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Result: In contrast to the controls, the expressions of the CD3, CD25, CD25 on CD4+, CD8+ lymphocytes were statistically decreased(P<0.05) in both serious and nonserious AA.

结果:再障试验组与对照组相比,重型再障和非重型再障患者骨髓CD3+、CD25+比值、CD4+和CD8+细胞中CD25+细胞比值均明显减低(P<0.05),CTLA4Ig对重型再障的抑制作用高于非重型再障,对CD4+细胞的抑制作用高于CD8+群体。

RESULTS:Using nubilous inhalation or intragastric administration,artesunate significantly inhibited the guinea-pig model asthma in a dose-dependent manner.Its ED50 were (99.95±7.69)mg.L-1(n=4) and (15.64±1.25)mg.kg-1.d-1(n=4) respectively.

结果:雾化或灌胃给药,青蒿琥酯均对药源性哮喘呈现剂量依赖性明显的抑制作用,其半数有效剂量(ED50)分别为(99.95±7.69)mg.L-1(n=4)和(15.64±1.25)mg.kg-1.d-1(n=4),其抑制作用与给药的剂量之间呈良好线性关系。

PPARα ligands suppressed OPN promoter actiity, and an actiator protein-1 consensus site conferred this repression. Oerexpression of c-Fos and c-Jun reersed the inhibitory effect of PPARα ligands on OPN transcription, and, in chromatin immunoprecipitation assays, PPARα ligands inhibited c-Fos and phospho–c-Jun binding to the OPN promoter.

PPARα配体可抑制OPN启动子活性,一个激活蛋白-1的一致序列位点与这种抑制有关。c-Fos和c-Jun的过表达可逆转 PPARα配体对OPN转录的抑制作用,并且在免疫沉淀实验中,PPARα配体可抑制c-Fos及磷酸化c-Jun与OPN启动子的结合。

These results indicate that the brain endogenous opioid system seems to play a major role in the modulation of the micturition threshold and the frequency, whereas in the spinal region, enkephalinergic neurons seem to control the activity of sacral preganglionic neurons.

这些结果显示,脑部之内吗啡系统的抑制作用,主要和排尿反射阂值之调控有关,而脊髓部位的内吗啡系统则可直接对副交感神经节前神经元造成抑制性作用。

Methods:Alpha-glucosidase activities were examined with or without Folium Mori alkaloids extract,Ramulus Mori extract and acarbosein vitro, and the IC_(50)were calculated.

本文以拜糖平为阳性对照,采用α-葡萄糖苷酶体外抑制作用实验,比较了桑叶生物碱浸膏、市售的桑枝提取物以及拜糖平对α-葡萄糖苷酶的抑制作用能力差异。

The change of GR plays an impor trant role in low suppressive effect of PLA2.There was a negative correlation between PLA2 and GR from early stage to 72 hours after injury. The suppressive effect of glucocorticoid to PLA2 is relative to GR.

2GR减少是PLA2抑制作用低下的重要因素,早期至72hPLA2与GR改变呈负相关,糖皮质激素对PLA2 的抑制作用与GR水平密切相关。

Results The compositions of 28 Chinese herbs can inhibit the growth of 5 bacteria in different levels, but the effects on other 3 bacteria are not obvious. Quercetin and usnic acid have better effects on 5 bacteria than other 26 herbs compositions, with MIC 0.03125~0.125mg/ml and 0.0156~0.0625mg/ml.

结果 28种中药有效成分对3种牙周细菌抑制作用不明显,对另5种口腔常见细菌有一定的抑制作用,其中松萝酸和槲皮素有较强的抑菌作用,MIC值分别在0.0156~0.0625mg/ml和0.3125~0.125mg/ml之间。

The inhibition effect of chloroform fraction was the most potent, with the inhibition rate about more than 83% to 5 plant pathogenic fungi under the concentration of 15mg/mL. Under the concentration of 15mg/mL, the ethyl acetate fraction and n-butanol fraction thoroughly inhibited the growth of Alternaria solani and Valsa mali, with the inhibition rate up to 100%. The n-butanol fraction showed the highest potent virulence, with EC50 to Alternaria solani and Valsa mali about 0.09 and 0.279 mg/mL respectively.

其中氯仿部分的抑菌效果较好,当质量浓度为15mg/mL时,其对5种植物病原菌的抑制率均在83%以上;15mg/mL乙酸乙酯部分和正丁醇部分分别对番茄早疫病菌和苹果腐烂病菌有强烈且稳定的抑制作用,抑制率达100.00%,正丁醇部分对这两种菌丝生长抑制毒力最好,EC50分别为0.090和0.279mg/mL。

The inhibitory effect of the volatilizable metabolites of two antagonists to P.funerea was analyzed in contrast with the inhibitory rate of the control . Gvirens , with the highest inhibitory rate of 59.7%, had more excellent and stable inhibitory activity and the effect was more relative with the time, but the inhibitory rate of B.firmus was less relative with the time and the inhibitory effect of B.firmus became stable after 72 hours.

两种颉抗菌代谢物中不同成份的抑菌效应试验表明,G.virens产生的多糖、粗脂肪、蛋白质对P.funerea孢子萌发有抑制作用,粗脂肪、蛋白质更明显,其中蛋白质抑制效果较稳定;B.firmus产生的粗脂肪可完全抑制P.funerea的孢子萌发,多糖、蛋白质抑制效果也较稳定,但多糖效果更好。

The agglutinating activity could be inhibited by the splitting of lactose and sucrose. The results demonstrated the sugar referred above played an important role in agglutinating reaction.

经糖的专一性抑制实验显示,蔗糖和乳糖对凝集反应有抑制作用,说明这2种糖分子是凝集素在识别和凝集过程中起一定作用的糖分子。

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