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Serious convulsion is usually followed by cardiotoxicity induced by local anesthetics. The ratio of medial lethal dose (CD50) and median convulsant doses (LD50) is usually used to assess the comparative safety of local anesthetics.

中枢神经系统明显的神经毒性作用往往是心脏毒性产生的先兆,半数致死剂量和半数致惊厥剂量的比值能够反应局麻药的安全性。

The seizure sensitive rats were made by subcutaneous injection of a convulsant dose (10mg/kg) of KA. Normal saline , PL017 or β-FNA were infused constantly into ventral hippocampus of awakened and freely moving animals for 7 days by mini-osmotic pumps. 7 days later, all rats were given subcutaneously with subconvulsant dose of KA.

皮下注射惊厥剂量(10mg/kg)的KA制备颞叶癫癎模型的癫癎发作敏感大鼠,采用微渗透泵技术分别将生理盐水、PL017和β-FNA连续7天恒速注入清醒自由活动的上述动物的腹侧海马内。7天后皮下注射阈下剂量(5mg/kg)KA检测癫癎发作敏感性形成情况。

The epilepsy model induced by kainic acid is a dynamical model condition. 5-7 days after acute seizure episodes induced by a single systemic injection of a convulsant dose (10mg/kg) of KA the rats developed a long-lasting increase in seizure susceptibility and the characteristic histopathological features in the hippocampus similar to human TLE. So the KA model has been a well-known model to study TLE or intractable epilepsy.

颞叶癫癎红藻氨酸(kainic acid,KA)模型具有明确的动态变化过程,一次全身性给予惊厥剂量(10mg/kg)KA诱发SD大鼠急性癫癎发作后5-7天,动物开始出现癫癎发作敏感性长期增强,脑内亦发生与人类颞叶癫癎相似的神经病理、神经生化及神经分子生物学方面的改变,因此被认为是研究颞叶癫癎和难治性癫癎的理想模型之一。

Other patients who should not use the device include persons who will undergo magnetic resonance imaging or deep tissue heat treatment known as diathermy.

接受电惊厥治疗的患者不应该被植入此类装置,其他不应使用此装置的患者包括:即将接受核磁共振检查的患者和接受透热治疗的患者。

The present study determined the effect of laudanosine on the minimum alveolar concentration of halothane and the influence of different inhaled anesthetics on the plasma concentration-seizure effect relationship for laudanosine in rabbits.

本文研究了Laudanosine在家兔中的药物代谢动力学及其对家兔氟烷MAC的影响,观察了几种常用吸入麻醉剂对家兔Laudanosine致惊厥血浆阈浓度的影响。

39C ( 102f ). Illnesses that most commonly cause febrile convulsions include viral upper respiratory infections such as flu, ear infections, or roseola (a virus causing a temperature and rash).

疾病最常见的原因惊厥,包括病毒性上呼吸道感染,如感冒,耳朵感染,或roseola (一种病毒引起的温度及出疹的病征)。

The invention relates to the synthesis of N-aryl group-3-(4-Beta-D-pyran allose glycoside phenyl)-5-formyl isoxazole-4-formamide and discloses a helicid derivative which can improve the functions of a central nervous system and the preparation method thereof; wherein, the compound has good sedative, hypnotic and anti-convulsant effects and is taken in the 2000 edition Chinese Pharmacopoeia with the drug name of helicid tablets.

N-芳基-3-(4-β-D-吡喃阿洛糖苷苯基)-5-甲酰基异唑-4-甲酰胺的合成,发明公开了具有改善中枢神经系统功能的豆腐果苷类衍生物,及其制备方法。该类化合物具有良好的镇静、安眠、抗惊厥作用。目前已以药品名&神衰果素片&被收入2000年版《中国药典》。

Qingyangshenylycosides is a mixture of several related compounds derived from the root of a Traditional Chinese Medicine, Cynanchum Otophyllum. Pharmacological characterization of the compounds indicated that the drug had a significant antiepileptic and anticonvulsant activity on kindling, rat audiogenic seizures and ferrous sulfate-induced epilepsy.

青阳参总甙(Qingyangshenylycosides,QYS)是萝摩科鹅绒属植物青阳参根粉提取物,已有动物实验表明QYS对大鼠听源性惊厥(audiogenic seizure,AGS)发作、&点燃&效应以及硫酸亚铁诱导的癫痫发作具有明显的对抗作用,表现出显著的抗癫痫效应。

Patients with convulsibility epileptics were diagnosed.78% seizures was obviously decreased.59% seizures was ended.conclusion mode of management,prevention and cure on epilepsy among rural is effective in populations of ningxia.it is worth to make use of management,prevention and cure on many chronic diseases among rural areas in china.curative effect of pb is positive and has few side effects.it is cheap and convenient for application and extention among rural regions.

治疗效果:79%发作次数明显减少,59%发作终止,副作用随疗程的延长而减少。结论宁夏农村地区癫痫的防治和管理模式是有显著成效的,该防治管理模式对常见、多发慢性疾病在中国农村地区防治管理值得借鉴。苯巴比妥单药治疗惊厥性癫痫发作,疗效肯定,副作用少、价廉、方便,适合在农村贫困地区广泛应用和推广。

Laura Grabel, a professor of biology at Wesleyan, whose $800,000 research project focuses on epilepsy, has done some similar work using stem cells in mice, and said that using human stem cells would take the research one step closer to an ability to apply it in patients.

Laura Grabel是卫理公会派一名生物学教授,他的80万研究计划是有关惊厥,已经用鼠干细胞做了一些类似的工作,并且说:运用人干细胞将使该研究被用于人类的能力更进一步。

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