惊厥

This study demonstrated that KA administration in a convulsant dose could result in spontaneous recurrent seizures and permanent disturbances of behavior and cognition in old rats (P25、P60) which brains were in mature. However temporal and reversible effects occurred in rat pups (P5、P15) in immature brain.

一次给予惊厥剂量的KA可诱发脑发育成熟大鼠（P25、P60）出现自发癫痫发作，但在脑发育未成熟大鼠（P5、P15）中未见有自发癫痫发作；KA致痫对脑发育成熟大鼠造成的认知行为异常持久而不可逆，但对脑发育未成熟幼鼠认知行为的影响则持续时间短而可逆。

The epilepsy model induced by kainic acid is a dynamical model condition. 5-7 days after acute seizure episodes induced by a single systemic injection of a convulsant dose (10mg/kg) of KA the rats developed a long-lasting increase in seizure susceptibility and the characteristic histopathological features in the hippocampus similar to human TLE. So the KA model has been a well-known model to study TLE or intractable epilepsy.

颞叶癫癎红藻氨酸（kainic acid，KA）模型具有明确的动态变化过程，一次全身性给予惊厥剂量（10mg/kg）KA诱发SD大鼠急性癫癎发作后5-7天，动物开始出现癫癎发作敏感性长期增强，脑内亦发生与人类颞叶癫癎相似的神经病理、神经生化及神经分子生物学方面的改变，因此被认为是研究颞叶癫癎和难治性癫癎的理想模型之一。

Around 3 children in every 100 have at least one febrile convulsion.

周围的3个孩子，在每100个有至少一个惊厥。

About 20% of children who have one febrile convulsion also have a close relative who has had seizures.

约有20 ％的儿童有一个谁惊厥也有近亲谁已缉获。

Objective: To study the clinical significance of serum neuron specific enolase in children with febrile convulsion.

目的：探讨热性惊厥患儿血清神经元特异性烯醇酶变化的临床意义。

Objective To study the relationship between febrile convulsion and attention deficit hyperactivity disorder.

目的探讨热性惊厥与注意缺陷多动障碍的关系。

In fact, a febrile convulsion is sometimes the first sign that the child is ill.

事实上，在惊厥，有时是首次迹象表明，儿童虐待。

Objective To study the age of initial attack febrile convulsion and its clinical significance.

目的 了解热性惊厥的初发月龄和病因、临床表现、预后等多因素的关系。

OBJECTIVE: To determine association of hyperpyretic convulsion and concentration of serumal sodium in child.

目的：了解小儿高热惊厥与血清钠浓度的关系。

Children who have one febrile convulsion, are more likely to have another during the same illness or another illness.

儿童谁有一个惊厥，更可能有另一个在同一疾病或其他疾病。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。