成骨的

Kanzawa pointed, the abdominal vertebra BMD of PTH gene individuals in BB genetype is obviously higher than those of Bb and bb genetype,so he considered that the BstBI polymorphism of PTH gene has dependability with BMD while the DraⅡpolymorphism of PTH gene has no dependablity with BMD.3 The polymorphism of estrogen receptor gene and postmenopausal osteoporosisPMOP is a metabolic bone disease existing in post-menopause femmes, as a result of these femmes\' hypofunction of ovary,ESG level drawdown and the disequilibrium of bone couple procedure,the bone resorption of osteoclast exceeds the bone formation of osteoblastic,osteopenia and bone fragility accrescence have developed,then induces fracture and so on.

Kanzawa等研究发现，BB型PTH基因人的腰椎BMD较Bb、bb型显著为高，认为PTH基因BstBⅠ多态性与BMD有相关性；但PTH基因DraⅡ多态性则与BMD无相关性。三雌激素受体基因多态性与绝经后骨质疏松绝经后骨质疏松是指绝经后妇女由于体内卵巢功能低下，雌激素水平低落，骨偶联过程失衡，破骨细胞的骨吸收大于成骨细胞的骨形成作用所导致的骨量减少，骨脆性增加，进而易于发生骨折的代谢性骨疾病。

Experiments on decalcification and activation of osteoinductive ability, comparison between the osteogenesis of demineralized bone matrix in orthotopic and in heterotopic sites, and correlation between immune response to allograft of bone and osteoinductive activity of the graft, were reported in this paper. 1. Syngeneic deminerolized bone matrix and the mixture of DBM with bone ash or acid-soluble protein extracted from demineralization was implanted into muscle pouch of mice, subsequently, the inhibition of DBM osteoinduction by bone ash or acid-soluble protein was demonstrated with histological and by means of alkaline phosphatase assay.

本文对脱钙处理使骨诱导活性表达的作用、脱钙骨基质植入不同部位的成骨表现，以及同种异体骨移植引发的免疫反应与骨诱导活性的内在关系三方面进行了研究：（1）在小鼠肌肉植入同系脱钙骨基质及其与脱钙所去除的骨矿盐和酸溶性蛋白混合物，碱性磷酸酶和组织学检查表明：骨矿盐和酸溶性蛋白具有抑制脱钙骨基质骨诱导活性的作用。

Radiography and double fluorochrome labeling were taken. Dogs were sacrifice at 1, 3, 6 months post operation and image analysis were done on undemineralized slices then subject to statistical analysis by SAS software, Version 6. 21. 3. BMSCs in vitro induced and proliferated through complete blood culturing were seeded into tricalcium phosphate , fdDBM and 2 kinds of coralline hydroxyapatite with 200μm and 500μm porosity (C200 and C500) respectively.

将全血培养法体外诱导、扩增培养的BMSCs分别与三磷酸钙(tricalcium phosphate，TCP)、两种孔径的珊瑚羟磷灰石（200μm，500μm）以及制备的fdDBM复合，体外培养4～7日后，进行扫描电镜、组织学观察，并行裸鼠皮下回植，了解包括空白DBM材料在内的5组样本的异位成骨情况，经IMAGER-PRO PLUS软件进行图像分析，并进一步行统计分析。

Then fracture models were measured using the electrometric method after fixed in the different fixation postures.

在此模型的基础上将部分单元假设成肉芽组织的弹性模量、泊松比和剪切模量，同样运用Super-Sap计算程序运行生成骨折线为横型、桡斜型和尺斜型三种腕舟骨腰部骨折模型，然后在这三种骨折模型的基础上通过力的加载后模拟得到腕关节在不同固定体位下各种工况的模型，共144个工况模型。

BACKGROUND: Defatting is to reduce the special cell surface antigens by clearing fat and lipoprotein, so as to decrease immunological rejection, improve the biocompatibility of allograft bone, and increase osteogenic potential. However, the effect of defatting on biomechanical performance of bone remains controversial.

摘要背景：脱脂的目的在于通过清除脂肪和脂蛋白，减少特殊细胞表面抗原，以降低免疫排斥反应，改善异体骨的生物相容性，提高异体骨移植的成骨能力，但目前有关脱脂对骨生物力学性能的影响尚无统一观点。

Breast cancer commonly metastasizes to bones, producing both osteolytic and osteoblastic deposits. Different markers for quantitative determination of bone turnover have been developed to evaluate bone metastases of breast cancer. The urinary deoxypyridionline, a crosslink product of collagen molecules found in bone and excreted in urine during bone degradation, and bone specific alkaline phosphatase, an isoenzyme localized in the membrane of osteoblasts and released in circulation during bone formation, were recently described as a group of markers of bone turnover in metastatic cancer.

乳癌患者常见骨髓转移造成溶骨性及成骨性沈积物，而利用不同标记来定量骨质转换形态，可以评估乳癌骨骼转移的变化，而尿液中Deoxypyridinoline是骨质内胶原分子在骨骼破坏分解时至尿中的产物，骨特殊碱性磷酸酵素是一种同形酵素，位於成骨细胞的外膜且在骨骼形成时释放至血液中，利用此两种生化标记，可以来预测乳癌转移至骨骼的转换情形。

In the period of 8 to 16 weeks after operation,new bone was formed continuously, artificial bone gradually reconstructed to mature lamellar bone,bone trabeculae and medullary cavity,etc. Conclusion The preparation of CPC is simple.

结果 CPC植入后4周有新生软骨形成及未成熟的骨组织，可见大量的软骨细胞、成骨细胞、胶原组织及较多的小血管。8～16周新骨继续生成，人工骨逐渐改建为成熟的板层骨、骨小梁和髓腔结构。

Results There existed new cartilage and new immature bone tissue in the bone substitute in 4 weeks after operation, as well as mass of cartilageous cells,osteoblasts, collagen tissue and more small vessels were seen. In the period of 8 to 16 weeks after operation,new bone was formed continuously, artificial bone gradually reconstructed to mature lamellar bone,bone trabeculae and medullary cavity,etc.

结果 CPC植入后4周有新生软骨形成及未成熟的骨组织，可见大量的软骨细胞、成骨细胞、胶原组织及较多的小血管。8～16周新骨继续生成，人工骨逐渐改建为成熟的板层骨、骨小梁和髓腔结构。

Pull piece of ossification is two character that offer to cutting bring up the rear to still withhold periosteum, parenchyma and blood paragraph, pull Zhang Qi inflict through securing what go up at its the drawing of specific size or outspread force, make bone paragraph new spirit of the second birth inside clearance is lengthened or widen skeletal, add the surgical skill that bone measures.

梗概： 牵张成骨(D istraction osteogenesis，DO)是对切断后仍保留骨膜、软组织及血供的两个骨段，通过固定于其上的牵张器施以特定大小的牵引或扩张力，使骨段间隙内再生新骨延长或拓宽骨骼，增加骨量的外科技术。

In the whole life of human being, bone is always in the process of new-old alteration, which means osteoclast absorbing old sclerotin and osteoblast forming new sclerotin.

人的一生中骨骼一直处于新旧更替的过程中，即由破骨细胞吸收旧的骨质，成骨细胞形成新的骨质。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。