抑制...

Results The expression of TNF-α in HBE was activated by sputa from bronchiectatic patients and Zhikuoning Mixture might su...

结论支气管上皮细胞TNF-α表达在支气管扩张症发病中可能起到重要的作用；中药支扩宁合剂可抑制支气管上皮细胞TNF-α的表达，从而抑制支气管扩张症气道炎症反应，这可能是其疗效机理之一。

The MTT assay was used to detect the viability of cells. Flow cytometry and laser confocal microscopy were used to identiyfy the cell cycle and apoptotic morphology after cells treated with LAO. RESULTS: An L-amino acid oxidase was successfully purified from the venom of bungarus fasciatus.

结果： 通过两步层析法从金环蛇毒中分离得到L-氨基酸氧化酶，L－氨基酸氧化酶的表观分子量通过SDS-PAGE测定约为60 kD，通过凝胶过滤测定分子量为70 kD.L－氨基酸氧化酶作用于HUVCE细胞12 h后，细胞的生长明显受到抑制，L－氨基酸氧化酶作用的半数抑制量为2.8 mg/L。

The models of auricular edema in mice by dimethyl benzene and increased permeability of celiac blood capillary by acetic acid were studied,the results showed that the petroleum ether and acetic ester fraction of fermentation product of Calvatia gigantea could inhibit ear edema;acetic ester and n-Butanol fraction of fermentation product could reduce the permeability of celiac blood capillary by acetic acid.

大秃马勃Calvatia gigantea发酵液的石油醚、乙酸乙酯和正丁醇提取物进行二甲苯诱导小鼠耳廓急性炎症和醋酸所致小鼠腹腔毛细血管通透性实验，结果表明大秃马勃Calvatia gigantea发酵液石油醚提取物处理组、乙酸乙酯提取物处理组对二甲苯诱导小鼠耳肿胀具有明显的抑制作用；大秃马勃Calvatia gigantea发酵液乙酸乙酯提取物处理组、正丁醇提取物处理组对醋酸所致小鼠腹腔毛细血管通透性具有明显的抑制作用。

Fluid of profess to convinced of glue of result compound bee can restrain the formation of reserpine ulcer significantly, the heal of acerbity to second burn ulcer has apparent stimulative effect, can restrain the formation of pylorus ligate ulcer significantly, reduce cankerous area significantly, its action and positive contrast medical Xi Mi comparatives for man.

结果复方蜂胶口服液可显著抑制利血平溃疡的形成，对乙酸烧灼型溃疡的愈合有明显的促进功能，可显著抑制幽门结扎溃疡的形成，并显著减少溃疡面积，其功能和阳性对照药西咪替丁相当。

Methods:The proliferation inhibition of cantharides injections on LoVo cells were detected by tetrazolium.Annexin V-FITC were applied to study cell apoptosis of LoVo cells.FCM were applied to detect the expressions of the Fas and Bcl-2 protein.Results:Cantharides iniections could inhibit the proliferation of LoVo cells and could couse cell apoptosis.

四甲基偶氮唑盐测定药物对LoVo细胞抑制作用与时间和剂量的关系，Annexin V-FITC方法对细胞凋亡进行检测，流式细胞术检测细胞Fas、Bcl-2蛋白表达水平结果：MTT实验表明复方斑蝥注射液可抑制LoVo细胞的生长并诱导发生凋亡。

AA inhibits capacitative Ca2 entry: The mechanism underlying this effect of AA is likely due to the activation of protein kinase C by AA.

AA抑制容积性钙内流：其机制与AA激活蛋白激酶C，后者通过某些未知机制抑制容积性钙内流有关。

Their relative molecular weights were 4785 and 4386 respectively. And their absorbance peaks were 210.5 nm and 225.4 nm respectively. The bovine and caprine placental peptides could improve immunosuppressive T lymphocyte transformation rate. The immunosuppressive lymphocyte transformation rates in groups with the bovine placental peptide of 1:1×10^3 and 1:1×10^4 (P.05)and with the caprine placental peptides of 1:1×10^2, 1:1×10^3 and 1:1×10^4 (P.01 )increased more remarkably than that in immunosuppression group.

结果 从牛和羊胎盘中成功提取出了胎盘肽，其相对分子质量分别为4785和4386；其最大吸收峰分别为210.5和225.4nm；牛和羊胎盘肽均可使顺铂抑制的兔外周血T淋巴细胞的转化率显著提高，其中牛胎盘肽以1：l×10^3、1：l×10^4 2组吸收度明显高于抑制组(P.05)；羊胎盘肽以1：1×10^2、1：1×10^3和1：1×10^3 3组效果最为明显(P.01)。

MethodsThe distilled bovine and caprine placental peptide s were prepared by ultrafiltering and their relative molecular weights were mensurated by improved Tricine-SDS-PAGE eletrophoresis with urea.

结果从牛和羊胎盘中成功提取出了胎盘肽，其相对分子质量分别为4 785和4 386；其最大吸收峰分别为210.5和225.4 nm；牛和羊胎盘肽均可使顺铂抑制的兔外周血T淋巴细胞的转化率显著提高，其中牛胎盘肽以1∶1×103、1∶1×1042组吸收度明显高于抑制组(P.05)；羊胎盘肽以1∶1×102、1∶1×103和1∶1×1043组效果最为明显(P.01)。

In order to overcome the problem of multidrug resistance in human epidemic carcinomata anti-adriamycin cells (KB-A-1), the antisense and antigene oligonucleotides were used to investigate their effectiveness on inhibiting the mdr1 gene expression. The effectiveness of antisense or antigene oligonucleotide on inhibiting the multidrug resistance was detected by MTT colometric assay and ELISA.

中文题名反义与反基因寡核苷酸及其萘二酰亚胺偶联物对靶基因表达的抑制作用研究副题名外文题名 The inhibition of the targeted gene expression by the antisense or antigene oligonucleotides and their naphthylimide-conjugated derivatives 论文作者李军生导师张元兴魏东芝教授学科专业生物化工研究领域\研究方向生物化学与分子生物学学位级别博士学位授予单位华东理工大学学位授予日期2001 论文页码总数106页关键词基因表达基因治疗反义寡核苷酸反基因寡核苷酸核酸馆藏号BSLW /2001 /Q78 /264 针对人表皮癌抗阿霉素细胞株（KB-A-1）的多药抗药性问题，本文从反义核酸和反基因核酸角度，通过MTT法检测细胞生长情况，ELISA法检测基因表达产物P-gp表达水平的变化，对寡核苷酸抑制肿瘤细胞MDR1基因表达的机制进行了探讨。

In both normal and carcinomatous cells, the activity of this enzyme decreased under the inhibitor treatment, bowever, PARP in carcinomatous cells is more sensitive to inhibitor.

实验结果表明，正常细胞和癌变细胞PARP酶在抑制剂作用下酶活性都会降低，但是癌变细胞的PARP酶对抑制剂更为敏感。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。