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BMI-1(B-cell-specific Moloney murine leukemia virus integration site 1), a Polycomb group repressor, is always present as a PcG complex combined with RING1, HPC2, Mph2, et al. BMI-1 prolongs cells'capacity to proliferate and represses their senescence by repressing the transcription of CDKN2A through acetylhydrolasing or deacetylhydrolasing the Polycomb response elements in chromosome.

BMI-1 (B-cell-specific Moloney murine leukemia virus integration site 1)属于PcG家族,它与该家族其他成员如RING1,HPC2,Mph2等结合形成蛋白复合体,作用于染色质PREs位点,通过对组蛋白进行乙酰化和去乙酰化修饰,从而稳定抑制CDKN2A转录,最终促进细胞的增殖并抑制细胞凋亡。

On the base of the mathematic model of the PMSM, the reasons of the torque pulsation are analyzed. Then the validity of Iterative Learning Control in torque ripple minimization is expatiated. A whole simulation model is developed using SIMPOWER, and the effective of ILC in torque suppressing is proved. The scheme for hardware and software of integrated PMSM are demonstrated in the thesis.

本文在永磁同步电机数学模型的基础上,总结分析了永磁同步电机转矩脉动产生的原因,引入迭代学习控制抑制转矩脉动,利用SIMPOWER工具箱建立了永磁同步电机控制系统的仿真模型,对PMSM控制系统进行了仿真,仿真结果证明迭代学习控制能有效地抑制转矩脉动。

Meanwhile, the antibodies of VIP enhanced the activation of lymphocytes and the expression of CD68, SYP in sacculus rotundus.

采用抗SP抗体使SP作用受到抑制后,圆小囊组织中淋巴细胞活化分子、DNES细胞表达SYP和巨噬细胞表达CD68分子的量均出现一定程度的减少;而当VIP作用受到抑制后,圆小囊组织中淋巴细胞活化分子、DNES细胞表达SYP和巨噬细胞表达CD68分子的量均出现一定程度的增多。

Simulation results also show that saddle-shaped distributed AMF can more effectively inhibit constriction of vacuum arc.

对于小电流扩散态真空电弧,重点仿真分析不同电弧电流与不同纵向磁场对其关键特性的影响,部分仿真结果进行了实验验证;对离子处于超音速流动的收缩态真空电弧的仿真表明,真空电弧的磁收缩主要是由于霍尔效应引起的,离子温度和电子温度沿轴向先增大后减小,马鞍形分布的纵向磁场能够更有效地抑制真空电弧的收缩,而且阴极斑点分布对真空电弧特性也有着显著的影响;对离子处于亚音速流动状态的大电流真空电弧的仿真表明,部分等离子体不能到达阳极而损失,马鞍形分布的纵向磁场能够更有效地抑制电弧等离子体的损失,同时能使阳极电流密度和能流密度的分布更加均匀。

Yam steroid saponins and sapogenin are resulting in MCF-7 cells apoptosis by arrested the G0/G1 phase, increased the p53 protein with promoting apoptosis and decreased the AKT protein with anti-apoptosis and the BRCA-1 protein with repairing DNA. And, SPG has the excellent anti-cancer effect on MCF-7 cells may be due to induced much of the p53 protein in the early treated stage.

进一步的研究发现,山药固醇类皂及皂元抑制MCF-7乳癌细胞的功效,主要是诱发G0/G1期停滞,造成细胞凋亡;其透过的机制是经由p53促凋亡蛋白的增加,及AKT与BRCA-1等抗凋亡蛋白被抑制,达到双重细胞凋亡之抗癌效果;其中SPG处理之MCF-7肺癌细胞具早期大量诱发p53蛋白的特性,或许是SPG优异抗癌效果之原因。

The results of tissue culture show that Nicarb has inhabitation function to the first-generation schizont. Such a product also has the function of inhabitation and kill.

本品对球虫兼抑制和杀灭作用,即既有预防又有治疗作用,即使在感染48小时或72小时后投药,亦能充分抑制球虫。

Autoimmunity hypothesis of schizophrenia figures schizophrene has a certain degree of immunological functional disturbance,Hypothalmu- pituitary- adrenal axis can produceimmunosuppression. Hydrocortisone,the production of HPA axis,serve as important medium of immunosuppression, so we presume that hydrocortisone possibly induce immunological dysfunction of schizophrene.

精神分裂症的自身免疫假说认为精神分裂症患者存在一定程度的免疫功能低下,而下丘脑-垂体-肾上腺轴功能紊乱被认为是引起免疫抑制作用的主要机制之一,其中皮质醇是免疫抑制作用的重要介质,因此我们推测精神分裂症患者可能存在有皮质醇含量增高有关。

Streptomyces 702 can obviously result in condensing of the plasma in the mycelium cell and strongly inhibit sclerotium and spore germination,a complete inhibition takes place when the dosage is at the level of 15.11 mg/L and 10.64 mg/L.

能显著的引起菌丝细胞内原生质凝集;对菌核及孢子的萌发有较强的抑制作用,15.11mg/L和10.64mg/L完全抑制菌核和孢子的萌发

In order to inhibit the variation and second variation of Trypanosome, a predominant VSG antigenic reservoir has been established by purification VSG from VAT, leading to a better immune protection and overcome immune failure due to antigenic variation.

我们设想提纯全部优势变异体 VSG,建立优势 VSG 抗原库,期望该抗原库能抑制虫体变异或抑制虫体的第二次变异,从而对动物起到较好的免疫保护作用,克服因抗原变异引起的免疫失败。

Based on the inhibition ability of extracts from seed capsule and endosperm,the seven seed sources were divided into 2 and 3 geographical groups,respectively.

依据种皮浸提液的抑制能力7个种源可分为2组,而依据胚乳浸提液的抑制能力则可被分为3组。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。