病过程中，软骨细胞正常分化及增殖发生改变；骨性关节炎软骨基质降解过程可能是金属蛋白酶与其它因子协同作用的结果；鹿茸多肽可促进骨性关节炎软骨细胞增殖，并可抑制骨性关节炎软骨细胞中金属蛋白酶的过度表达，可能对治疗骨性关节炎有较好的作用。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

Methods The effects of Wuweizi Ningshen Oral Liquid on sedation,hypnotics and anti-convulsion in mice were observed by counting spontaneous behavior,prolonging sleeping time cooperated with pentobarbital sodium and antagonizing convulsion induced by Nikethamide injection.

采用镇静、催眠、抗惊厥实验观察五味子宁神口服液对小鼠自主活动的影响，协同戊巴比妥钠对小鼠的催眠作用及对小鼠尼可刹米惊厥的抑制作用。

MethodsThe effects of Wuweizi Ningshen Oral Liquid on sedation,hypnotics and anti-convulsion in mice were observed by counting spontaneous behavior,prolonging sleeping time cooperated with pentobarbital sodium and antagonizing convulsion induced by Nikethamide injection.

方法采用镇静、催眠、抗惊厥实验观察五味子宁神口服液对小鼠自主活动的影响，协同戊巴比妥钠对小鼠的催眠作用及对小鼠尼可刹米惊厥的抑制作用。

Bacillus subtilis str. B5423, Pseudomonas fluorescens str. Pf7-14, nonfluorescent pseudomonads str. P13 are antagonistic to rice sheath blight. Resistance to antibiotic is the character that was chosen to use to mark the strains in order to monitor the population dynamics of the strain on the surface of rice plant and to elucidate the mechanism of suppressing the diseases.

中文题名拮抗细菌的生态学及其对水稻纹枯病的抑制作用副题名外文题名 Ecology of biological control agents and their suppressive effect on rice sheath blight 论文作者李湘民导师许志刚教授苗东华博士学科专业植物病理学研究领域\研究方向植物病害生物防治学位级别博士学位授予单位南京农业大学学位授予日期2002 论文页码总数116页关键词纹枯病拮抗细菌水稻馆藏号BSLW /2003 /S435 /19 Bacillus subtilis B5423，Pseudomonas fluorescens Pf7-14，和非荧光假单胞肝菌Pseudomonas sp.P13是对水稻纹枯病菌有拮抗作用的三支细菌菌株。

Results showed that, pyrolin had obvious action on two species of fungi, and the antifungal effect was positively correlative with concentration. The EC50 was 0.4076 mg/mL and 0.4626 mg/mL respectively after cultured 3 days. The main antifungal period was the fast growth period of fungi, and lead to it lag behind. Observation under SEM revealed that pyrolin caused a series of marked morphological and structural alterations of hyphal. These changes included mutual adhesion of mycelium, the hyphal was irregular in diameter, local denting, some of mycelium was broken, disruption of cell wall, outbreaking of inner cytoplast, and the empty cavity appeared. As a result, pyrolin restrained the growth of these fungi.

结果表明，鹿蹄草素对上述两种真菌均具有明显的抑制作用，抑菌效果与浓度呈正相关，培养3d时的EC50分别为0.4076、0.4626 mg/mL；抑菌时期主要是在真菌的快速生长期，使其快速生长期滞后；扫描电镜显示，鹿蹄草素作用下菌体形态发生异常变化，表现为菌丝体之间相互粘连，菌丝粗细不均匀，细胞壁破裂，局部凹陷，部分菌丝断裂，大量内容物外溢，出现空腔等现象，从而发挥其抑菌作用。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。