成年

IUGR can induce the obstacle of signal transduction and effecter molecule by impacting on IRS?2,which might be one of the molecular mechanisms of IUGR with insulin resistance at adult.

宫内发育迟缓对胰岛β细胞上胰岛素信号分子胰岛素受体底物2的影响导致胰岛素信号转导通路障碍，这可能是胎儿宫内发育迟缓鼠成年后发生胰岛素抵抗的原因之一。

Objective To establish a database for biological and electrocardiographic parameters of Beagle dogs used for pharmacological and toxicological studies.

目的 测定正常Beagle犬生理指标，比较不同性别间各参数的差异，以建立健康成年Beagle犬相关生理学参数的基础正常值。

Methods Twenty - five female SD mice were averagely and randomly divided into control group, model group, medication group, electropuncture group, and electropuncture combined with medication group.

将25只成年 SD 雌性大鼠随机分为正常组、模型组、电针组，药物组，针药结合组。

METHODS:The distribution changes of N CAM at flatfish muscle neuromuscular junction of rat in its embryon phase,14 day after birth,adulthood and 10,20 and 30 days after its L5 lumber nerve root injury were observed by immunohistochemistry and confocal laser scanning microscopy technologies.

采用免疫组织化学方法和激光共聚焦显微扫描技术，观察了大鼠胚胎期，出生后14d，成年期以及L5神经根受压后10，20，和30d，大鼠比目鱼肌神经肌肉接头部N-CAM的分布变化。

To understand global features of gene expression changes during in itro neural differentiation, we carried out the microarray analysis of embryonic stem cells, embryonal carcinoma cells, and adult neural stem/progenitor cells.

中文摘要：为了了解在体外神经分化期间基因表达改变的全面特征，我们对胚胎干细胞，胚胎性癌细胞和成年的神经干/祖细胞进行了微阵列分析。

And then the author tested the Micro- VOL Evaluation model with empiristic study to work out all ages'VOL range with the analysis of statistics data, that is, a juvenile's VOL is about200,000 to 300,000 yuan, an manual labor's VOL is on an average of about 700,000 yuan, and an intellectual employee's VOL is about 1040,000 yuan on average.

估算出接近成年年龄的未成年人生命力价值约为20-30万元，体力劳动者生命价值平均约为70万元；脑力劳动者生命力价值平均约为104万元。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan （the average body weight was 25～30 kg）were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P＜001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P＜001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P＜001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P＜001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系，探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只，平均体重25～30 kg。随机分为3组：正常对照组10只，模型组10只（球囊内膜剥脱加高胆固醇饮食），治疗组10只（球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d）。结果兔髂动脉造影、血管病理图像分析检测结果：①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比，各组之间有显著性差异(P＜001)。②免疫组化分析：模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组（P＜001）；复方丹参滴丸组MMP2、MMP9的表达低于模型组，而TIMP1、TIMP2的表达高于模型组；TIMP1/MMP2、TIMP2/MMP9明显增加，差异有显著性（P＜001）。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896，P＜001)。结论 MMP和TIMP在再狭窄形成中起重要作用；复方丹参滴丸能够明显抑制血管损伤后的内膜增生，可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生，而减少内膜的增生。

The main content includes the metabolism and energy balance; the ontogenesis of biological rhythms; the development of nervous system and endocrinological regulating mechanisms; the factors affecting the fetal development and growth; the relationships of fetal development to the reproductive and reproductive abilities of adult animals.

主要内容包括胎儿的新陈代谢与能量平衡；生物节律的形成；胚胎期神经系统和主要内分泌器官的发生和调节机制的建立；影响胚胎发生发育的主要因素以及动物的发生发育与成年动物生产与生殖能力的关系。

The positive hybridizations with COCH gene cRNA probe were detected in the mouse mesenchymic cell surroundding the endolymphic sac epithelium, the level of expression was similar to the fibrocytes underlying crista ampullaris sense epithellium, and inferior to the fibrocytes of spiral ligament.

成年小鼠内淋巴囊周围间质细胞COCH基因表达阳性，其原位杂交染色平均积分光密度为0.4±0.25（〓±SD，单位：U／mm〓），与壶腹嵴感觉上皮下间质细胞的0.47±0.21相似，弱于耳蜗螺旋韧带成纤维细胞的0.77±0.19。

There were obvious differences in ultrastructure of the lymphatic endothelia between the embryonic and the adult rats.

4胚胎期与成年期肠系膜淋巴管内皮的超微结构有明显差异。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。