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Objective:in order to compare the curative effects of using lamirudine and thymosin together with using thymosin only to the paients of chronic hepatitis b.methods:we had chosen 27 medical cases of chronic hepatitis b,which were divided into two groups:15 cases asone group,and 12 cases as the other group.let group a take 100 mglamirudine orally,qd,with half a year as a period of treatment.at the same time givethe patients injections of 100 mg thymosin,qd,for a month.to group b was only takenlamirudine.alt,tbil,the indicators of the virosis of hepatitis b (hbsag,hbeag,hbv-dna)were observed as quatos.results: at the end of the treatment, the rates that groupa and group b made hbsag transform into negative were respectively 26.67% and 16.67%(p>0.05);hbeag:33.33%,8.33%;hbv-dna:53.33%,33.33%(p>0.05).conclusion:combining thymic peptide with 3tc to treat chronic type b hepatitis, thymic peptide will not only promote b-cell to mature and transformation, but also to keep the subpopulation of t-cell in immune system in balance, which can enhance the reaction of matured t-cell to the antigen or other stimulus.

目的:比较拉米夫定(3tc)与胸腺肽联用和单用拉米夫定治疗慢性乙型肝炎的疗效。方法:选择慢性乙型肝炎患者27例,分为联合组15例和拉米夫定组12例;联合组用拉米夫定100 mg,口服,qd,疗程半年,合并用胸腺肽100 mg,静滴,qd,疗程1个月。拉米夫定组单用拉米夫定。以谷丙转氨酶、血清胆红素、乙肝病毒标志物(hbsag,hbeag,hbv-dna)为观察指标,比较不同治疗方案对指标的影响。结果:治疗结束时联合组与拉米夫定组对慢性乙肝患者血清hbsag阴转率分别是26.67%和16.67%(p>0.05);hbeag阴转率分别是33.33%和8.33%(p>0.05);hbv-dna阴转率分别是53.33%和33.33%(p>0.05)。结论:胸腺肽联合3tc治疗慢乙肝,胸腺肽具有促进t淋巴细胞的成熟和转化,并维持免疫系统各t淋巴细胞亚群间的平衡作用,能增强成熟t淋巴细胞对抗原或其他刺激的反应。

The results showed that the values of CD4, CD4/CD8 were all lowered in these cases, sIL - I R increase which was even more conspicuous in deficient group, indicating that there were cytological immuno - defect and disharmoney of immunological balance. Therefore, both the T - lymphocyte subgroup and sIL-Ⅱ R can be served as indices for differentiation of sthenic and asthenic syndrome types.

结果表明,慢性肝炎患者CD_4及CD_4/CD_8值下降,CD_8及sIL—2R值上升,且虚证组较实证组更为明显,说明慢性肝炎患者存在细胞免疫功能的缺陷及免疫平衡的失调,T淋巴细胞亚群及sIL—2R可作为慢性肝炎中医虚实辨证的客观化指标之一。

Results showed:(1) The airway responsiveness of smoke control group was higher than that of normal control group, the airway responsiveness of smoke + exercise group was lower than that of smoke control group;(2) Plasma level of cortisol determined immediately after exercise was higher than that determined before exercise, no significant difference occurs between that determined next day morning after all exercise finished in contrast to that determined before exercise;(3) HE staining showed, there was severe chronic pulmonary inflammatory response in smoke control group, which was reduced in the smoke + exercise group;(4) chronic cigarette smoke downregulated the protein and mRNA expression of BKca in smooth muscles of bronchi and bronchioli, exercise increased the mRNA expression of BKca;(5) chronic cigarette smoke downregulated the protein and mRNA expression of Kv1. 5 in smooth muscles of bronchi and bronchioli, exercise increased both the protein and mRNA expression of Kv1. 5 in contrast to smoke control group in bronchioli and did not effect the expression of Kv1. 5 in bronchi;(6) chronic cigarette smoke induced upregulation of FIZZ1/RELMα in bronchial smooth muscle cells, exercise decreased these effect.

结果:(1)吸烟对照组的气道反应性明显增高,吸烟加运动应激可明显降低大鼠的气道反应性;(2)吸烟运动组运动后血浆皮质醇浓度明显高于运动前,但全部运动结束后次日晨测定的血浆皮质醇浓度与运动前无明显差异;(3)HE染色显示,吸烟对照组肺组织出现明显的慢性炎症反应,吸烟加运动应激组比吸烟对照组炎症反应轻;(4)慢性吸烟可降低大鼠大气道和小气道BKca mRNA和蛋白表达,而吸烟加运动应激可使BKca mRNA表达上调,但对小气道的蛋白表达无影响;(5)慢性吸烟可降低大鼠大气道和小气道Kv1.5蛋白和mRNA表达,在小气道吸烟加运动应激可减轻这种作用,大气道则无作用;(6)吸烟使支气管平滑肌的FIZZ1/RELMα蛋白表达明显增强,而吸烟加运动组的RELMα蛋白及mRNA均明显减弱。

Chronic gastritis is a common disease and have high incidence of a disease in china. Now, people pay much attention to the study because it is a common disease and its treatment is difficult and the state of the illness is changeable and easy carcinomatous change special chronic atrophy gastritis.

慢性胃炎是一种常见病,在我国有很高的发病率,由于慢性胃炎非常多见,它的治疗,特别是慢性萎缩性胃炎的治疗比较困难,病情反复且易发生癌变,因而对该病的研究越来越受到人们关注。

Pathological changes of mucosa from the nasal cavity, there are chronic simple rhinitis and chronic hypertrophic rhinitis, caseous rhinitis, atrophic rhinitis, etc.; Jihuan from the onset and course length, it can be divided into acute rhinitis and chronic rhinitis .

粘膜病理变化,从鼻腔,有慢性单纯性鼻炎,慢性肥厚性鼻炎,干酪性鼻炎,萎缩性鼻炎等;从一开始就和课程长度极寰,可分为急性鼻炎,慢性鼻炎分歧。

chronic filariasis,especially filarial chyluria,hemotochyluria,lymphedemais still the serious clinical problems.efforts have been made in treatment of the filariasis by researchers at home and abroad but no ideal method is available.new advance in therapeutic research has been made in recent years.in this article the advance in treatment of filariasis with physical,traditional chinese medicine and western medicine,surgery and gene therapy were discussed and the results were compared as well.

慢性丝虫病尤其是丝虫性乳糜尿、乳糜血尿、淋巴水肿等慢性疾病,迄今仍是临床上的几大难题,以往,国内外学者虽对上述疾病进行多方面治疗研究,但仍无理想的治疗方法。近年对上述疾病的治疗研究有了新的进展。本文选择性的阐述了对慢性丝虫病物理、中西药、外科手术和基因治疗等研究进展情况。分析比较了各种疗法的治疗效果。

The major etiology of cubital tunnel syndrome is chronic injury with sustained compression of ulnar nerve around elbow joint.

结论]肘部的创伤及慢性劳损可以导致肘管弓状韧带出现肥厚增生,引起尺神经卡压磨损,这是肘管综合征最常见的病因;其他病因还包括慢性骨关节炎,占位病变和先天异常;尺神经可被机械性卡压和磨损,出现慢性缺血缺氧,导致肘管综合征的发生;详细的体格检查和术前的肌电图检查是诊断肘管综合征的主要手段,在诊断时应注意该病与其他部位迟发性尺神经麻痹的鉴别。

According to the appearance of the chest radiograph in chronic bronchitis, three types were classified as increased-lung-marking type, emphysematous type, and mixed type.

本文通过对210例慢性支气管炎胸部平片的X线分析,探讨了慢性支气管炎的X线表现和分型,肺心病的早期发现,以及胸部平片对诊断慢性支气管炎的评价。

The Chronic Cardiopulmonary Disease, pulmonary hypertension is frequently encountered illness in clinic, and PAH is one of the COPD patients' most common and severe consequences in hemadynamics. It is also one of the diagnostic codes of CCD, the severity direct influence the disease's prognosis.

慢性肺心病肺动脉高压是临床多发病,而肺动脉高压是中老年慢性阻塞性肺病在血液动力学方面最多见和最严重的后果之一,也是慢性肺心病的诊断标准之一,其严重程度直接影响疾病的预后。

Results: The incidence of hepatogenous diabetes was 31.36%(53/169) in acute or chronic liver diseases.

结果:肝源性糖尿病在急、慢性肝病中的发生率为31.36%(53/169),在肝硬化中的发生率高于慢性肝炎与慢性重型肝炎,差异有显著性(P<0.05)。

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