抑制...

Both CaCN2 and urea inhibited the chlamydospore germination, mycelial growth and sporulation of the pathogen, but CaCN2 by using at the rates of 0.5 and 1.0%, had two inhibition zones for chlamydospore germination with time while urea had only one. Calcium cyanamide was also more effective on reducing mycelial growth and sporulation of the pathogen than urea did. Therefore, the suppression of pea wilt might be due to fungicidal effect of the intermediate products including hydrogen cyanamide and urea from calcium cyanamide.

由氰氮化钙（0.5及1.0%处理者）之抑制曲线在不同的时间出现两个抑制区，而尿素则仅有一个，及氰氮化钙对萎凋病菌菌丝生长及产胞的影响远较尿素为甚，显示氰氮化钙之所以能有效抑制萎凋病的主要因子，或许是来自其中间产物，包括尿素及氟酸的杀菌作用。

The inhibiting influenza A virus effect of catechu extract was observed by means of chick-embryo culture , and the inhibitory activity of catechu extract on influenza A virus in vitro was observed by the hemagglutination inhibition test.

用狗肾传代MDCK细胞培养法观察儿茶提取物抑制甲型流感病毒的致细胞病变作用；用鸡胚培养法观察儿茶提取物抑制甲型流感病毒增生的作用；用红细胞凝集试验观察儿茶提取物体外直接抑制甲型流感病毒的作用。

The new model targeted on Cathepsin K was proved to be feasible and effective in the screening for antiosteoporosis drug.

初筛以抑制木瓜蛋白酶的活性为指标，经筛选从1000株真菌中得到9株具有较强抑制效应的真菌，复筛采用对纯化的组织蛋白酶K的特异性抑制效应为指标。

The columna soil study showed that strain NBT had the ablity of potassiumuptake ,making losed potassium from the soil inoculated with the bacterium wasdecreased by

通过土柱试验发现，硅酸盐细菌NBT菌株还具有保钾功能，供试土壤接菌处理后的土壤滤液中流失的钾比对照减少35.5-56.5％，经方差分析，差异达显著水平；另外，硅酸盐细菌NBT菌株与农药的相容性试验表明，无论在大田农药施用浓度和残留浓度内的丁草胺、绿黄隆、三唑酮粉、多菌灵、马拉硫磷等农药对NBT菌株没有抑制作用；乐果、甲基1605在大田施用浓度下，对NBT菌株有一定抑制作用，而在残留浓度下，对NBT菌株无明显抑制作用。

The expression level of metabolitic enzyme (CYP1A1, CYP1B1) and its correlation with cell differentiation /apoptosis were studied as well. The influence of resveratrol in cell cycle was determined with FCM. Results 1 Resveratrol not only suppresses the growth of medulloblastoma cells in a dose and time related fashion but also induces cell differentiation and apoptosis. Resveratrol promotes differention of UW228-1,-2 cells to forward glia, UW228-3 and Med-3 cells to neuron. A treatment of resveratrol in the concentration of 100μM for 48hrs comit most of cells die of apoptosis. 2 Among the four cell lines Fas and Caspase-3 were constantly expessed, whereas FasL was absent irrespective to the drug treatment. 3 ICC, RT-PCR, Western-blot hybridization and EROD enzymatic activity assay demonstrated that expression of CYP1A1 is different after treatment with resveratrol in four cell lines, up-regulated in three UW228 cell lines in a dose dependent manner but down-regulated in Med-3 cells. Suppressive effect of resveratrol on CYP1B1 expression is the same among four medulloblatoma cell lines. 4 Cell cycle distribution of UW228-3 was greatly changed after treatment.

结果：1、白藜芦醇以时间和剂量依赖性方式抑制髓母细胞瘤细胞生长，同时促进细胞的分化和凋亡：白藜芦醇促使UW228-1、-2靶细胞向神经胶质细胞方向成熟分化，UW228-3、Med-3细胞向神经元细胞方向成熟分化，以100μM作用48小时效果显著；2、四个细胞系均有Fas和Caspase-3表达，但无Fas-L基因表达和蛋白活性产生，因此难以形成Fas相关性死亡通路；3、白藜芦醇处理前后CYP1A1基因的表达在各细胞系略有不同：UW228-1，-2，-3三个细胞系白藜芦醇以剂量相关性方式上调CYP1A1的表达，而Med-3细胞系，白藜芦醇却抑制CYP1A1的表达；四个细胞系在白藜芦醇处理后CYP1B1的表达均受到抑制；4、UW228-3细胞系经白藜芦醇作用后细胞周期有较大改变，表现在G0/G1期在整个细胞周期中所占的比例增加，而其它时期则相应减少。

Methods Mimicry and speculation on possible displaced amino acids in proper positions of peptide increased the biological effects of TNFR blocking peptide by compote modeling. The original peptide and its mutant were synthesized. The competitively inhibitory effects on green fluorescence protein-tumor necrosis factor fusion protein with TNFR were compared between original peptide and its mutant (receptor competitively inhibitory binding assays). The inhibitory effects on cytotoxicity were compared between original peptide and its mutant.

通过计算机模建，模拟并推测提高TNFR封闭肽生物学效应需置换的位点和氨基酸；合成原封闭肽和突变肽；受体竞争抑制结合实验比较原肽与突变肽对绿色荧光蛋白－肿瘤坏死因子融合蛋白结合TNFR的竞争抑制效应；细胞毒作用抑制实验比较原肽与突变肽对TNFR的封闭效应。

RESULTS:（1）Three KDR-siRNA expression vectors were digested by Nde Ⅰ and Sma Ⅰ and produced two fragments of 713 bp, 5 480 bp and 2 403 bp, 3 790 bp, respectively, which were congruous with expectation.

KDR-小干扰RNA对A549细胞中KDRmRNA水平的影响：与阳性对照组、阴性对照组、空白对照组和正常对照组的A549细胞相比，KDR-siRNA1，2，3表达载体转染后的A549细胞KDR基因表达水平均明显受到抑制，抑制率分别为64%、81%和72%，其中以KDR-siRNA2抑制作用最为明显。

In contrast, in second and fourth experiments, decision latencies also showed both semantic and syntactic effects, but latencies appeared to be conjointly determined by syntactic and semantic context.

实验一和实验三发现，语义违反对词汇命名没有抑制作用，而句法违反对词汇命名有抑制作用。实验二和实验四发现，语义违反和句法违反均对词汇决定任务有抑制作用。

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

In this method, we use the pooled correlogram based on human auditory model to extract the pitch of speech. An unsupervised lateral inhibitory network is used to get the peak position, which simulates the lateral inhibitory phenomenon in human auditory system.

采用基于人耳听觉模型的相关图来提取语音信号的基频，运用无监督的侧抑制神经网络来模拟人耳侧抑制属性进行基频检测，为了克服在低信噪比情况下侧抑制神经网络的误判问题，引入了相邻语音帧的语音基频的帧间约束。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。