成核

Simultaneously we prepared benzimidazolines with two methods by the reducton of benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 9 kind of tetrahydro-β-carboline starting from carboxylic aicd and halid. A convenient synthetic method for preparing tetrahydro-β-carboline was provided.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了9种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以色胺作为接受一碳转移的亲核试剂，完成9种四氢-β-咔啉类化合物的新合成方法研究。

By using multi-dimensional nuclear magnetic resonance method we have studied the folding mechanism of staphylococcal nuclease in vitro; the tertiary interactions for folding of SNase fragments into native-like conformation; the interaction between SNase N- and C-terminal subunits; the relationship of enzyme activity with folding and dynamic states of SNase; the structural properties of enzyme protein while exert its function. We have studied the internal motions of thermophilic Archaea protein Ssh10b and mechanism of its heat-resistance using the NMR 1H-15N relaxation and H/D exchange methods. We have determined the 3D solution structure of human translationally controlled tumor protein TCTP and the Ca2+-binding site; determined the 3D crystal structure of human mitoNEET, a novel protein from distinct groups of iron-sulfur proteins; determined the 3D solution structure of a novel chromatin protein Cren7. Determination of SNase-DNA and Archaea protein-DNA complex structures are in progress.

运用异核多维核磁共振方法研究了金黄色葡萄球菌酶体外折叠机制，酶蛋白片段体外折叠成类天然溶液三维构象的三级相互作用力，酶蛋白亚基间的相互作用，酶蛋白的折叠以及内运动状态与酶活力的关系，酶蛋白发挥功能时的结构特性；运用NMR的1H-15N 驰豫和H/D交换方法研究了嗜热古菌蛋白质Ssh10b双体结构内运动特性，热稳定性机制；确定了人翻译控制的肿瘤蛋白TCTP蛋白的溶液三维结构及其钙离子的结合部位；确定了一类新的铁硫蛋白家族蛋白人线粒体膜上mitoNEET蛋白的晶体结构；确定了一个新型的染色质蛋白Cren7的溶液三维结构；正在研究金黄色葡萄球菌酶及嗜热古菌蛋白质与DNA复合体的溶液三维结构。

Nuke war is one of the most distructive disasters to human world next to the " artificial Black Hole ", capable of vaporing any person in its explosion range within some thousandths of a second .

理论上，核战是紧随&人工黑洞&之后，毁灭人类速度最快的灾难之一，处于核弹爆炸范围中的人，只要千分之几秒，就会被蒸发成一团气体。

The Baoertu copper deposit is located in the Metamorphic rocks in the anticlines crest of Aimutaiwula, which located in the east part of the contact belt between South Tianshan and Middle Tianshan in the plate of Tarim, and on the south of the great faults of Wu\'wamen-Bao\'ertu. And the Baoertu copper deposit is one of the mainly metallogenetic areas, which are polymetallic metallogenic belts in South Tianshan-Haerke-Kumishenjin, including gold, copper, lead, zincum.

包尔图铜矿位于塔里木板块北缘南天山与中天山接触带的东段，乌瓦门-包尔图大断裂南侧，分布于艾木太乌拉背斜核部的一套变质岩中，是南天山-哈尔克-库米什金、铜、铅、锌多金属成矿带主要成矿区之一。

Simultaneously we prepared benzimidazolines with two methods by the of reduction benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 13 kind of tetrahydroisoquinoline starting from carboxylic aicd and halid, gave a new idea of the synthesis for new drugs.It can make many kind ofβ-carboline alkaloids which have bioactivity to antibacterium, antivirus and antitumor to start from 1,2,3,4-tetrahydro -β-carboline.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了13种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以2-(3，4-二甲氧基苯基)乙胺作为接收一碳转移的亲核试剂，完成了13种重要的四氢异喹啉类化合物的新合成方法研究。

Pass the time of day;spend the time of day

书旁一大碟枇杷和皮核，想是效成等自己消闲吃的。

AIM: To investigate the influences of ablating the nucleus accumbens with stereotactic surgery on 75 opioid addicts personalities 10 d later.

目的：探讨实施立体定向双侧伏核微创射频毁损术10 d后阿片类药物成瘾者人格特征的变化。

We set up the angular momentum conservation model of wind accretion of Ba stars, and then derive the change equations of the orbital elements. Finally, combining the heavy element nucleosynthesis of AGB stars, we creatively calculate the heavy-element overabundances of barium stars in a self-consistent manner adopting accreting and mixing on successive occasions.

我们建立了Ba星形成的星风吸积的角动量守恒模型，推导出其轨道根数的变化方程，并结合AGB星的重元素核合成，通过逐次脉冲吸积与混合，自洽地计算出Ba星的重元素超丰。

As the nuclear burning moves outward to the fresh material in a shell surrounding the core, the star bloats into a so-called red giant.

当核燃烧向外进行到核心周边壳层的新物质时，恒星会膨胀成所谓的红巨星。

The area has a central core of hard volcanic rocks carved by ancient glaciers into spectacular cliffs, precipices and flooded glaciated valleys.

这个地区有个火山硬岩的中心核被古代的冰河雕刻成壮观的峭壁、悬崖与被冰河淹埋造成的山谷。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。