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Result:There were 166 cases that were abnormal in 175 cases ,the incidence of peptic ulcer was 15.43%, the incidence of duodenal ulcer was higher than gastric ulcer in children.the incidence of chronic gastritis and chronic duodenitis was 94.86%, the incidence of chronic gastritis was significantly higher than chronic duodenitis, chronic superficial gastritis, bile reflux gastritis see most, chronic erosion hemorrhage of chronic gastritis and chronic duodenitis was not uncommon. Helicobacter pylori testing positive rate of 59.04%, peptic ulcer cases were all positive detection of helicobacter pylori.

结果:175例胃镜检查有异常者为166例,消化性溃疡发生率为15.43%,小儿十二指肠溃疡发生率高于胃溃疡,并以十二指肠球部溃疡多见,胃溃疡以胃窦溃疡多见,胃、十二指肠炎的发生率为94.86%,小儿慢性胃炎发生率明显高于慢性十二指肠炎,其中以慢性浅表性胃炎、胆汁返流性胃炎最多见,慢性糜烂出血性胃、十二指肠炎也不少见,幽门螺杆菌检测阳性率为59.04%,其中消化性溃疡病例检测幽门螺杆菌均为阳性。

Also, few centers perform pancreatectomy for nonmalignant disease because of problems with fragile diabetes, especially in alcoholics.

个人评论:单纯就其统计学意义来说,研究人员将接受手术的胰腺癌和慢性胰腺炎患者的死亡率进行了比较,统计表明手术治疗慢性胰腺炎手术死亡率低于胰腺癌患者,但这仍不能作为建议手术治疗慢性胰腺炎的依据,因为没有对慢性胰腺炎患者中手术治疗和非手术治疗患者的预后和死亡率进行对比,我们还无法认定手术治疗慢性胰腺炎效果优于非手术治疗。

Objective To examine the value of Edaravone in the treatment of vascular dementia through ethologic and pathologic changes induced by chronic cerebral ischemiaMethods Wistar rats were randomly divided into sham operated group,model group,edaravone group and duxil groupThe chronic cerebral hypoperfusion models were made by permanent bilateral occlusion of both common carotid arteriesThe memory ability and ultramicrostructure of brain tissue were observedResults The escape latencies in model group were more significantly prolonged than that in the other groups (P<005)But there was no significant difference between edaravone and duxil groupAnd pathologic changes observed by electron microscope in nerve cell of edaravone group and duxil group and model group were fairly light than that in sham operated groupEdaravone group had increased mitochondrium and frontal membranous synaptic vesicle and more productive metabolic activityConclusions Edaravone can lessen injures of hippocampal neurons loss to improve the spatial learning and memory abilitiesAnd it is proved further that edaravone can treat VD

目的 观察依达拉奉对慢性缺血致血管性痴呆大鼠行为学及形态学的影响,探讨依达拉奉在治疗VD中的应用价值。方法实验分假手术组、模型组及都可喜对照组及依达拉奉治疗组,应用双侧颈总动脉结扎方法制备慢性脑缺血大鼠痴呆模型,观察各组大鼠的记忆功能及脑组织超微结构改变。结果缺血组水迷宫表现同对照组、都可喜组及依达拉奉组相比有显著差异(P<005),依达拉奉组与都可喜组相比未见显著差异。同时电镜观察结果也发现依达拉奉组及都可喜组与模型组及假手术组相比神经细胞病理改变较轻,且依达拉奉组线粒体及前膜突触小泡增多,代谢活动较都可喜组旺盛。结论依达拉奉可能通过减轻海马神经元的损伤来改善慢性脑缺血大鼠空间学习记忆障碍,证明依达拉奉对慢性缺血致VD大鼠具有治疗作用。

Methods Twenty four patients with chronic renal diseases and 48 healthy volunteers were examined with SS-EPI DWI at 3.0T MR. In chronic renal disease group, RIF of 14 patients who received renal biopsy was determined as grade Ⅰ and Ⅱ based on the tubule- interstitial damage degree, while RIF of 10 patients with uremia, who did not receive biopsy but had nephrogenic renal atrophy, was categorized as grade Ⅲ.

对照组(48例正常志愿者)和慢性肾病组(24例慢性肾脏疾病患者)在肾脏常规MR扫描后行DWI扫描,慢性肾病组14例行穿刺活检,根据病理结果将肾小管间质损害程度分为Ⅰ、Ⅱ级;另10例肾脏体积缩小的慢性肾功能衰竭尿毒症期患者定为Ⅲ级。

Under the same concentration, tadalafil induce higher ratio of relation responses in the smooth muscles of CRF rabbit cavernosal strips, compared with papaverine and sodium nitroprussiate, with most significant difference occurring under the concentration indicators of 10-5 mol/L and 10-4 mol/L (P.01). Conclusions The effects of tadalafil on relaxation responses in CRF rabbit cavernosal strips highly depend on its concentration. The effect of tadalafil on relaxation responses in CRF rabbit cavernosal strips is better than that of papaverine and sodium nitroprussiate. Tadalafil may be an effective drug for treating CRF reduced erection dysfunction.

同一浓度下,他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比与罂粟碱、硝普钠相比较,舒张百分比均大于罂粟碱和硝普钠,且在10~(-5)mol/L、10~(-4)mol/L浓度,他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比,与罂粟碱、硝普钠相比较有显著性差异(P<0.01)结论他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响具有浓度依赖性,他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响优于罂粟碱及硝普钠,他达拉非可能是治疗慢性肾功能衰竭性阴茎勃起功能障碍的理想药物。

Objective: This thesis mainly discussed the clinical research of chronic nonbacterial prostatitis by method of Qing Re Li Shi and Bu Shen Qing Li treatment. We observed traditional Chinese medicine clinical effect of CNP by different treatment,and discussed the pathogenesis, pathphysiology, treatment method of CNP and the mechanism of traditional Chinese medicine.

目的:本文拟通过补肾清利法对慢性非细菌性前列腺炎治疗的临床研究,观察其对慢性非细菌性前列腺炎的疗效及观察指标的影响,并与清热利湿法作对照治疗,探讨补肾法在慢性非细菌性前列腺炎中的治疗作用,以及中医药治疗慢性非细菌性前列腺炎的作用机理。

The results had positive cultures of the pyloric spiroid bacteria in 59 of 98 samples.

结果:98份样本中,培养出幽门螺旋菌59例,其中慢性胃炎阳性率62.7%(浅表性胃炎阳性率最高,达91.1%),消化性溃疡阳性率57.4%;在慢性胃炎患者胃窦粘膜病理切片中可检出,仍以慢性浅表性胃炎检出率最高达91.1%。15例幽门螺旋菌阳性消化性的溃疡患者,经TDB治疗4周后有12例细菌消失,并伴有组织形态学改变。

In orde to probe the prevention and the therapeutic mechanism for Chinese medicine, and provide the laboratory basis for the incidence theory on chronic rhinitis. A method of using smoking with SO2, and submuscular injection with esbrogen on guinea pigs to establish chronic rbinitis model with the deficiency of lung Qi is introduced, And constrasted with the method of purly using smoking with SO2, or submuscuiar injection with estrogen. It shows the conbination of using smoking with SO2, and submuscular inj...

为了探索中医药防治慢性鼻炎的机理及为中医学对有关慢性鼻炎发病机理的认识提供实验室依据,本文在文献报道基础上,采用SO2及雌激素共同作用制作肺气虚豚鼠实验性慢性鼻炎模型,并与单纯SO2染毒或单独雌激素肌注的方法进行了对比研究,结果表明,采用SO2染毒及雌激素肌注的方法可引起鼻粘膜慢性非特异性炎症改变;动物生态属肺气虚型;且优于单纯采用SO2染毒及单纯雌激素肌注造模。

Strategies and approaches of the integrated traditional Chinese and Western medicine in preventing and treating CKD are:(1) enhance the study of optimized scheme for single entity;(2) accelerate the step of new drug exploitation;(3) augment the study of action mechanism of traditional Chinese medicine in treating CKD;(4) strengthen the study of the mechanism of Chinese crude drug which is poisonous to kidney and its prevention and cure;(5) utilize the systems biology to study the essence of kidney;(6) establish a guideline for integrated traditional Chinese and Western medicine in prevention and treatment of CKD;(7) preach up the general knowledge of CKD, pay attention to mass screening and early prevention of CKD.

慢性肾脏病已经成为全球性公共健康问题,其患病率和病死率高,并明显增加心血管疾病的危险性,产生巨额的医疗费用。中西医结合防治慢性肾脏病有优势,但也存在不少困惑。中西医结合防治慢性肾脏病的思路和方法是:(1)加强单病种优化方案的研究;(2)加强确有疗效的新药开发研究;(3)加强中医药治疗肾脏病作用机制的研究;(4)加强有毒中药肾损害的机制及防治研究;(5)利用系统生物学的方法,探索中医肾本质的研究;(6)组织编写《慢性肾脏病中西医结合防治指南》;(7)大力宣传,重视普查,早期预防。

Objective:To observe the changing trend of chronic di seases incidence rate in Chengdu and provide scientific data for effective int erven tion of chronic diseases Methods:Used EXCEL/SAS software to an alyze the surveillance data of chronic diseases in recent ten years Result:Three chronic diseases incidence rate was going up,male incidence rate was higher than that of female Malignant Nepolasm incident rate was first o ne, but Carebrovacular diseases increase was the fastest Diebetes Mellitus...

目的 :了解成都市 1990~ 2 0 0 0年慢性非传染性疾病发病率的变化趋势,为慢性非传染性疾病的有效干预提供科学的数据。方法:采用 EXCEL、 SAS统计分析 1990~ 2 0 0 0年慢性非传染性疾病监测数据。结果:该市 3种慢性非传染性疾病(恶性肿瘤、脑卒中、缺血性心脏病)发病率呈上升趋势,且男性高于女性,其中恶性肿瘤发病率最高,脑卒中增长最快,恶性肿瘤中以肺癌发病率最高。糖尿病发病率女性高于男性。结论:成都市慢性非传染性疾病发病率正呈上升趋势,必须加强预防控制

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The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作:对伸臂位于顶部的单层框架—筒体模型进行分析,提出了等效转动约束的概念和转动约束刚度的表达式。

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