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The coral/col lagen/rhBMP-2 composite possesses a superior osteoinduction and will be a new type of bone substitute to be used in orthopedic and maxillofacial surgery.

珊瑚/胶原/rhBM P-2复合人工骨具有良好的异位诱导成骨活性,是一种较理想的骨移植替代材料。

Results In define induction envioroment, HPMSCS can diferentiate into lipoblast、after 2 weeks, the induced cells are full of lipid droplet;HPMSCS can differentiate into osteoblasts, after 4 weeks, we can see calcified tubercle in the cells, calcium in the calcified tubercle can be dyed black by Von Kossa and ALP dying is positive reaction above 95%.

结果 HPMSCS在培养基中持续培养后,在特定诱导环境下,成功使其向成脂肪细胞转化,培养2周时,可见融合成团的脂滴充满整个细胞;成功使其向成骨细胞转化,培养4周以上可见明显钙化结节,von Kossa染色可将骨结节中沉积的钙染成黑色,碱性磷酸酶染色呈强阳性反应达到95%以上。

Result: The Mixed group including morroniside,sweroside and loganin with different dose all significantly promoted pro.

结果:六味地黄丸主要血中移行成分莫诺苷、獐牙菜苷、马钱子苷的混合物各剂量组均明显表现出对大鼠成骨细胞的促增殖作用。

Result: The Mixed group including morroniside, sweroside and loganin with different dose all significantly promoted proliferation of rat osteoblast.

结果:六味地黄丸主要血中移行成分莫诺苷、獐牙菜苷、马钱子苷的混合物各剂量组均明显表现出对大鼠成骨细胞的促增殖作用。

Methods The CXB combining BM was implanted into the sacrospinalis muscle of rabbits, and CXB implanted alone was used as control. Eighteen Japanese rablits with longear were used. The size of CXB was 5 mm×5 mm×5 mm, and the implanted materials were taken out at 2、 4、 8、 12、 16 and 24 weeks after implantation.

将CXB与BM复合及单纯CXB植入兔的骶棘肌内,术后2、4、8、12、16及24周取出植入材料作组织学及组织化学检查,观察植入材料的成骨作用。

At 54 weeks, plentiful growing bone and bone marrowlike tissue fully filled in pores created by biodegradation of CPC/CS.

方法试验分CPC/CS及CPC两组,三点弯曲试验测试材料的强度和弹性模量;组织学观察材料植入兔股骨22及54周的成骨状况。

OBJECTIVE: To assess the value of mandibular distraction osteogenesis in treatment of OSAS in patients with congenital micrognathia and the effect of the surgery on the patients' respiratory functions.

目的:探讨和评价下颌骨牵引成骨技术在治疗小下颌畸形伴OSAS中的应用价值及对呼吸功能的改善作用。

Methods: The multinucleated osteoclasts were derived by 1,25-dihydroxyvitamin D3 and dexamethasone from bone marrow cells in the coculture system with primary osteoblastic cells.

采用原代培养的成骨细胞和骨髓单核细胞联合培养的方法,在1.25-2维生素D3和地塞米松作用下,使骨髓单核细胞分化形成破骨细胞。

This review focused on the biological significance of matrix metalloproteinases in its regulation when mesenchymal stem cells differentiate into myoblastic, osteoblastic, chondroblastic, neural, and apidoblastic lineages.

文章详细阐述了基质金属蛋白酶在间充质干细胞分化为成肌细胞、成骨细胞、破骨细胞、神经细胞、脂肪细胞过程中所起的重要生物学作用,并对基质金属蛋白酶在间充质干细胞分化中的调控作用进行分析。

ConclusionSensory nerval bundles and vascular bundles can effectively accelerate the ossification of tissue engineered bones.They can be used as a construction method for nervalization after tissue engineered bone.

结论感觉神经束和血管束具有明显的促组织工程骨成骨作用,可以作为组织工程骨神经化构建的一种方法。

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