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Background: Mesenchymal stem cells are multipotent and have the ability to differentiate into bone.

背景:间充质细胞有多种潜能,可以分化成骨

OBJECTIVE: To investigate the effects of p38MAPK on the proliferation, differentiation and apoptosis of murine osteoblasts.

目的:观察p38MAPK对新生大鼠成骨细胞增殖、分化和凋亡的影响。

2Its one of cytology mechanisms of Qiang-gu-bao decoction on preventing and curing diabetes osteoporosis were related with promoting for osteoblastic cell proliferation 、 differentition and mineralization of formation,moreover inhibiting nonenzymic glycation reaction and reducing the formation of AGEs on the early stage, inhibiting the secretion of osseous absorptive cytokine, Consequently, Qiang-gu-bao decoction could inhibited bone resorption and promote for bone formation as well as regulated the bone metabolization.

2强骨宝方直接提取液及糖尿病模型大鼠载药血清均能促进 OB 增殖、分化及矿化成骨作用,并抑制早期糖基化反应,减少 AGEs 的形成,抑制 OB 分泌骨吸收因子,从而达到抑制骨吸收、促进骨形成、调节骨代谢,这可能是强骨宝方防治糖尿病性骨质疏松的细胞学机制之一。

We investigated the c-fos protein expression in nucleolus after the shear stress applied and found c-fos protein expression.

还利用流动小室方法对在剪应力作用下细胞核内原癌基因c-fos蛋白的翻译水平的表达进行了初步研究,结果提示大鼠成骨细胞在剪应力作用下,c-fos蛋白有明显的表达。

There is no difference for OBI in three groups.

成骨细胞指数在3组间差异无显著性。

RESULTS: BMP-2 was mainly found in the plasma of fibroblast, osteoblast, cementocyte, odontoblast separately.

结果:牙周膜成纤维细胞、成骨细胞、成牙骨质细胞及胶原纤维中均可见BMP-2阳性染色。

Weeks after operation, the expression of integrin β1 mRNA in OVX PII group was similar to JGG group.

术后24周,预防Ⅱ组成骨细胞的Itgβ1 mRNA 的表达水平与健骨颗粒组相近。

The tibiale cortex and bone cell have increased in examination with microscope. The number and function of osteoblast have increased, ossein was improved, number and function of osteoelast were controls in examination with electron microscope.

透射电镜的观察,则进一步证实了其作用机理可能是增加了成骨细胞的数量和活性,抑制了破骨细胞数量和活性,从而增加了骨形成,减少了骨吸收。

Fibroblast growth factor (FGF-1) is important for coordinating osteogenesis and angiogenesis of osseous repair.

纤维原细胞生长因素(FGF-1)为调整骨状的修理的成骨和angiogenesis是重要的。

All bones consist of living cells embedded in the mineralized organic matrix that makes up the osseous tissue.

所有骨都是由活的细胞组织,包容在矿物化有机质中,并构成骨

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呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

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