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The age of initial attack has closely relationship among clinical reattack and the rate transfer to afebrile convulsion.

初发月龄与FC的临床表现、复发以及转变为无热惊厥等不良预后密切相关。

These include: encephalitis, subacute sclerosing panencephalitis, Guillain-Barre syndrome, febrile and afebrile convulsions, seizures, ataxia, ocular palsies, anaphylaxis, angioneurotic edema, bronchial spasms, panniculitis, vasculitis, atypical measles, thrombocytopenia, lymphadenopathy, leukocytosis, pneumonitis, Stevens-Johnson syndrome, erythema multiforme, urticaria, deafness, otitis media, retinitis, optic neuritis, rash, fever, dizziness, headache, and death.

这些疾病包括:脑炎,亚急性硬化全脑炎,Guillain-barre综合症,发热以及无热的抽搐,惊厥,非典型麻疹,血小板减少,淋巴结病,白细胞增多,肺炎, Stevens-Johnson综合症,红斑,风疹,耳聋,耳炎,视网膜炎,视神经炎,皮疹,发烧,头昏眼花,头痛以及死亡。

Objective: To study the anticonvulsive action of scorpion alcoholic extraction on phenytoin-resistant convulsive rats made by direct cortical electrical stimulation in order to investigate the mechanism of antagonizing drug-resistance of SAE.

中文摘要:目的:研究全蝎乙醇提取物(scorpion alcohol extraction,SAE)对电刺激大脑皮层点燃耐苯妥英钠大鼠惊厥模型的对抗作用,并探讨其抗耐药作用机制。

On the contrary, benzene hexachloride and several related compounds frequently

相反,六氯苯和几种有关化合物致病时,惊厥往往是损伤的第一个体征。

Serious complications include broncho pneumonia ( pneumonia involving the bronchi), asphyxia, seizures, and signs of brain damage.

严重的并发症包括支气管肺炎、窒息发作,偶致惊厥及脑损害。

Objective: To investigate the effects of Thiopental on δ-band of QPEEG in convulsant rabbits.

目的:观察硫喷妥钠对惊厥家兔脑电图δ频段的影响。

Results:The three groups of P77PMC rats which experienced 30 and less than 30 times of audiogenic seizure and the Wistar control group did not display MF sprouting in dentate gyrus, however, the group of P77PMC rats which experienced 50 times of AGS was found hippocampal MF sprouting into the inner molecular layer of dentate gyrus.

结果:在全身性强直阵挛性惊厥发作次数少于30次的P77PMC大鼠以及对照的Wistar大鼠海马内均未见到MF发芽表现;而在经历50次Ⅳ~Ⅴ级听源性惊厥发作的一组P77PMC大鼠海马内观察到了MF发芽的现象,在海马齿状回内分子层内见到Timm染色呈棕黑色颗粒异常分布的MF末梢。

Methods The compound preparation was administered intragastrically in mice, whose spontaneous activity was observed along with their tolerance of the preparation after long-term administration. The hypnotic effect of the compound was assessed by investigating the changes in the pentobarbital sodium-induced sleeping. The compound was tested for its antiseizure effect in mice with pentetrazole-induced clonic and tonic convulsion. Diazepam was used as the standard control in all experiments.

利用光电计数法观察灌胃给予复方酸枣仁油栀子油对小鼠自发活动的影响,以及长期使用药物对小鼠耐受性的影响;利用延长戊巴比妥钠睡眠时间实验和戊巴比妥钠阈下催眠剂量实验,观察复方酸枣仁油栀子油的催眠作用;利用戊四氮诱发小鼠阵挛性、强直性惊厥观察复方酸枣仁油栀子油的抗惊厥作用;本实验用地西泮进行平行对照实验,并进行了组方设计和实验。

Meanwhile, in the CA3 area of hippocampus in NS group, a small amount of N-Cadherin positive cells were visible and were slightly stained. Compared with NS group, in PTZ seizure group, N-Cadherin positive cells had a marked increase in area CA3 and dentate hilus (P.01), but they were strongly inhibited in PDTC group (P.05). There was no correlation between the expressions of N-cadherin, Timm-stained granules and between the age of rats with seizure.

同时,NS组14天和28天大鼠海马CA3区可见少量的N-Cadherin阳性细胞,着色不深;PTZ致惊组海马CA3和齿状回门区的N-Cadherin阳性细胞与NS组相比明显增多(P<0.01),PDTC预处理后相同区域内N-Cadherin阳性细胞较PTZ致惊组明显减少(P<0.05)。N-Cadherin与Timm染色颗粒的表达结果与惊厥鼠的日龄并无关联性。

Methods To establish amygdala kindling models in rats and observe the effect of dizocilpine on kindling models and its combination with general antiepileptic drugs (phenobarbital, valproate and nicardipine) at ineffective dose. The influence of dizocilpine on convulsions induced by semicarbazide in mice were also observed.

方法建立大鼠杏仁核慢性电刺激点燃模型,测定不同剂量的MK-801对点燃模型各项指标的影响,探讨MK-801与其他抗癫痫药的协同作用,用氨基脲诱发的小鼠惊厥模型测定MK-801抗惊厥作用。

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