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By using microcalorimetric method, the thermogenesis power curves of aerobacter aerogenes growth at different temperature and under the action of different drugs were determined.

用微量热法研究了4种重金属离子对丝状真菌生长抑制的热功率输出曲线,得到了它在不同浓度重金属离子作用下的生长速率常数k、抑制率I、半抑制浓度IC50等参数,其抑制顺序为:Cd2+>Hg2+>Pb2+>Cu2+。

It is existed competitiveness inhibition of 6APA, non-competitiveness inhibition of PAA and substrate inhibition of Penicillin on the hydrolysis of benzylpenicillin to 6APA and PAA by an immobilized penicillin amidase. The heat conductive coefficients were determined on the vacuum elevation liquid membrane concentration. The thermodynamics and kinetics of PAA extraction were studied on the organic solvent extraction of the above solution.

研究证明固定化青霉素酰化酶裂解反应是典型的底物、产物抑制酶反应,其反应动力学数据表明,青霉素、苯乙酸以及6APA对反应分别存在底物抑制、非竞争性抑制和竞争性抑制;真空升膜浓缩适应热敏性以及粘度不大的物系,对于6APA水溶液的真空升膜浓缩过程研究得到了浓缩实验的传热系数;浓缩液萃取主要是提取出其中的苯乙酸,本文测定了不同温度以及溶剂条件下的苯乙酸溶解度,并观测了苯乙酸萃取动力学。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PHφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。

FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PMφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。

The results of bioassay experiments with 10 commonly used fungi showed that, all the title compounds had satisfactory fungicidal activity against Botrytis cinerea, the growth inhibition rate of compounds 5ae, 5ag, 5bd against Botrytis cinerea were up to 70% and for 5ad, 5cd, 5ce were more than 60%; compound 5bd exhibited fungicidal activity against Pellicularia sasakii with growth inhibition up to 60%, the growth inhibition rate of compound 5cg against Colletotrichum lagenarium was 69%.

抑菌活性生物测定结果表明,合成的大部分化合物对黄瓜灰霉病菌均有较好的生长抑制作用,其中,化合物5ae、5ag和5bd的抑制率达到70%;化合物5ad、5cd、5ce的抑制率大于60%;5bd对水稻纹枯病菌抑制率大于60%,化合物5cg对西瓜炭疽病菌的抑制率为69%。

This conclusion is based on three groups of experiments with detached root tips of wheat seedlings: By following the time course changes of NO synthase , superoxide synthase and ABA accumulation under dehydration stress, we found that ABA accumulation was preceeded by the changes of NOS and superoxide synthase. ABA accumulation induced by dehydtrion stress and osmotic stress can be blocked by NO scanvegers and NOS inhibitors, while only dehydration stress-induced ABA accumulation can be blocked by ROS scanvegers. Exogenous applied NO or ROS induced ABA accumulation in root tips of wheat seedlings, and synergistic effects were found between NO and NO. The in planta expereiments also proved that ROS and NO are involved in water stress-induced ABA accumulation.Ⅱ.

证据主要来自以离体根尖为材料的实验:(1)通过检测干旱胁迫下小麦根尖NOS活性、O〓合成酶活性和ABA积累的时间变化进程,发现ABA积累滞后于ROS和NO的变化;(2)抑制剂实验表明,NO清除剂和NOS抑制剂可以抑制自然干旱胁迫及渗透胁迫诱导的小麦根尖ABA积累,ROS清除剂抑制自然干旱胁迫诱导的ABA积累而不抑制渗透胁迫诱导的小麦根尖ABA积累;(3)在非胁迫条件下施加外源的ROS或NO可以诱导小麦根尖积累ABA,ROS和NO之间具有协同作用。

It is possible that morphine applied to VLO depresses the GABAergic interneuronal activities that tonically inhibits the VLO output neurons projecting to PAG, leading to activation of the PAG-brainstem descending inhibitory system which depresses the nociceptive inputs at the spinal cord level.

可能是:吗啡供给到VLO通过抑制GABA能中间神经元对VLO-PAG投射神经元的抑制作用,这种去抑制效应,可能加强脑干下行抑制系统的活动,在脊髓水平抑制伤害感受性输入。

At different time point after exposure to ionizing radiation or ultraviolet of cells, apoptosis was detected by Hoechst 33342 staining and DNA fragmentation analysis, live cells were numerated by Tanpan Blue staining.

笔者首次研究了LRP16基因表达被抑制的MCF7和HeLa肿瘤细胞系对电离辐射及紫外照射的敏感性变化,发现抑制LRP16基因表达增加了肿瘤细胞的辐射敏感性。1材料和方法1.1LRP16基因表达被稳定抑制的细胞系建立采用内源性LRP16基因表达被稳定抑制的MCF7和HeLa细胞,其中M pl374及H pl374细胞抑制率为90%,M pl668

Results showed that the activity of soil poly-phenol oxidases and acid phosphatase, and soil respiration were suppressed by Starane at 0.5 and 5 mgkg^(-1) dry soil, respectively, during the first several days of experiment, but were slight promoted thereafter. In contrast, treatment with Starane at 50 mgkg^(-1) stimulated at the beginning of experiment but inhibited following that time the activity of soil poly-phenol oxidases and acid phosphatase and soil respiration. Activity of urease was stimulated at the beginning but inhibited in the following days by Starane at 0.5 and 50 mgkg^(-1) dry soil, respectively. However, the pattern of stimulation of urease activity at first several days of experiment followed by reduction to the basil level was observed. With respect to invertase, its activity was constantly depressed in the presence of Starane.

结果表明使它隆在0.5mgkg^(-1)和5mgkg^(-1)质量分数时对土壤多酚氧化酶、酸性磷酸酶和呼吸强度的影响为轻微抑制-激活-恢复稳定的趋势,50mgkg^(-1)质量分数时为轻微激活-抑制-恢复稳定的趋势;使它隆在0.5mgkg^(-1)和50mgkg^(-1)质量分数时对土壤脲酶活性的影响为激活-恢复稳定的趋势,5mgkg^(-1)时则处于抑制-激活的趋势;各质量分数的使它隆浓度对土壤蔗糖酶和土壤全酚均为抑制作用,且质量分数越大抑制越强烈。

The depressing ability of the macromolecule organic depressants can be improved by the increase of their D.S.. The high D.S. CPVA and CPEG show strong depressing ability to calcite, while CPEG indicates strong depressing ability to diaspore, and HPAM to pyrite.The depressing mechanism of organic depressants was confirmed by the measurements of zeta potential, contact angles, adsorption capacity and IR spectrum.

利用动电位、接触角、吸附量和红外光谱等测试方法和手段,探讨了抑制剂的作用机理:苯氧乙酸类小分子抑制剂与方解石之间可发生较强的化学作用,可以选择性地吸附在方解石表面,使捕收剂发生解吸或阻止捕收剂在矿物表面的吸附而使矿物受到抑制;大分子抑制剂则主要是依靠亲固基吸附在矿物表面,再利用其长链的强亲水性而使矿物受到抑制。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。