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Histological structures of bursas of Fabricius were observed at the different developmental stages from chicken embryoes to chickens. The results were as follows. The bursa of Fabricius began to develop on the 13th day of post-hatching and its cell aggregated into the nodosity clique underneath the epithelium mucosae. On the 15th day of post-hatching, those cell cliques were surrounded by the flat epithelium and formed the basic structure of folliculus lymphaticus. The number of lymphocytes in the folliculus lymphaticus increased gradually, and the medulla and cortex of a majority of folliculus were not discriminated obviously. Until on the 7th day for chickens, the medulla and cortex of folliculus formed completely and the number of folliculus increased significantly. From 21 to 35 days old, the folliculus lymphaticus transformed from polygon into rectangle. Mucosa epithelial cells increased gradually and their cytoblasts arranged compactly into aline in the basilar part on the 35th day.

本研究观察了从鸡胚到出壳后的不同生长发育阶段法氏囊的组织结构,结果表明:胚胎13日龄时,法氏囊开始发育,粘膜上皮下形成结节状细胞集团;胚胎15日龄,聚集的细胞集团形成初始的淋巴滤泡;胚胎18日龄到出壳后1日龄,滤泡内淋巴细胞数量增多,多数滤泡髓质和皮质界限仍不明显;7日龄雏鸡法氏囊髓质皮质分界清晰,滤泡数量显著增多;21日龄到35日龄,滤泡由多边形逐渐转变成长方形;在35日龄时,粘膜上皮细胞逐渐增多,排列紧密,细胞核紧密排列成直线位于基底部。

We describe a case of NLPHL showing a variant histologic pattern characterized by small and large clusters of lymphocyte predominance cells within nodules defined by follicular dendritic cell meshworks, associated with numerous neutrophils and areas of internodular fibrosis. Focally, the neoplastic cells had lacunar cell-like cytologic features.

在此,我们描述一例组织形态特殊的NLPHL,其形态学表现为以淋巴细胞为主的细胞排列成大小不等的结节,结节均由滤泡树突状细胞网网罗,结节内见中性粒细胞浸润,部分结节间见纤维化,局灶瘤细胞呈陷窝样。

Microscopic examination revealed preservation of the architecture of the testicular parenchyma, typically with hemorrhage and edema, with patchy inflammation in the form of a lymphohistiocytic infiltrate within seminiferous tubules and also between tubules. The intratubular infiltrate usually predominated. Immunohistochemical studies, performed in 7 cases showed a mixture of CD68+ histiocytes and CD3+ T cells, with few B cells (CD20+) and few granulocytes.

显微镜下,病变保留了睾丸实质的结构,出血、水肿显著,淋巴细胞和组织细胞组成的炎细胞斑片状浸润至曲细精管内和管间,而以管内更为显著。7例做了免疫组化,显示炎细胞由CD68阳性的组织细胞和CD3阳性的T细胞混合而成,B细胞(CD20+)和粒细胞罕见。

Mild leukopenia was observed in 21.4% of patients, and lymphopenia in 68.1% of adult patients and 92.3% of children.

观察到21.4%的病人有轻度白细胞减少,在68.1%成人和92.3%的儿童有淋巴细胞减少。

It proliferates into clones that produce a continuous supply of a specific antibody .

杂种在实验室里制造的一种由一个能产生抗体的淋巴细胞与一个骨髓瘤结合而成的。

Lymphocyte preparations were cocultured with HCV replicon (FCA1) and control (Huh7) cells labeled with 51Cr.

淋巴细胞准备是由HCV复制子(FCA1)和标记51铬的对照组细胞(Huh7)共同培养而成的。

Immunohistochemical staining revealed that the reactivities of mAbs to the lymphocyte cells in tonsil and colon tissues, to fibroblast cells in foreskin tissues, to macrophages in lung tissues were observed.

免疫组化染色表明,mAb与人扁桃体、结肠组织中的淋巴细胞、包皮组织中的成纤维细胞、肺组织中的巨噬细胞反应呈阳性。

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