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Methods Rats were administered with three doses of chemical convulsant, pentylenetetrazol, 20,40 and 60 mg/kg, intraperitoneally every two days.

方法对大鼠隔日腹腔注射惊厥阈下低、中、高3个剂量(20、40、60mg/kg)的戊四氮,通过观察动物体重变化、行为表现及电生理等资料评价3个剂量的戊四氮,在模型点燃过程中产生的不同效应。

Methods Rats were administered with three doses of chemical convulsant, pentylenetetrazol, 20, 40 and 60mg/kg, intraperitoneally every two days. The bodyweight of the aminal, rats behavior and the skull electroencephalo-graphs were observed and evaluated in different groups.

对大鼠隔日腹腔注射惊厥阈下低、中、高3个剂量(20、40、60mg/kg)的戊四氮,通过观察动物体重变化、行为表现及电生理等资料评价3个剂量的戊四氮,在模型点燃过程中产生的不同效应。

This study demonstrated that KA administration in a convulsant dose could result in spontaneous recurrent seizures and permanent disturbances of behavior and cognition in old rats (P25、P60) which brains were in mature. However temporal and reversible effects occurred in rat pups (P5、P15) in immature brain.

一次给予惊厥剂量的KA可诱发脑发育成熟大鼠(P25、P60)出现自发癫痫发作,但在脑发育未成熟大鼠(P5、P15)中未见有自发癫痫发作;KA致痫对脑发育成熟大鼠造成的认知行为异常持久而不可逆,但对脑发育未成熟幼鼠认知行为的影响则持续时间短而可逆。

There is no evidence that simple febrile convulsions cause any lasting damage such as brain damage or learning difficulties.

没有任何证据表明,简单的惊厥造成任何持久的损害,如脑损伤或学习有困难的。

All of a sudden I went into convulsions and a demon came out of me screaming.

突然我陷入惊厥,一个魔鬼尖叫着从我里面出来,那是自杀的邪灵,它在我里面抓住我好长的一段时间,它走开了,那是我看过有史以来最可怕黑暗的生物。

Objective To investigate the clinical manifestation of convulsive status epilepticus associated with the outcome of children contracted this illness in order to make an effort to prevent and treat those children.

目的 探讨小儿惊厥险癫痫持续状态患者的临床特征及预后的相关因素,为有效的预防和治疗小儿CSE提供依据。

Methods: Experimental rats were injected with KA (10mg/kg, 5mg/ml) subcutaneously to make status epilepticus model. SE latter 10 day, Use subliminal dosages KA to check falling sickness paroxysm sensibility model; SE latter 10 day , Morris water maze was to evaluate cognitive function in the animals. Changing NPY adopt immunocyte chemistry method to check the rat brain inner is expressed.

本研究给Sprague-Dawley大鼠颈部皮下注射惊厥剂量的红藻氨酸(KA,10mg/kg,5mg/ml),诱发癫痫持续状态(status epilepticus,SE), 10天后,用阈下剂量的KA检测癫痫发作敏感性模型;10天后用Morris水迷宫实验检测动物学习记忆功能变化;用免疫组化技术检测动物海马CA1区CA3区NPY表达的变化。

At the beginning, the domestic and external scholars studied it on the cattle, rat, lapin, fish , pig and cat etc , the result showed that the physiological effect of Coriaria lactone was similar to that of picrotoxinin , which effected nerve system , made the muscle and respiration exited and the vascular contracted , animated the heart restraint center so lead to the animal coma , startle , spasm etc symptom .

人们很早就认识到了它的毒性,最初国内外学者分别在牛、鼠、兔、蛙、鱼、猪和猫等动物上研究证明,马桑毒素的生理效应与苦毒素的生理效应极其相似,是通过作用于神经系统,产生肌肉兴奋,呼吸亢奋,血管收缩,激活心动抑制中心等从而导致抽搐、昏迷、惊厥、癫痫等症状。

Objective: To detect changes in levels of glutamate and asparate in rat discrete brain regions which may be involved in the mechanism of seizure initiation and maintenance in soman induced seizures.

目的 :对脑内兴奋性氨基酸的变化进行定位研究。方法:应用Beckman 6300氨基酸分析仪和601黄金系统色谱工作站,对梭曼惊厥后不同时相大鼠的新鲜脑组织进行定位检测。

Phenothiazine compounds should not be used in patients receiving large doses of hypnotics, and should be used, with caution in patients with a history of convulssive disorders, since grand mal convulsions have been known to occur.

接受大剂量安眠药的患者不应使用吩噻嗪化合物,对有惊厥病史的患者应慎用,因为已知有发生过癫痫大发作。

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