戊巴比妥

A salt or ester of carbamic acid, especially one used as an insecticide.

一种戊巴比妥酸盐（商品名nembutal）用作镇静药和催眠和反间歇性痉挛。

MPG has the actions of enhancing myocardial contraction, improving myocardial compliancy and left ventricular systolic and diostolic function and increasing cardiac output and arterial blood pressure in heart failure cats caused by Pentobarbital sodium.These show MPG is beneficial to releasing heart failure.

甲基葡萄糖苷对戊巴比妥钠诱发的实验性心衰猫具有加强心肌收缩力、改善心肌顺应性和左室舒缩功能、增加心排血量、升高动脉血压的作用。

After heart perfusion, the spinal cord and brainstem were removed, and post-fixed overnight, then coronally sliced into 25μm thick of each piece.

取出后过量戊巴比妥钠麻醉，心脏灌流，取脊髓和脑干，后固定过夜，冰冻切片，片厚25μm。

METHOD: The following tests were made:①test with of hemopoietic inhibition induced by cyclophosphamide on mice,②Carban particles clearance test,③Erythrolysin formetien test,④Swimming test,⑤Hypoxia test,⑥Sedation test,⑦Hypnosis test.

①由环磷酸胺引起的小鼠造血系统抑制模型；②小鼠碳粒廓清试验；③小鼠溶血素形成试验；④小鼠游泳试验；⑤小鼠耐缺氧试验；⑥小鼠旷野活动试验；⑦由戊巴比妥钠引起的小鼠催眠模型。

The extremities were titanic, and there was no response to touch stimulations.Our results suggested that Pentobarbital sodium inhibited neuronal firing through GABA_A receptors, therefore the local field potentials and neural firing rates were inhibited; Urethane acted on many kinds of receptors including inhibitory and excitory ones, so the local field potentials did not change significantly; however, because of the multiform receptors on the neurons, the changing of firing rates to different neurons were not the same; Ketamine mainly acted on the NMDA receptors, therefore the local field potentials and neural firing rates were enhanced, and most neural firing rates would be increased.

从这三种麻醉剂的底层作用机制来看，戊巴比妥钠通过作用于GABAA受体对神经细胞发挥抑制性作用，因此表现为场电位和神经元放电的降低；氨基甲酸乙酯同时作用于多种受体通道，既有兴奋性受体，也有抑制性受体，因此，对场电位的影响不大，但对单个神经元来说，每个神经细胞上的受体通道分布差异较大，因此，单个神经元的放电频率变化会有所不同；盐酸氯胺酮主要作用于兴奋性的NMDA受体，故整体场电位活性增加，多数神经元的放电频率也会有所升高。

GroupⅤwas perfused with pentobarbital sodium and nikethamide(5mmol/L).

I组用Kreb氏液洗脱，Ⅱ-Ⅴ组用戊巴比妥钠Kreb氏液洗脱。

Methods The effects of Wuweizi Ningshen Oral Liquid on sedation,hypnotics and anti-convulsion in mice were observed by counting spontaneous behavior,prolonging sleeping time cooperated with pentobarbital sodium and antagonizing convulsion induced by Nikethamide injection.

采用镇静、催眠、抗惊厥实验观察五味子宁神口服液对小鼠自主活动的影响，协同戊巴比妥钠对小鼠的催眠作用及对小鼠尼可刹米惊厥的抑制作用。

MethodsThe effects of Wuweizi Ningshen Oral Liquid on sedation,hypnotics and anti-convulsion in mice were observed by counting spontaneous behavior,prolonging sleeping time cooperated with pentobarbital sodium and antagonizing convulsion induced by Nikethamide injection.

方法采用镇静、催眠、抗惊厥实验观察五味子宁神口服液对小鼠自主活动的影响，协同戊巴比妥钠对小鼠的催眠作用及对小鼠尼可刹米惊厥的抑制作用。

We previously estimated that the decreasein nociceptive reflex threshold is maximal at pentobarbitalconcentrations of approximately 5 M.

我们此前估计伤害反射阈值的下降最大出现在戊巴比妥浓度约为5 M 时。

METHODS: In fed rats, the effects of pentobarbital,isoflurane, sevoflurane, ketamine-medetomidine-atropine, and sufentanil-propofol-morphine on the cardiaccellular localization of hexokinase and levels of plasmaglucose and insulin were determined and compared with valuesobtained in nonanesthetized animals.

测定戊巴比妥、异氟烷、七氟烷、氯胺酮-美托咪定-阿托品和苏芬太尼-丙泊酚-吗啡麻醉下人工饲养大鼠心肌细胞己糖激酶定位和血浆葡萄糖及胰岛素浓度，并将之与未麻醉大鼠的对应参数作对比。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。