托特尔

Allison Abbate, Colleen Atwood, John August, Rick Baker, Helena Bonham Carter, Felicity Dahl, Johnny Depp, Danny Devito, Danny Elfman, Carlos Grangel, Ray Harryhausen, Martin Landau, Rick Heinrichs, Christopher Lee, Lindsay Macgowan, Shane Mahan, Ian Mackinnon, Alex Mcdowell, Victoria Price, Ken Ralston, Paul Reubens, Deep Roy, Winona Ryder, and Richard Zanuck.

阿利森阿巴特，科琳阿特伍德，约翰奥古斯特，瑞科贝克，海伦娜邦汉卡特，富临达尔，约翰尼德普，丹尼德维托，丹尼叶夫曼，卡洛斯Grangel，雷·哈里豪森，马丁兰道，里克海因里希斯，克里斯托弗李，林赛麦高恩，巴蒂尔马汉，伊恩麦金农，亚历克斯道尔，维多利亚价格，拉尔斯顿，保罗鲁宾斯，深罗伊，薇诺娜瑞德，和理查德扎纳克。

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

The South West is a region of contrasts对比,对照,(对照中的差异-- Wiltshire, where South West England begins less than an hour from London; Gloucestershire, home to the Forest of Dean and the Cotswolds; Dorset, an area of outstanding natural beauty and bordered by the Jurassic coastline; Bristol and Bath, with centuries of history and culture; Somerset, a mix of heather covered Exmoor and the levels of Devon, with two coastlines and wide open spaces; Cornwall, bounded by the sea and steeped in Celtic tradition with the delightful Scilly Isles, each with its own features and attractions.

西南部的景色对比鲜明威尔特郡是西南部的开端，离伦敦不到一小时路程；格洛斯特郡拥有迪恩森林和科茨沃尔德丘陵；多塞特郡是杰出自然风景区，与侏罗纪海岸线接壤；布里斯托尔和巴斯享有几个世纪的历史与文化；萨默塞特郡有石楠覆盖的埃克斯穆尔和层层叠叠的塞奇穆尔高沼；德文郡的两条海岸线和广阔空间相互衬托；康沃尔郡以海为界，凯尔特传统根深蒂固，锡利群岛美丽如画；每个郡都各有特色。

Cast ::, Gene Hackman as Henry Hearst, Morgan Freeman as Captain Victor Benezet, Thomas Jane as Detective Felix Owens, Monica Bellucci as Chantal Hearst, Nydia Caro as Isabella, Miguel ngel Suárez as Superintendent ..

演员：：，金哈克曼亨利赫斯特，摩根弗里曼船长维克托贝尼泽特，托马斯简费利克斯欧文斯作为侦探，莫妮卡贝鲁奇作为尚塔尔赫斯特，尼迪亚卡罗为伊莎贝拉，米格尔安赫尔苏亚雷斯院长。。。

Midfielders: Osvaldo Ardiles Ademir Didi Roberto Rivelino Gerson Falcao Clodoaldo Zico Enzo Francescoli Paul Gascoigne Michel Platini Lothar Matthaus (W Germany/Germany) Wolfgang Overath Bobby Charlton Johan Neeskens Frank Rijkaard Ruud Gullit Johnny Rep Rene van der Kerkhof Wim Van Hanegem Grzegorz Lato Gheorghe Hagi Enzo Scifo Dragan Dzajic Nils Liedholm Teofilo Cubillas Michael Laudrup Josef Masopust Carlos Valderrama Junich Inamoto.

中场：阿迪莱斯，阿德米尔、迪迪、利维里尼、贾尔森、法尔考、克罗多亚尔队储济科，弗朗西斯科利，加斯科茵、博比·查尔顿，普拉蒂尼，马特乌斯、奥弗拉特，内斯肯斯、里杰卡尔德、古力特、约翰尼·雷普、范德科克霍夫、范哈内亨，拉托，哈吉，希福，德拉甘·德扎季奇，利德霍尔姆，库比拉斯，迈克尔·劳德鲁普，，巴尔德拉马，稻本润一日本

Midfielders: Osvaldo Ardiles, Ademir, Didi, Roberto Rivelino, Gerson, Falcao, Clodoaldo, Zico, Enzo Francescoli, Paul Gascoigne, Michel Platini, Lothar Matthaus (W Germany/Germany), Wolfgang Overath, Bobby Charlton, Johan Neeskens, Frank Rijkaard, Ruud Gullit, Johnny Rep, Rene van der Kerkhof, Wim Van Hanegem, Grzegorz Lato, Gheorghe Hagi, Enzo Scifo, Dragan Dzajic, Nils Liedholm, Teofilo Cubillas, Michael Laudrup, Josef Masopust, Carlos Valderrama, Junich Inamoto.

中场：阿迪莱斯，阿德米尔、迪迪、利维里尼、贾尔森、法尔考、克罗多亚尔多、济科，弗朗西斯科利，加斯科因、博比·查尔顿，普拉蒂尼，马特乌斯、奥弗拉特，内斯肯斯、里杰卡尔德、古力特、约翰尼·雷普、范德科克霍夫、范哈内亨，拉托，哈吉，希福，德拉甘·德扎季奇，利德霍尔姆，库比拉斯，迈克尔·劳德鲁普，，巴尔德拉马，稻本润一日本

Chelsea inquired about the 25-year-old earlier this year and Benitez believes the London club are now ready to offer as much as ?0m. Fearing that Liverpool's hard-up owners Tom Hicks and George Gillett, might struggle to resist, Benitez has made inquiries about Almeira centre-forward Alvaro Negredo as a replacement. Negredo is half-owned by Madrid and available for ?5m,' the newspaper reports.

年初切尔西询价25岁的托雷斯，贝尼特斯认为切尔西可能会提出更高的7000万的报价，而手头正缺钱的美国老板希尔斯和吉列可能会就此松口，贝尼特斯已经寻找内格雷多作为托雷斯的替代品，内格雷多一半所有权属于皇马，据报道他的身价是750万。

Know that, having regard to God and for the salvation of our soul, and those of all our ancestors and heirs, and unto the honour of God and the advancement of the holy Church, and for the reform of our realm, by advice of our venerable fathers, Stephen archbishop of Canterbury, primate of all England and cardinal of the holy Roman church, Henry archbishop of Dublin, William of London, Peter of Winchester, Jocelyn of Bath and Glastonbury, Hugh of Lincoln, Walter of Worcester, William of Coventry, Benedict of Rochester, bishops; of master Pandulf, subdeacon and member of the household of our lord the Pope, of brother Aymeric (master of the Knights of the Temple in England), and of the illustrious men William Marshall earl of Pembroke, William earl of Salisbury, William earl of Warenne, William earl of Arundel, Alan of Galloway, Waren Fitz Gerald, Peter Fits Herbert, Hubert de Burgh, Hugh de Neville, Matthew Fitz Herbert, Thomas Basset, Alan Basset, Philip d'Aubigny, Robert of Roppesley, John Marshall, John Fitz Hugh, and of other faithful subjects.

知道这一点，考虑到上帝拯救我们的灵魂，和所有我们的祖先和继承人，和你们的荣誉上帝和提高罗马教会，并为我们的改革领域，我们的意见尊敬的父亲，斯蒂芬坎特伯雷大主教，灵长类动物的所有英格兰和红衣主教的罗马教会，亨利都柏林大主教威廉的伦敦，彼得温切斯特，乔斯林巴斯和格拉斯顿伯里，休林肯，沃尔特伍斯特，威廉考文垂笃罗彻斯特主教；主Pandulf ， subdeacon和家庭成员我们的主教宗的弟弟艾默里克（船长圣堂骑士团在英格兰），和杰出的男子威廉彭布罗克伯爵马绍尔群岛，威廉索尔兹伯里伯爵，威廉伯爵Warenne ，威廉伯爵阿伦德尔艾伦加洛威，瓦伦菲茨杰拉尔德，彼得适用赫伯特，贝尔德1646 ，内维尔休日，马修费赫伯特，托马斯巴萨特艾伦巴萨特，菲利浦德欧比尼，罗伯特的Roppesley ，约翰马歇尔，约翰费休，以及其他忠实科目。

Know that, having regard to God and for the salvation of our soul, and those of all our ancestors and heirs, and unto the honor of God and the advancement of his holy Church and for the rectifying of our realm, we have granted as underwritten by advice of our venerable fathers, Stephen, archbishop of Canterbury, primate of all England and cardinal of the holy Roman Church, Henry, archbishop of Dublin, William of London, Peter of Winchester, Jocelyn of Bath and Glastonbury, Hugh of Lincoln, Walter of Worcester, William of Coventry, Benedict of Rochester, bishops; of Master Pandulf, subdeacon and member of the household of our lord the Pope, of brother Aymeric (master of the Knights of the Temple in England), and of the illustrious men William Marshal, earl of Pembroke, William, earl of Salisbury, William, earl of Warenne, William, earl of Arundel, Alan of Galloway, Waren Fitz Gerold, Peter Fitz Herbert, Hubert De Burgh, Hugh de Neville, Matthew Fitz Herbert, Thomas Basset, Alan Basset, Philip d'Aubigny, Robert of Roppesley, John Marshal, John Fitz Hugh, and others, our liegemen.

鉴于遵奉神意，为我辈及所有先祖后人之灵魂得救，为了神的荣耀和神的圣教会之精进，并为王国振兴计，在诸位尊敬的神父：坎特伯雷大主教兼全英格兰教长及圣罗马教廷红衣主教斯蒂芬、都伯林大主教亨利、伦敦主教威廉、温切斯特主教彼得、巴斯和格拉斯顿伯里主教乔切林、林肯主教休、沃切斯特主教沃尔特、考文垂主教威廉、罗切斯特主教本笃，副助祭兼我主教皇内府成员潘道夫，亚美迪克弟兄，以及各位杰出的贵族：彭布鲁克伯爵威廉·马歇尔、索尔兹伯里伯爵威廉、沃伦伯爵威廉、阿朗德尔伯爵威廉、加洛维的阿兰、沃伦·菲兹·杰罗德、彼得·菲茨·赫伯特、休伯特·德·伯、休·德·内维尔、马修·菲茨·赫伯特、托马斯·巴塞特、阿兰·巴塞特、菲利·德阿比尼、罗普斯雷的罗伯特、约翰·马歇尔、约翰·菲兹·休以及其他臣民们的谏议下，兹同意并签署条款如下

With the total number of works published amounting to almost 190 million, Diogenes has so far released more than 5,800 titles, out of which more than 2,000 are still available. These include classics such as Montaigne, Shakespeare, Moliere, Flaubert, Stendhal, Balzac, Dickens, Tolstoy, Chekhov; modern classics such as Georges Simenon, William Faulkner, F. Scott Fitzgerald, George Orwell, Carson McCullers, Patricia Highsmith; bestselling authors such as John Irving, Paulo Coelho, Donna Leon; and equally successful German-speaking writers such as Alfred Andersch, Friedrich D rrenmatt, Urs Widmer, Hugo Loetscher, Ingrid Noll, Jakob Arjouni, Erich Hackl, Bernhard Schlink, Doris D rrie, Martin Suter and Patrick S skind.

他们的作者名单包括了经典作家蒙田、莎士比亚、莫里哀、福楼拜、司汤达、巴尔扎克、狄更斯、托尔斯泰、契诃夫，现代经典作家乔治·西默农、威廉·福克纳、司各特·菲茨杰拉德、乔治·奥威尔、卡森·麦卡勒斯，派翠西亚·海史密斯，畅销书作家约翰·欧文、保罗·科埃略、唐娜·莱昂，还有同样出色的德语作家们，如艾尔弗雷德·安德森、弗里德里克·迪伦马特、乌尔斯·维特默尔，胡戈·罗彻尔，英格丽特·诺尔，雅各布·阿约尼，埃里希·海克尔，本哈德·施林克，桃丽丝·多利，马丁·苏特和帕特里克·聚斯金德。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。