抑制...

OBJECTIVE: Three sesquiterpene lactones 1-O-acetylbritannilactone, isoalantolactone and britannilactone were isolated from the roots of Inula helenium and the flowers of Inula japonica. The antitumor activities of the three sesquiterpenoids in the cell lines of HeLa, HEC-1, SHIN3, HOC-21 and HAC-2 were measured, and the relationship between structure and activity and the possible mechanisms were explored.

目的： 观察菊科植物中分离出的3种倍半萜化合物异土木香内酯、1-氧-乙酰大花旋覆花内酯和大花旋覆花内酯对体外培养的人子宫颈癌HeLa细胞、人子宫内膜癌HEC-1细胞、人卵巢透明细胞癌SHIN3及HOC-21细胞和人卵巢囊腺癌HAC-2细胞增殖的影响，研究这3种倍半萜化合物的体外抑制肿瘤细胞增殖作用及其结构与活性之间的构效关系，进而探讨3种倍半萜化合物的体外抑制肿瘤细胞增殖的可能机制。

The results indicated that the inhibited concentrations of kanamycin of adventitious bud formation of Helianthus annus were 75 mg/L and 100 mg/L, when the carbenicillin was used in the transformation procedure; the concentrations was 300 mg/L when the growth of agrobacterium could be effectively inhibited. At the same time, the induction and growth of adventitious bud were not remarkably injured.

在以卡那霉素为抗性选择标记时，对油葵不定芽起完全抑制作用的Km临界浓度在75~100 mg/L；在以羧节青霉素为抑菌剂用于油葵遗传转化试验时，其浓度为300 mg/L时即可有效抑制农杆菌的生长，同时又不会对不定芽的诱导及生长产生明显的伤害作用。

The results indicate that the growth of tumor is inhibited by means of transfusion blood with ultraviolet radiation of hematoporphyrin. The most remarkable inhibitory effect is in ultraviolet radiation and hematoporphyrin group. The generation of singlet oxygen by PDT may be one of the mechanisms of killing tumor cells.

经紫外光照射的血或含有血卟啉的血均对肿瘤生长有抑制作用，而且紫外光照射与注人血卟啉相结合对抑制肿瘤生长效果最佳，该光动力学疗法对肿瘤治疗作用机制之一可能是通过产生单态氧而杀伤瘤细胞的。

It is characterized by malignant unusual hyperplasia and soading of cells in medulla ossium and other tissues, which can damage the normal hemopoiesis function and the mechanism of blood coagulation fibrinolysis and immunology.

机体的免疫功能与肿瘤的发生和发展有密切关系，当宿主免疫功能与肿瘤的发生和发展有密切关系，当宿主免疫功能低下或受抑制时，肿瘤发病率增高，而在肿瘤进行性生长时，患者的免疫功能进一步受到抑制。

The results showed that high-concentration salt solution restrained significantly sprout rates of these varieties.

结果表明：高浓度盐溶液显著抑制水稻种子的发芽率，但品种间有较大差异；筛选出苗期极端耐盐品种6份，其中1级1份，2级4份，3级1份；极端耐盐水稻品种苗高的增长受高浓度盐溶液抑制，但品种间差异不显著；而盐溶液对极端耐盐水稻品种出叶速率的影响因品种而异。

In vitro studies by Hinter showed that AK auto Ab could promote the phagocytosis of intermediate filament aggregates by human monocytes and polymorphonuclear neutrophils.

所取得的主要进展有：①证实AK 第四军医大学博士学位论文2auto Ah在正常人和多种动物体内广泛存在，明确其与皮肤多种生理和病理过程密切相关；②发现 AK auto Ah能够抑制培养角质形成细胞伙eratinoc刊e，KC）的增殖代谢，可以抑制KC产生兔疫介质如1＊－6、IL.8，促进＊C凋亡：首次提出＊K allt。

Human/rat homology collagen type I siRNA plasmid not only direct repress collagen type I gene expression in rat inesangial cells, but also have the same inhibition action of TGF-β1 induced overexpression of collagen type Ⅰ.

本实验构建的人鼠同源Ⅰ型胶原siRNA质粒，在大鼠系膜细胞内不仅能够直接抑制Ⅰ型胶原的基因表达，而且对TGF-β1诱导的I型胶原表达增加同样具有较好的抑制作用。

Administration of 2.5-40μmol/L PDTC for 24-72 hours could significantly inhibit HPF proliferation in a dose-and time- dependent manner. CONCLUSION:The inhibition effect of PDTC on HPFs is significantly, which is dose- and time-dependent.

PDTC对体外培养的HPF细胞有抑制作用，在一定浓度和时间范围内抑制作用呈剂量与时间依赖性。

Administration of 2.5-40μmol/L PDTC for 24-72 hours could significantly inhibit HPF proliferation in a dose-and time- dependent manner. CONCLUSION:The inhibition effect of PDTC on HPFs is significantly, which is dose- and time-dependent.· KEYWORDS: PDTC; human pterygium fibroblast; prolifera- tion

PDTC对体外培养的HPF细胞有抑制作用，在一定浓度和时间范围内抑制作用呈剂量与时间依赖性。

HupA had only a weak inhibitory effect on the voltage-gated soldium channels at a concentration of 1 mM.

HupA对〓和〓的抑制作用与胆碱能系统无关，加入Atropine或Carbacol对HupA的抑制作用没有影响。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。