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成熟作用

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The Demosthenic facts of history has proved that Buddhism can influence the process of growth and maturity of a people, greatly boost its cultural development, and play a positive role in the stability and harmony of a society.

雄辩的历史事实证明,佛教能够影响一个民族的成长、成熟过程,也能够对其文化的发展发挥巨大的促进作用,也能对社会的稳定、和谐产生积极的作用。

Background and objective: Rhomotoxin, the active constituent of Rhododendron molle belonging to Ericaceae, has the effects of decreasing blood pressure and slowing heart rate. These effects can exacerbate and remain 0.5-1 hour after drug withdrawal, which is prone to cause lower blood pressure even shock.

背景与目的八厘麻毒素(rhomotoxin,RTX)系从植物杜鹃花科羊踯躅成熟果实中提取的有效成份,具有较强的降压、减慢心率作用,但其降压作用在停药后0.5-1小时仍继续加深,易引起降压过度而导致休克,同时血中浓度检测困难,不易监控,临床上应用较难掌握。

The results showed that TNF-α effectively inhibited preadipocyte proliferation stimulated by insulin and decreased lipogenesis through inhibiting stimulation of insulin on transcriptional expressions of lipogenic genes such as acetyl-CoA carboxylase α(ACC1), fatty acid synthase, sterol regulatory element binding protein-1c in adipocytes, suggesting that TNF-α is a effective inhibitor of adipogenesis in adipose tissue.

结果表明,TNF-α可有效抑制胰岛素对原代培养大鼠前体脂肪细胞增殖的促进作用,并通过抑制胰岛素对转录因子SREBP-1c和脂肪酸合酶FAS及ACC1基因转录表达的促进作用,减少脂肪酸的生物合成,抑制成熟脂肪细胞的脂肪生成,证明TNF-α是动物脂肪形成的有效抑制因子。

Despite of its important role during embryogenesis and reproductive development,more and more studies implied a critical role for Rhox5 on the determination and differentiation during myogenesis.

除在生殖系统的发育、精子的形成和成熟过程中发挥重要的作用外,多项研究表明其在肌细胞的发生和分化中担任重要角色,有可能作为MyoD基因的上游调控子或者和其他转录因子协同作用,调控肌细胞的早期发生和分化事件。

Orexin A(100 and 1000 nM) stimulated the release of GnRH from hypothalamic explants harvested from prepuberal swine.However,only 1000 nM orexin B could stimulated the release of GnRH from the hypothalamic explants harvested from prepuberal swine.

五、Orexin对性成熟青年母猪下丘脑组织-垂体-卵巢轴作用的体外研究为探讨orexin在生殖调节中直接作用的靶位点,我们在体外培养了猪下丘脑脑片、垂体和卵巢细胞,研究了orexin A和orexin B在体外对下丘脑、腺垂体和卵巢GnRH、LH和E2释放的影响。

Results indicated that the GABAnergic system inhibition and pre-synaptic transmitter exhaustion may play an important role in short-term plasticity. And the short-term depression in thalamocortical visual pathway was strengthened when the cortex circuit get mature.

结果表明:GABA能系统的抑制作用和突触前递质衰竭很可能是决定该回路短时程抑制特性的主要因素;幼年大鼠与成年大鼠视觉系统短时程突触可塑性的对比研究表明,随着皮层回路的成熟,视觉丘脑至皮层通路的短时程突触抑制作用越来越强。

PEM and crura may have a role in anti-reflux mechanism, and it decreases as the child grows.

虽然PEM和食管裂孔肌在婴儿可能起一定的抗返流作用,但在抗返流机制成熟过程中起的作用将越来越小。

Vascular endothelial growth factoris a new kind of blood vessel active factors was finded in recent years. It not only plays a very important role in the process of micrangium proliferation but also contributs to the stabilizing, maturating and refraining from apoptosis of nascent micrangium, it participates the vascular endothelial cell through specific binding with corresponding receptor.

血管内皮生长因子(vascular endothelial growth factor, VEGF)是近年来新发现的血管活性因子,通过与相应受体结合特异性的作用于血管内皮细胞,不仅在毛细血管增生中起着十分重要的作用,而且对于稳定新生的毛细血管,使之成熟,避免凋亡具有重要意义。

The number of BrdU labeling in the nucleus was remarked increasing onbFGF-treated pancreatitis rats than pancreatitis rats without bFGF treatment. And there was a significant difference.(P.01)ConclusionThe result of the study has demonstrated the effective therapeutic effects on acute edematous pancreatitis rats, which induces proliferation of immature acinar cells, facilitates the repair of damaged pancreatic tissues and reconstitutes tissue integrity.

兔疫组化结果显示bFGF治疗组大鼠具有BrdU标记的细胞核胰腺细胞数明显多于非治疗对照组大鼠,两者在统计学上具有显著性差异Oeq.of人结论实验结果表明bFGF对急性水肿性胰腺炎大鼠具有明显的治疗作用,它的治疗作用具体表现在诱导非成熟的胰腺细胞分化增殖,促进受损胰腺组织修复,重建组织完整性。

To identify the possible cytokines which may be invovled in this process,we used neutralizing antibodies of DKK-1 and TGF-βto treat AFMSC when cocultured with K562 cells and found that it was DKK-1 not TGF-βthat participated the process.

由于成熟的基质细胞不存在抑制肿瘤增殖的作用,我们推测可能是AFMSC的内在特性决定了这种作用的发挥。

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