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Researchs suggested that ceramide and sphingosine could inhibit mitosis and DNA synthesis of cancer cells, promote apop
细胞水平研究发现神经酰胺和鞘氨醇能抑制结肠癌细胞有丝分裂和DNA合成,促进细胞凋亡,影响Fas、Bcl-2、Bcl-10、bax和P53等凋亡相关蛋白的表达,即神经酰胺和鞘氨醇能通过抑制结肠癌细胞生长、促进细胞凋亡发挥抑癌作用。
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During these years (1997-2000) in the research area of annonaceous acetogenins 5 natural products and a number of chiral-pure analogs of annonaceous acetogenins have been synthesized using sugars as the starting materials. Their high activity and selectivity against cell line of colon tumor and a relationship between activity and configuration have been found too. In the respect of inhibitor of sialidase two new methodologies for the synthesis of chiral-pure 3-deoxy-ulosonic acid using hetero-Diels-Alder reaction or asymmetric propargylation as the key reaction were developed. On the topic of anti-leukemia marine natural product clavulactone a synthetic method based on the free radical cyclization and starting from sugar has been developed. In other title of PKC inhibited agent sphingosine a new synthetic route with SN2' as the key reaction has also been disclosed.
项目期间(1997-2000)在番荔枝内酯方面从糖出发合成了五个天然产物和一批手性纯的类似物,它们对肠癌细胞有很高的活性和选择性,并与构型有关;在唾液酸酶抑制剂方面发展了二类全新手性纯高碳糖的合成方法-杂原子D-A反应或丙炔基不对称加成为关键的反应;抗白血病海洋天然产物群柱虫内酯方面研究了由糖出发和自由基环化反应的合成方法;对PKC 起抑制作用的鞘氨醇方面也开创了新的合成途径-由糖出发并以SN2'反应为关键反应。
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2PKC inhibitor—staurosporine or sphingosine could also inhibitthe stimulatory effect of FSH(100IU/L);while PKC activator,phorbol myristate acetate,at the concentration of 10-8-10-5M had a dual effect on the meiotic resumption of pig CEO.
2PKC的抑制剂——Staurosporine(10-9-10-6M)或Sphingosine(10-8-10-5M)也能够显著抑制FSH(100IU/L)的刺激作用;然而PKC的激活剂——PMA(10-8-10-5M)对猪CEO减数分裂的恢复具有双相作用。
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Red grape wine with its resveratrol could inhibit carcinoma has the effects on preventing neuropathic diseases like senile dementia and Parkinson′s disease etc. and inhibiting proliferation of spirochaete.
红葡萄可抑制螺旋菌的增殖,有抗肿瘤作用,其中含有白藜芦醇,有抑制癌的效果,可防止老年性痴呆、泊金森氏综合症等神经性疾病。
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Eggs and soyabean milk contains soap protein enzyme stayer,which can control liveness of flesh's protein enzyme,affecting protein digestion and absorption internal to the body.Egg white contains tough protein,which can integrate with soap protein enzyme in the soybean milk,blocking the break down of protein,thereby reducing the protein absorptivity of the body.
鸡蛋与豆浆生豆浆中含有胰蛋白酶抑制物,它能抑制人体蛋白酶的活性,影响蛋白质在人体内的消化和吸收,鸡蛋的蛋清里含有粘性蛋白,可以同豆浆中的胰蛋白酶结合,使蛋白质的分解受到阻碍,从而降低人体对蛋白质的吸收率。
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Evaluating the effect of the addition of tannin in the stillage and brewing water,the rate of 6g/hl in stillage water and 10g/hl in brewing water under pH 5.3 and 62℃ can be in favor of wort filtrition, restrain LOX reaction, reduce the aldehydes concentration in the wort, enhance the deoxidization, restrain the oxidation of lipid and protein to enhance t...
1在洗糟水加6g/hl,酿造水加10g/hl的单宁,控制pH5.3,温度62℃,既有利于麦汁的过滤、抑制LOX反应、降低麦汁醛类浓度、增强啤酒的还原力,又能抑制脂肪和蛋白质氧化,提高啤酒的风味稳定性。
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The shuangxiangyou preparation extracted from the levant storax oil and the dalbergiae odoriferae oil has significant pharmacological action on the disease of cardiovascular system ,such as anti-myocardial ischemia,anti-platelet aggregation and an-ti-thrombogenesis, et cetera.
苏合香和降香两种药物提取出的双香油对抗心肌缺血、抑制血小板聚集以及抑制血栓形成等心血管疾病系统疾病方面有着重要的药理作用。
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After pretreatment with TFP, although the conductance of cultivate solution of strawberry seedling under NaCl stress was not increased, growth was inhibited obviously by TFP, while the leaf relative electric conductivity in strawberry increased, leaf holding ability was reduced. The inhibiting response increased with the concentration of TFP increasing. On the contrary, conductance in cultivate solution was increased by Ca(NC?3)2 treatment, but the leaf relative electric condu
用Ca(NO_3)_2和TFP培养处理NaCl胁迫的草莓幼苗,发现TFP培养处理虽然不增加培养液的电导值,但明显抑制盐胁迫草莓幼苗的生长,增加了叶片膜透性,降低了叶片保水力,抑制作用随TFP浓度的增加而增大;而Ca(NO_3)_2处理虽然增加了培养液的电导值,但降低了幼苗叶片膜透性,提高了叶片保水力,因而减轻了NaCl
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The activity of polygalacturonase and carboxymethylcellulase of tomato and strawberry is restrained in HVEF, and therefore the soften of tomato and strawberry are restrained.
高压静电场处理可以抑制番茄和草莓果实多聚半乳糖醛酸酶和羧甲基纤维素酶活性,抑制草莓和番茄果实软化。
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The present thesis showed that root elongation of alfalfa (Medicago sativa L.) during a 24-h period was inhibited by 80% by the exposure to 5 umol L-1 Al and its roots was obviously stained by eriochrome cyanine R; however, the roots of stylo need to be exposure to 30umol L-1 Al in order to get obviously stained with its root elongation was inhibited by 68%, which shows, for stylo, its ability of tolerance to aluminum is strong.
本研究发现,5 μmol L~(-1)AlCl_3使紫花苜蓿根长抑制80.0%,铝处理后的根尖被铬天青明显染色,而柱花草经30 μmol L~(-1)的AlCl_3处理后方观察到根尖明显染色的现象,根的伸长受抑制68.0%,表明柱花草抵御铝毒能力较强。
- 推荐网络例句
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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.
此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。
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To get the business done, I suggest we split the difference in price.
为了做成这笔生意,我建议我们在价格上大家各让一半。
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After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.
一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。