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ResultsLoureirin B inhibits the TTXR peak sodium currents in a dose-dependent model and the inhibition is reversible. 0.2mmol/L loureirin B accelerates the inactive process of the TTXR sodium currents and delays the revivable process but does not affect the activitive process.

结果龙血素B对TTXR钠电流呈浓度依靠性抑制,且抑制作用可逆;高浓度的龙血素B(0.2 mmol/L)加速TTX-R钠通道电流的失活过程,延迟其复活过程,对激活过程无显著影响。

Qinghao acid, Qinghao B, Scopoletin, Casticin and Chrysosplenol D had some antimalarial activities on P. berghei. Even when the dosage was up to 500 mg/kg/d, the maximal inhibition rate was only 59%, which is less active than QHS. Therapeutic effect of different ingredients of A.

青蒿酸、青蒿乙素、东莨菪内酯、青蒿黄酮1、青蒿黄酮2 5种成份对鼠疟均有不同程度的抑制作用,但剂量高达500mg/kg/d时,抑制率最高也仅达到59%,远低于QHS的疗效。

The influence of dizocilpine on the convulsions induced by semicarbazide in mice were also observed. Results: Dizocilpine (0.05-0.25 mg-kg-1, ip) dose-dependently inhibited the amygdala kindled seizure, shortened the afterdischarge duration and reduced the Racine's stage P

MK-801对大鼠杏仁核点燃有抑制作用,与苯巴比妥钠、丙戊酸钠、第一章中文摘要尼卡地平联合应用有协同作用,其机制与增强GABA系统功能以及c扩十拮抗有关,该研究为临床合理用药,尤其是联合用药治疗癫痈提供新的依据。

MATERIALS AND METHODS: Cytotoxicity of the drugs was measured by MTT assay. The coefficient of drug interaction was used to analyze the synergistical suppressive effect of drug combination.

材料与方法:采用MTT法测定不同浓度氯化镉和顺铂对人肝癌细胞SMMC-7721增殖的抑制作用;应用两药相互作用指数进行联合作用分析。

Department of Toxicology, Shenzhen Center for Disease Control and Prevention, Shenzhen 518020, Guangdong,China

背景与目的:探讨5-氮杂胞苷对人乳腺癌细胞Bcap-37细胞增殖的抑制作用及作用机制。

Low contents of Cd has promotion effect on the growth of triticum aestivum,but high contents of Cd has obvious restrain on it.

研究表明,低浓度的镉对小麦生长稍有促进作用,而高浓度镉对小麦生长有明显抑制作用。

Veratryl alcohol could stimulate the oxidation of PR catalyzed by LiP, especially at higher molar ratios of H2O2 to PR, however, PR inhibited the LiP catalyzed oxidation of VA.

藜芦醇对LiP催化氧化PR的反应有促进作用,尤其是当H202与PR的摩尔比较高时这种促进作用更为明显;然而PR对LiP催化氧化VA的反应却有抑制作用。

Further, we found that phenytoin couldn't inhibit the LPS-induced IkappaB-alpha degradation suggesting that this drug might not affect LPS-induced activation of NF-kappaB by abrogating the LPS-induced IkappaB-alpha?ndegradation.

在机转方面,我们证实phenytoin并不能有效抑制经LPS活化所造成ΙκB-α的降解,因此,我们推论phenytoin的抑制作用可能不是经由NF-kappaB这条路径。

Objective To evaluate effect of hemagglutinating virus of Japan -liposome mediated tissue factor pathway inhibitor gene transfer on neointimal hyperplasia of endothelium denuded carotid artery of rat.

目的 探讨日本凝血病毒-脂质体介导的组织因子途径抑制剂基因转移对大鼠颈总动脉内皮剥脱术后新生内膜增生的抑制作用。

Whenadministrated to rings precontracted with 1μmol·L-1 PE in the absence ofextracellular Ca2+, a second extracelluar-calcium-dependent vasoconstrictioninduced by restoration of extracellular Ca2+ were also reduced by pretreatment of 50-200μmol·L-1 MLB dose-dependently.

在复钙实验中观察到,MLB 50-200μmol·L-1 不仅抑制PE 1μmol·L-1 诱导的内钙依赖性血管收缩,而且对复钙后外钙依赖性的血管收缩也有抑制作用。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

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There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。