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Background Slowly activating delayed rectifier potassium currentI_(Ks is important in therepolarization of human cardiomyocyte action potential,especially in forming andmaintaining plateau of action potential. I_ channel is combined byαandβsubunits,which are coded by KCNQ1 and KCNE1 respectively. Mutations ofhKCNQ1/hKCNE1 genes,chronic myocardial hypertrophy and chronic heartfailure will lead to dysfunction of I_ and ingenital or acquired LQTS which areimportant factor in hazardous ventricular arrhythmia such as Torsade depoints.

实验背景缓慢激活延迟整流钾电流I_(Ks是参与人心肌细胞动作电位复极,特别是平台期形成与维持的重要外向离子流。I_通道由KCNQ1基因编码的α亚单位及KCNE1基因编码的β亚单位组成。hKCNQ1/hKCNE1基因突变或慢性心肌肥厚、慢性心力衰竭等病理过程均可导致I_功能异常,引起遗传性或获得性长QT综合征,LQTS易引起尖端扭转型室性心动过速等心律失常,从而危及病人生命。

40 patients presenting gastric symptoms underwent gastric mucosa biopsy while doing gastroscopy. All samples were analyzed by Wartin-Stany dying, rapid urase test, and 13C-urea breath test respectively as well as by histological examination. The patients with the same results by WS and RUT were regarded as chronic gastritis. In this patient, we analyzed the specificity, sensitivity and accuracy of 13CUBT.

取40例因上腹部症状而行胃镜检查的患者胃窦粘膜活检,分别行Wartin-Stany银染色、快速尿素酶实验、13C尿素呼气试验(13CUBT),并同时行病理组织学诊断;将WS和RUT结果相一致且病理结果为慢性胃炎的病例入选,分析13C尿素呼气试验(13CUBT)诊断慢性胃炎幽门螺杆菌感染的特异性、敏感性、准确性。

40 patients presenting gastric symptoms underwent gastric mucosa biopsy while doing gastroscopy. All samples were analyzed by Wartin-Stany dying, rapid urase test, and 13C-urea breath test respectively as well as by histological examination. The patients with the same results by WS and RUT were regarded as chronic gastritis.

取40例因上腹部症状而行胃镜检查的患者胃窦粘膜活检,分别行Wartin-Stany银染色、快速尿素酶实验、13C尿素呼气试验(13CUBT),并同时行病理组织学诊断;将WS和RUT结果相一致且病理结果为慢性胃炎的病例入选,分析 13C尿素呼气试验(13CUBT)诊断慢性胃炎幽门螺杆菌感染的特异性、敏感性、准确性。

All samples were analyzed by Wartin-Stany dying, rapid urase test, and 13C-urea breath test respectively as well as by histological examination. The patients with the same results by WS and RUT were regarded as chronic gastritis. In this patient, we analyzed the specificity, sensitivity and accuracy of 13CUBT.

取40例因上腹部症状而行胃镜检查的患者胃窦粘膜活检,分别行Wartin-Stany银染色、快速尿素酶实验、13C尿素呼气试验(13CUBT),并同时行病理组织学诊断;将WS和RUT结果相一致且病理结果为慢性胃炎的病例入选,分析13C尿素呼气试验(13CUBT)诊断慢性胃炎幽门螺杆菌感染的特异性、敏感性、准确性。

Methods The level of serum and urinary tissue-type plasminogen activator and plasminogen activator inhibitor-1 (PAT-1) were measured in 38 patients with chronic glomerulonephritis, 28 patients with nephropathy syndrome, 36 patients with chronic renal failure and 20 healthy subjects by means of enzyme-linked immunosorbent assary. The relationship among urinary t-PA, PAI-l and serum t-PA, PAT-1, urinary protein, serum creatinine were also observed. Results Levels of serum t-PA, PAI-1 in chronic kidney diseases increased remarkably compared with control group.

选择38例慢性肾小球肾炎,28例肾病综合征,36例非透析治疗的慢性肾功能不全和20例正常对照作为研究对象,应用ELISA法检测血清和尿液中组织型纤溶酶原激活剂和纤溶酶原激活物抑制剂-1(PAI-1)的浓度,同时分析尿中t-PA和PAI-1的水平与血t-PA、PAI-1、血肌酐和24h尿蛋白总量之间相关性。

The chronic ethyl alcohol toxic dysphrenia to own health,the descendant,the family and the society causes a bigger harm,more anxious is along with the people living standard enhancement,the public relations drinks wine universally,our country chronic ethyl alcohol toxic dysphrenia disease incidence rate is increasing year by year.

慢性酒精中毒性精神障碍对自身健康、后代、家庭和社会均造成较大危害,更令人担忧的是随着人们生活水平的提高,社交性饮酒更加普遍,我国慢性酒精中毒性精神障碍的发病率在逐年增加。

Invigorating spleen and reducing fever is a kind of TCM therapeutic rue treated with Chronic colitis, Which is prescribed according to the theory of TCM and modern gastroenterological research combing with Professor Shan s clinical experience of more than forty years.

健脾清热法是单兆伟教授以中医脾胃理论及现代消化病学研究成果为依据,结合四十余年临床经验提出的治疗慢性结肠炎的方法。本文从理论和临床两个方面,对健脾清热法治疗慢性结肠炎作了较深入的探讨。

Objective: Establishing diverse models of rat chronic granulomatous inflammation to provide model preparation for the study of CGI against malignancy.

目的:为证明慢性肉芽肿性炎的抗肿瘤性,旨在摸索建立出在机体内持久保持的慢性肉芽肿性炎的动物模型,并对其抗肿瘤性进行了初步探讨研究。

It is speculated that this components feedback adjusting the this receptor\'s expression through receptor-binding with 5-HT3A receptor.3.3 Effection of Iridoids composition of Valeriana jatamansi Jones on THP1 mRNA expression of IBS rats induced by chronic stressMethods:Animals were randomly divided into 6 groups:normal group,model group, OSD group,FXT group,MSP group and Iridoids composition of Valeriana jatamansi Jones groups.

表明蜘蛛香环烯醚萜不影响色氨酸羟化酶的转录表达。3.1.3蜘蛛香环烯醚萜对5-HT受体的影响目的:探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠5-HT3受体mRNA表达的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

It is speculated that this components feedback adjusting the this receptor\'s expression through receptor-binding with 5-HT3A receptor.3.3 Effection of Iridoids composition of Valeriana jatamansi Jones on THP1 mRNA expression of IBS rats induced by chronic stressMethods:Animals were randomly divided into 6 groups:normal group,model group, OSD group,FXT group,MSP group and Iridoids composition of Valeriana jatamansi Jones groups.

表明蜘蛛香环烯醚萜不影响色氨酸羟化酶的转录表达。3.1.3蜘蛛香环烯醚萜对5-HT受体的影响目的:探讨蜘蛛香环烯醚萜对(来源:ABC论文aaaaaa网www.abclunwen.com)慢性应激所致IBS大鼠5-HT3受体mRNA表达的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

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