成纤维细胞的

Objective To provide a proliferation model of human oral mucosal fibroblasts for the study of repair mechanism on oral submucous fibrosis.

目的为研究口腔黏膜下纤维化的修复机制，建立体外人口腔黏膜成纤维细胞增殖模型。

Effects of salvia miltiorrhiza bunge on the proliferation and collagen synthesis in oral submucous fibrosis buccal fibroblasts［J］.

丹参对口腔黏膜下纤维化患者颊黏膜成纤维细胞增殖及胶原合成的影响［J］。

Methods Rat embryo dermal fibroblasts were cultivated on regenerated silk fibroin films in vitro adherently. The effect of regenerated silk fibroin films on morph, activity and growth of cells by viable cell counts and MTT colorimetric assay was observed.

采用静置贴壁培养法在再生丝素膜上体外培养鼠胚真皮层成纤维细胞，并用活细胞计数法及MTT比色法观察再生丝素膜对细胞的形态、功能和生长的影响。

Objective To study the effects of Aralia chinesis on the proliferation and viability of fibroblasts and on the production of the hyaluronic acid in the cultured supernatant, and to explore its anti-hepatofibrosis mechanism.

目的 探讨太白楤木对成纤维细胞增殖、活力及对培养上清中透明质酸产生的影响，研究太白楤木抗肝纤维化机制。

Results:(1) After 24 h action of negative electrets, electrophoretic mobility and cell number in S phase of 3T3 cells were significantly increased compared with those in control group.

结果：(1)负极性驻极体作用成纤维细胞使细胞的电泳率和S期内的细胞数显著增加。

Affect of kwoninone on fibroblastic proliferation, morphology and expression of TGF-β1 ［ABSTRACT］ AIM:To study

苦参素可通过抑制成纤维细胞增殖及TGF-β1的表达而起到抗肝纤维化作用。

The plasticity of NSCs was detected by the differentiating test. HESCs were induced into dopaminergic neurons by means of adding Sonic Hedgehog Peptide and fibroblast growth factor eight (FGF8) early under the condition of mocked microenvironment and different development stage of dopaminergic neurons in vivo ,meanwhile made comparison with traditional method . The marker of dopaminergic neurons was tested by immunocytochemistry and RT-PCR, the content of dopamine and its derivation homovanillic acid were measured by HPLC-ECD.

模拟体内多巴胺神经元分化发育的不同阶段及微环境，采用早期添加音猥因子及成纤维细胞生长因子-8(FGF8)的方法，诱导hESCs定向生成多巴胺能神经元，并与传统的诱导方法相比较，免疫荧光细胞化学和RT-PCR法检测多巴胺能神经元的标志，高效液相色谱法检测诱导后细胞及细胞培养上清液中多巴胺及其代谢产物高香草酸的含量。

IntroductionBasic fibroblast growth factor is a kind of cell growth factor which has a great effect on proliferation and differentiation to mesodermic cells.

前言 碱性成纤维细胞生长因子是一种对中胚层来源的细胞有强烈促增殖和分化作用的细胞生长因子。

Fig 3Lots of rough endoplasmic reticula, mitochondrid an d collagen in the cytoplasm of fibroblast in control group

图3对照组的瘢痕成纤维细胞粗面内质网、线粒体丰富，形态结构正常，周围胶原纤维较多TEM×5200

Itamin D from the skin and diet is metabolized in the lier to 25-hydroxyitamin D (Figure 1), which is used to determine a patient's itamin D status1,2,3,4; 25-hydroxyitamin D is metabolized in the kidneys by the enzyme 25-hydroxyitamin D-1-hydroxylase (CYP27B1) to its actie form, 1,25-dihydroxyitamin D.1,2,3,4 The renal production of 1,25-dihydroxyitamin D is tightly regulated by plasma parathyroid hormone leels and serum calcium and phosphorus leels.1,2,3,4 Fibroblast growth factor 23, secreted from the bone, causes the sodium–phosphate cotransporter to be internalized by the cells of the kidney and small intestine and also suppresses 1,25-dihydroxyitamin D synthesis.5 The efficiency of the absorption of renal calcium and of intestinal calcium and phosphorus is increased in the presence of 1,25-dihydroxyitamin D (Figure 1).2,3,6 It also induces the expression of the enzyme 25-hydroxyitamin D-24-hydroxylase (CYP24), which catabolizes both 25-hydroxyitamin D and 1,25-dihydroxyitamin D into biologically inactie, water-soluble calcitroic acid.2,3,4

从皮肤和食物来的维生素D在肝中代谢为25-羟基维生素D（图1），被用来决定病人体内维生素D情况的1，2，3，4；25-羟基维生素D在肾中被25-羟基维生素D1羟化酶（CYP27B1）转变为有活性的1，25-二羟基维生素D 。1，2，3，4由肾产生1，25-二羟基维生素D是被血浆甲状旁腺激素和血清钙，磷水平紧密调节。1，2，3，4由骨分泌的成纤维细胞生长因子23使钠磷协同转运蛋白被肾和小肠细胞内化及抑制1，25-二羟维生素D合成。5 在1，25-二羟基维生素D作用下肾和小肠吸收钙及磷的效率增高(图1)。2，3，6 它也包括25-羟四- 24 -羟化酶的表达(CYP24)，且将1，25二羟基维生素D和25羟基维生素D异化成无生物活性，水溶性的维生素D3-23羧酸。2，3，4

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新