抑制作用的

However, dexamethasooe did not seem to affect the sustained current and the sustained component of the biphasic current induced by ATP. The in hibitory effect of dexamethasonc on ATP induced currents was blocked by glucocorticoid receptor antagonist RU38486 (10μmol/L) and protein kinase A inhibitor H-89 (10μmol/L), but not by G protein inhibitor GDP-β-S (0.2mmol/L) and protein kinase C inhibitor chelerythrine chloride (10μmol/L).

地塞米松对ATP激活电流的快速抑制作用可被糖皮质激素受体拮抗剂RU38486(10μmol/L)、蛋白激酶A抑制剂H-89(10μmol/L)阻断，而G蛋白激活抑制剂GDP-β-S(0.2mmol/L)、蛋白激酶C抑制剂Chelerythrine chloride(10μmol/L)对地塞米松的快速抑制作用无明显影响。

We show that, in primary breast tumour cells, this event causes decreased p53 levels and increased chemoresistance.

现在， NUMB 已被发现通过抑制泛素连接酶 Hdm2、从而防止主要肿瘤抑制因子 p53被破坏来起一种肿瘤抑制因子的作用。

We conclude that baicalein, wogonin and chrysin show a suppressive effect on iNOS gene expression in macrophages stimulated with LPS and the sequence of their suppressive effect intensity is chrysin, baicalein and wogonin seperately, and that it may be an important foundation for the combination therapy of TCM and Western medicine in the treatment of endotoxin-shock syndrome.

这些的发现，显示baicalein 、wogonin 和chrysin对脂多醣诱导小鼠巨噬细胞株生成一氧化氮有抑制的作用，而以。chrysin抑制作用最强，其次为baicalein 、wogonin，此结果可作为未来中西医整合治疗败血症之主要依据。

In A549 group and controling group 0.9% NS were injected to mice by abdomen respectively. In DDP group 1000uM cisplatine were injected to nude mice by abdomen which was inefficiency to A549DDP cells.

第二章 人参单体Rh2和顺铂抑制A549DDP细胞移植瘤生长的作用研究目的：探讨人参单体Rh2和顺铂对A549DDP细胞移植瘤的抑制作用。

Lagenarium was higher 60%(for example, Glycyrrhiza yralensis, Lycium barberum and Desmodium styracifolium) as the concentration 0.01g/ml. Especially, the G. yralensis showed the strongest inhibitory effect on it with inhibitory rate of 99.6%. The inhibitory rate of 12 PE against mycelium growth and 15 PE against appressorium formation of C.

供试提取物在质量浓度为0.01 g/ml条件下，甘草、枸杞、金钱草等11种植物的80%乙醇提取物对黄瓜炭疽病菌分生孢子萌发的抑制率大于60%，其中甘草的抑制作用最强，达99.6%；12种提取物对黄瓜炭疽病菌菌丝生长的抑制率大于50%；15种提取物对黄瓜炭疽病菌附着胞形成抑制率达50%。

Results Qidan Granules could relieve the pain caused by glacial acetic acid and heat stimuli; significantly inhibit the oxytocin-induced dysmenorrheal in mice; It also showed obvious inhibitory effects on the increased capillary permeability induced by glacial acetic acid, carrageen-induced toe edema in rats and dimethylbenzene-induced ear swelling in mice, and cotton pellet-induced granuloma formation in rats. It could also significantly inhibit oxytocin-induced dysmenorrhea in mice.

结果 奇丹颗粒能明显抑制乙酸和热刺激所致的小鼠疼痛反应；对缩宫素所致实验性痛经小鼠具有良好的镇痛作用，对乙酸所致小鼠腹腔毛细血管通透性增高以及大鼠角叉菜胶足趾肿胀、二甲苯所致小鼠耳廓肿胀、大鼠棉球肉芽肿等急慢性炎症模型均有明显抑制作用。

The inhibitory potency of geranyl gallate is as about six times as that of lauryl gallate on mushroom tyrosinase. Lauryl gallate was determined to be an uncompetitive inhibitor while geranyl gallate belongs to be a mixed-type inhibitor.

没食子酸香叶酯对蘑菇酪氨酸酶的抑制作用比没食子酸十二烷基酯更强，没食子酸十二烷基酯表现为反竞争性抑制类型，而没食子酸香叶酯表现为混合型抑制类型。

Result3 strains of endophytic fungi had growth peak when the pH value was 6.5-7.5,and could grow within pH of 4.0-8.5. Their acid-alkali adaptability was strong,in which the P-3 adaptability was the strongest. P-1and P-2 had the stronger inhibition to the Bacillus subtilis,Escherichia coli and Staphylococcus aureus,and P-3 only had the little inhibition to Escherichia coli. The 3 endophytic fungi all had inhibitory effect on Podosphaera leucotrlcha,Alternaria mali,and Gymnosporangium yamadae Miyabe,in which,P-1 had the better inhibitory ability.

结果3株内生真菌在pH值6.5～7.5出现生长最高峰，在pH值4.0～8.5都可以生长，酸碱适应性很强，其中P-3的适应性最强。P-1和P-2对枯草芽孢杆菌、大肠杆菌、金黄色葡萄球菌都有较强的抑制能力，而P-3只对大肠杆菌有很微弱的抑制能力。3株内生真菌对苹果锈病病原菌、苹果白粉病病原菌、苹果落叶病病原菌都有抑制作用，其中P-1的抑制能力较强。

The advance research of international and domestic natural sweetness inhibitor were summarized, mainly focused on the components and functions of three plants:Gymnema Sylvestre, Ziziphus jujuba and Hovenia dulcis Thunb.

对国内外天然甜味抑制剂的研究进展进行了综述，重点对含有天然甜味抑制成分的 3种植物———匙羹藤、大枣和枳橘的甜味抑制成分及其作用进行了阐述，为进一步研究和开发利用天然甜味抑制剂提供参考。

GABA inhibited the spontaneous contraction of mouse ileac smooth muscle, this inhibitory effect is influenced by NO and the excitation ofβ-receptor. But the effect is independent of the Cl- channel that gated by GABAA receptor.

GABA对小鼠回肠自主收缩主要起抑制作用，这种抑制作用与GABAA受体所介导的Cl-通道无关，而受NO和β-肾上腺素能受体活动的影响。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。