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成纤维细胞

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Astragali many candies can be promoted into hyperplasia and collagenic formation of fibrous cells within the range of certain density, the ones that strengthened the wound ground substance are synthetic in order to promote the wound to heal.

细胞实验结果显示:黄芪多糖在一定的浓度范围内可促进成纤维细胞的增殖和胶原的合成,增强创伤基质的合成以促进伤口愈合。

Results Compared to those before treatment the volume of the implanted keloid of Group D began to decrease since 14 days after treatment time-dependently (all P 《 0.05), and the volumes of the other 3 groups continued to increase and peaked on days 21, 14, or 7 respectively (all P 《 0.05).Microscopy showed infiltration of a larger quantity of histiocyte in the keloid tissue, and more obvious collagen disorganization and apoptosis of fibroblasts in Group D than in the other 3 groups.The protein expression of Bcl-2 was more remarkable and the protein expression of BAX was less remarkable in Group D than iu the other 3 groups.

结果 用药前和用药后7、14、21、28、35 d,D组瘢痕疙瘩组织块体积(mm3)分别为173±5、172±5、147±5、125±6、112±7和84±9,从用药后14 d开始明显缩小(均P<0.05);而其他3组瘢痕疙瘩组织块体积均明显增大,从用约后7 d开始各时点测得的体积均明显大于D组(均P<0.05)。D组瘢痕疙瘩组织中有大量小鼠组织细胞浸润,胶原结构破坏和成纤维细胞凋亡明显重于其他3组,Bcl-2蛋门质表达明显弱于而Bax蛋白质表达明显强于其他3组。

The gene regulating sequence of human collagen type Ⅰ is located at 5'end and first intron. The carriers of reporting gene was made, and the function of promoter, enhancer and inhibiter was examined in this study. On the basis of above work, MBP ectopic expression carriers were further built. The result laid a foundation for investigating the feasibility, and validity to specially express MBP gene of human nervous system, in tendon fibroblast.

人Ⅰ型胶原基因调节序列位于5'端和第一内含子,本研究构建了带报告基因的载体并检测了其启动子,增强子和减弱子的功能,以此为基础,进一步构建了MBP异位表达载体,为探索在神经系统少突胶质细胞特异表达的人脑髓鞘碱性蛋白MBP基因转至肌腱成纤维细胞表达的可行性和有效性奠定了基础。

Kase S, Sugio K, Yamazaki K, et al. Expression of Ecadherin and betacatenin in human nonsmall cell lung cancer and the clinical significance[J].

CD44是分布极为广泛的细胞表面跨膜糖蛋白,在淋巴细胞,成纤维细胞表面均能检测到它的表达。

Methods: The basic fibroblast growth factor-based need to establish normal mitogen epidermal melanocyte cell culture, MTT method aloesin on black ...

利用碱性成纤维细胞生长因子为主要有丝分裂原建立正常人表皮黑素细胞培养系,MTT法测定芦荟苦素对黑。。。

Fibroblasts are mesenchymal cells which are derived from the embryonic mesoderm.

成纤维细胞是胚胎中胚层起源的间充质细胞。

Classical chromosomal breakage tests in blood detected 4, but analyses on fibroblasts were necessary to diagnose 3 more patients with hematopoietic somatic mosaicism.

血液经典染色体断裂测试发现了1名,但是有必要进行成纤维细胞的分析来诊断另外3位造血细胞嵌合体患者。

Objective To investigate the protective effects of recombinant human basic fibroblast growth factor on ischemic myocardium.

目的 探讨重组人碱性成纤维细胞生长因子在急性心肌缺血中对缺血心肌细胞的保护作用。

Results The mutation mouse model was established successfully, and inflammatory reaction such as bacterial infection、inflammatory cell infiltration、proliferation of fibroblast and neogenesis capillaries of neonatal mouse model can be observed with TEM in different stage.

结果 成功建立小鼠模型;在模型小鼠出生后的不同时段中,电镜下小鼠角膜基质内可见有细菌感染、炎症细胞浸润、成纤维细胞及新生毛细血管增生等炎症改变。

Objective: To investigate the nephrotoxicity of plumbagin on human embryonic kidney cell 293 in vitro and protective effects of acid fibroblast growth factor on the cells.

目的:观察白花丹素在体外对人胚肾细胞293的毒性,以及酸性成纤维细胞生长因子对白花丹素所致肾损伤的保护作用。

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