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戊巴比妥

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ResultsThe Ziziphus jujube leaf extract could inhibit autonomic activities of the mice, prolong the sleep time induced by pentobarbital sodium, enhance the rate of falling asleep induced by barbital sodium and inhibit the central stimulating effects induced by amphetamine.

结果酸枣叶提取物可对小鼠自主活动呈明显抑制作用,延长戊巴比妥钠诱导的小鼠睡眠时间,增加巴比妥钠诱导的小鼠睡眠发生率和缩短巴比妥钠诱导的小鼠睡眠潜伏期。抑制苯丙胺的中枢兴奋作用。

Solid phase extraction and gas chromatography-mass spectrometric method have been ~developed for the determination of barbital, amobarbital and phenobarbital residues in pork.

采用HP5毛细管柱分离,电子轰击电离源质谱选择离子模式检测(巴比妥m/z126,169,183,184;异戊巴比妥m/z169、170、184、226;苯巴比妥m/z175、232、245、260;dwelltime80s),外标法定量(定量离子m/z分别为169、169和232)。

So the liver increases the amount of enzymes needed to remove barbiturates from the blood and the central nervous system just becomes used to the barbiturate.

也就是说肝脏中会增加分解酶以便将血液中的"戊巴比妥"分解掉,或者中枢神经系统变得对"戊巴比妥"适应了。

The effect of sleep improvement of the three dosages(570 mg/kg,1000 mg/kg and 2000 mg/kg)of Semen Ziziphi Spinosae was studied by the experiments of sleep-induced directly, prolonging sleeping time induced by pentobarbital sodium, affecting mouse sleeping rate under the threshold hypnogenesis dosage of pentobarbital sodium and affecting sleeping delitescence induced by tobarbital sodium. The content of 5-HT in the brain of mouse was measured by fluorescence assay.

通过直接睡眠实验、延长戊巴比妥钠睡眠时间实验、戊巴比妥钠阈下催眠剂量实验和巴比妥钠睡眠潜伏期实验,比较低、中、高3个剂量(570 ,1 000 及2 000 mg/kg)酸枣仁粉剂对小鼠睡眠的影响,并且用荧光法测定小鼠脑中 5-羟色胺含量。

Results The result showed that 0.7% and 1% sodium pentobarbital anesthesia duration was too short, 1.5% pentobarbital sodium easily made animal deaths, and 10% chloral hydrate used for anesthesia in mice was appropriate. And the glass cannula was more suitable than adhesive bandages for enswathement.

结果 0.7%和1%戊巴比妥钠麻醉持续时间过短,1.5%戊巴比妥钠和10%水合氯醛能维持足够手术操作所需的时间,但1.5%戊巴比妥钠易导致动物死亡,故采用10%水合氯醛麻醉小鼠较合适;玻璃套管法包扎的效果较创可贴法为好且更简便。

MethodsIts effect on sleep was observed through the experiments of sleep induced directly,prolonging sleeping time induced by pentobarbital sodium,affecting sleeping rate under the threshold hypnogenesis dosage of pentobarbital sodium,shortening sleep delitescence induced by tobarbital sodium.

方法通过直接睡眠实验、延长戊巴比妥钠睡眠时间、戊巴比妥钠阈下催眠剂量实验和缩短巴比妥钠睡眠潜伏期实验观察灵芝提取物对睡眠的作用。

If she did have the Nembutal from a few days earlier then the amount she had on hand would be 50 Nembutal total.

假如梦露确实在她手中这瓶药之前数日得到了"戊巴比妥"胶囊,那么她手中就有可能有50个"戊巴比妥"胶囊。

Nembutal Sodium exerts a depressant action on the CNS and shares the sedative-hypnotic actions typical of the barbiturates.

戊巴比妥钠对中枢神经系统产生抑制作用,并显示戊巴比妥类特有的镇静催眠作用。

Methods The compound preparation was administered intragastrically in mice, whose spontaneous activity was observed along with their tolerance of the preparation after long-term administration. The hypnotic effect of the compound was assessed by investigating the changes in the pentobarbital sodium-induced sleeping. The compound was tested for its antiseizure effect in mice with pentetrazole-induced clonic and tonic convulsion. Diazepam was used as the standard control in all experiments.

利用光电计数法观察灌胃给予复方酸枣仁油栀子油对小鼠自发活动的影响,以及长期使用药物对小鼠耐受性的影响;利用延长戊巴比妥钠睡眠时间实验和戊巴比妥钠阈下催眠剂量实验,观察复方酸枣仁油栀子油的催眠作用;利用戊四氮诱发小鼠阵挛性、强直性惊厥观察复方酸枣仁油栀子油的抗惊厥作用;本实验用地西泮进行平行对照实验,并进行了组方设计和实验。

ResultsThe Ziziphus jujube leaf extract could inhibit autonomic activities of the mice, prolong the sleep time induced by pentobarbital sodium, enhance the rate of falling asleep induced by barbital sodium and inhibit the central stimulating effects induced by amphetamine.

结果酸枣叶提取物可对小鼠自主活动呈明显抑制作用,延长戊巴比妥钠诱导的小鼠睡眠时间,增加巴比妥钠诱导的小鼠睡眠发生率和缩短巴比妥钠诱导的小鼠睡眠潜伏期。

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