托托

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

By that time, my mother, who was the oldest child, had already lost her 4-year-old son, Victor, when he died from the flu — a victim of poor medical care in their tiny Czechoslovak village.

在那个时候，我的母亲也失去了她4岁的儿子，维克托（由于他们所在的捷克斯洛伐克小村庄缺乏良好的医疗服务，维克托死于流感）。

Among his contributions the most significant is to justify the theorem of the impossibility of the Paretian liberal that there is no a social decision function that meets unrestricted domain, Paretian principle and minimal liberty simultaneously, which helped him win the Nobel Prize on economics.

而他影响最大的贡献是证明了帕累托自由的不可能，后者为他赢得诺贝尔经济学奖奠定了基础，其基本含义指不存在一种可以同时满足无限制域、帕累托原则和最低限度的自由这三个条件的社会决策函数。

In this paper another deductive proof of the algorithms for the recursive solution of the system of linear equations with a Toeplitz coefficient matrix is considered, and formulas for the specific recursive solution of the various forms of the system of linear equations in accordance with a Toeplitz coefficient matrix are given.

本文给出了具有托布里兹系数矩阵线性方程组递推解法算式的另一推导证明方法，并给出了基于托布里兹系数矩阵的各种线性方程组的具体递推解法公式。

Mr Cameron's demagogic remarks about burglars hinted at the anxiety. They also point to a fundamental problem with the Tory prospectus.

卡梅隆就窃贼问题煽动性的演说已在暗示托利党的不安了，不仅如此，演说还指到了托利党政策的一个基本问题。

Hongkong Runming everyday products Co.,Ltd. is a manufacturer of kitchen bothroom widget and ornaments such as towel support,glass support,cup support, soap support,toilet paper box,deodorize sink etc.Xinxing Frame Manufacturing Co.,Ltd.

本公司是一家专业生产厨房、卫浴间挂件和装饰件的厂家，专门从事厨房、卫浴间各式毛巾托架、毛巾挂环、玻璃置物架、杯架、香皂托架、纸巾盒、防臭地漏等五金具的设计和制造，生产规模较大，产品种类繁多，形式多样。

Objective To observe the effect of serum kalium on depressurization of captopril combine with Indapamide and using them alone.

目的 观察卡托普利联合吲达帕胺与单用吲达帕胺、卡托普利降压疗效及对血钾的影响。

In this paper,the Raman spectrum were used to study sapphire,dichroite,aquamarinl,topaz and kyanite,it is found that the characteristic Raman translocations of sapphire which are caused by Al-O vibration are 413cm-1,640cm-1 and 668cm-1,the characteristic Raman translocations of dichroite which are caused by Si-O vibration are 550cm-1,662cm-1,964cm-1and 1176cm-1,the characteris.

本文通过对蓝宝石、堇青石、蓝色托帕石、海蓝宝石和蓝晶石的拉曼光谱进行测试与研究，得到蓝宝石具有由Al-O振动引起的特征拉曼位移413cm-1，640cm-1和668cm-1；堇青石具有由Si-O振动引起的特征拉曼位移550cm-1，662cm-1，964cm-1和1176cm-1；海蓝宝石具有由Si-O振动引起的特征拉曼位移678cm-1，1064cm-1，1232cm-1；蓝色托帕石具有由Si-O振动引起的特征拉曼位移844cm-1和924cm-1；蓝晶石具有由Si-O引起的特征拉曼位移933cm-1和1133cm-1。

Sargassum for dioecism, sexual maturity, from the use of reproductive care on the formation of reproductive Waterloo oocyst discharge hole, adhesion in the reproductive care around fertilization.

羊栖菜为雌雄异株，性成熟时，由生殖托上形成的生殖窝孔中排出卵囊，粘附于生殖托周围进行受精。

Distressingly, however, Tintoretto looks as if a tailor scissored out his head, had misgivings and quickly stitched it back.

可惜的是，丁托列托看起来像被裁缝剪开了脑袋，心惊胆颤之后又匆忙缝合起来。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。