抑制...

And the different concentrations of natural monoclonal anti-keratin antibody IgM 3B4 were incubated with the mixed suspenions of Candida albicans yeast phase with malpighian cells, human buccal epithelial cells, endothelial cells of fetal umbilical vein, respectively, to observe the action of natural monoclonal anti-keratin antibody IgM 3B4 to the adhesion of Candida albicans to malpighian cells, human buccal epithelial cells and endothelial cells of fetal umbilical vein.

结果：与对照组比较，不同浓度的单克隆天然抗角蛋白抗体IgM3B4均能抑制白念珠菌芽管生成，并且抗体浓度越高，抑制白念珠菌芽管形成的作用越明显；同时单克隆天然抗角蛋白抗体IgM3B4能够显著减少白念珠菌与角质形成细胞、上皮细胞、内皮细胞的粘附，其抑制作用与单克隆天然抗角蛋白抗体IgM3B4的浓度呈正相关。

Keratin antibody IgM 3B4 to the adhesion of Candida albicans to malpighian cells, human buccal epithelial cells and endothelial cells of fetal umbilical vein. RESULTS: It was found that the different concentrations of natural monoclonal anti??keratin antibody IgM 3B4 could inhibit Candida albicans germ tube formation and adhesion of Candida albicans to malpighian cells, human buccal epithelial cells and endothelial cells of fetal umbilical vein.Its inhibitory action was positively related to the level of natural monoclonal anti??

结果：与对照组比较，不同浓度的单克隆天然抗角蛋白抗体IgM 3B4均能抑制白念珠菌芽管生成，并且抗体浓度越高，抑制白念珠菌芽管形成的作用越明显；同时单克隆天然抗角蛋白抗体IgM 3B4能够显著减少白念珠菌与角质形成细胞、上皮细胞、内皮细胞的粘附，其抑制作用与单克隆天然抗角蛋白抗体IgM 3B4的浓度呈正相关。

With it, simple, mechanistically significant and highly predictive QSAR models were developed. These QSARs successfully model and predict the short-term phytotoxicity of substituted phenols involved both polar narcosis and bio-reactivity, the growth inhibition toxicity to Saccharomyces cerevisiae of substituted nitrobenzenes with mixed mechanisms of toxic action based on electrophilicity and the growth inhibition toxicity to Saccharomyces cerevisiae of large set of substituted benzenes with complex molecular structures and multiple mechanisms of action.

应用响应曲面分析方法建立了形式简单、意义明确并且具有高度预测性的QSAR模型，成功地预测了具有多种毒性机制的取代苯酚对高等植物的短期生长抑制毒性、具有多种亲电反应性机制的取代硝基苯对酿酒酵母菌生长抑制的反应性毒性以及结构复杂、机制多样的78种取代苯衍生物对酿酒酵母菌生长抑制毒性。

Results: At the concentrations of 0.1, 1 and 10 μmol/L, berberine dose-dependently suppressed the formation of TRAP-positive multinucleated cells, the TRAP activity and the osteoclastic bone resorption. The strongest inhibitory effect was exhibited at the concentration of 10 μmol/L, with the inhibiting rate of 60.45%, 42.12% and 72.69% respectively.

结果：小檗碱在0.1~10μmol/L范围内，浓度依赖性地抑制TRAP阳性多核破骨细胞的形成和TRAP活性，减少破骨性骨吸收陷窝的面积；在10μmol/L浓度下，对破骨细胞的抑制作用最强，对TRAP阳性多核破骨细胞的形成和TRAP活性的抑制率分别达到了60.45%和42.12%，骨吸收陷窝面积减少72.69%。

Results: Proliferation of K562 cells was significantly inhibited by naringenin and the IC50 at 24, 48 and 72h were 455, 225 and 175μmol/L respectively. Cell growth inhibition and apoptosis were observed under light microscope and transmission electron microscope. Observation by flow cytometry indicated that K562 cells were blocked in G0/G1 phase of cell cycle in naringenin group, and S phase cells were remarkably decreased. PCNA expression in each treatment group was remarkably less than in control group.

结果：柚皮素对K562细胞增殖有明显抑制作用，作用24，48和72h后的半数抑制浓度(IC50)分别为455，225和175μmol/I；柚皮素处理组细胞在普通光镜和电镜下均见观察到显著的增殖抑制和典型的细胞凋亡形态学改变；流式细胞仪分析证实柚皮素能使K562细胞聚积在G0/Gl期，S期细胞减少；在处理组PCNA的表达显著低于对照组。

Usually, anti-apoptotic protein is insulated in organella, restraining the release of pro-apoptotic factor and controlling cell apoptosis. however, interacting with pro-apoptotic protein, it can not restrain apoptosis, induce the loss of mitochondrial function, accelerate the release of pro-apoptotic factor and result in apoptosis.

抑凋亡蛋白平时被隔离在线粒体等细胞器内抑制促凋亡因子的释放，具有抑制细胞凋亡的功能，但一旦与激活的促凋亡蛋白发生相互作用后，便丧失了对细胞凋亡的抑制作用，造成线粒体等细胞器的功能丧失和细胞器内促凋亡因子的释放，导致细胞凋亡。

Anti-apoptotic and pro-apoptotic factors have synergistic effect and play a switch role. Usually, anti-apoptotic protein is insulated in organella, restraining the release of pro-apoptotic factor and controlling cell apoptosis.

抑凋亡蛋白平时被隔离在线粒体等细胞器内抑制促凋亡因子的释放，具有抑制细胞凋亡的功能，但一旦与激活的促凋亡蛋白发生相互作用后，便丧失了对细胞凋亡的抑制作用，造成线粒体等细胞器的功能丧失和细胞器内促凋亡因子的释放，导致细胞凋亡。

These changes were prevented by genistein (a protein tyrosine kinase inhibitor) and antioxidant N-acetyl-L-cysteine, but promoted by sodium orthovanadate (a protein phosphatase inhibitor), which were administered to the SD rats 20 min before ischemia.

进一步的研究表明，缺血前20 min腹腔注射给药，然后缺血30 min，发现蛋白酪氨酸激酶抑制剂染料木黄酮和抗氧化剂N-乙酰半胱氨酸能显著地抑制核内STAT3的磷酸化水平及DNA结合活性的增加(磷酸化水平从2.3和2.5倍分别降为1.2和1.4倍， DNA结合活性则从2.8和3.7倍分别降为1.1和1.5倍)，而蛋白酪氨酸磷酸酶抑制剂矾酸钠则能明显地促进他们的增高(磷酸化水平从2.0倍增到3.4倍， DNA结合活性从3.1倍增为5.1倍)。

Zn-La alloys increase the overpotential ofhydrogen evolution, Tafel slope 〓 and polarization, decrease the corrosion current density, inhibitthe corrosion of zinc electrode in alkaline solution, decrease anode Tafel slope 〓, promotedischarge reaction of zinc electrode, have higher passivation current density, inhibit thepassivation of zinc electrode, avoid the oversaturation of zincate in electrolyte, greatly increase〓 diffusion coefficient, decrease Tafel slope 〓, polarization and the overpotential of deposition,inhibit the dendrites formation and improve the electrodepostion of Zn.

实验结果表明，Zn-La合金电极显著改善了锌电极的各项电化学性能：提高析氢过电位、析氢过程Tafel斜率〓和极化，减小腐蚀电流密度，抑制锌电极在碱液中的腐蚀；降低阳极Tafel斜率〓，促进了锌电极的放电反应；具有较高的维钝电流密度，抑制锌电极的钝化；有效避免了溶液中锌酸盐的过饱和现象：使〓的扩散系数明显增大：降低Zn沉积过程的Tafel斜率〓、极化和沉积过电位，明显抑制锌枝晶的生长，改善了锌的电沉积性能。

Phenylmethylsulfonyl fluoride (174.2 mg/mL), chicken ovomucoid (1000 mg/mL) and soy-bean trypsin inhibitor (1000 mg/mL) could inhibit enzyme activity, which indicated that the enzyme belonged to serine protease group. On plasminogen-free fibrin plates and plasminogen fibrin plates, the fibrinolytic activity had no obvious difference, indicating that the enzyme was a fibrinolytic enzyme which degraded fibrin directly, but not a plasminogen activator which degraded fibrin by activating plasminogen.

此菌株产生的纤溶酶在50℃以下和pH5.0~11.0范围内具有较好的稳定性，最适作用温度为42℃；最适pH值为9.0；Mg2+、Ca2+对此酶有明显的激活作用，而Cu2+能完全抑制酶的活性；174.2 mg/mL的苯甲基磺酰氟、1000 mg/mL的鸡卵类粘蛋白和1000 mg/mL大豆胰蛋白酶抑制剂能完全抑制酶活性，初步说明此酶属于丝氨酸蛋白酶类；体外溶纤作用表明，该酶溶解纤维蛋白的方式是直接溶解，而不是通过激活纤溶酶原。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。