惊厥

Serious complications include broncho pneumonia ( pneumonia involving the bronchi), asphyxia, seizures, and signs of brain damage.

严重的并发症包括支气管肺炎、窒息发作，偶致惊厥及脑损害。

Objective: To investigate the effects of Thiopental on δ-band of QPEEG in convulsant rabbits.

目的：观察硫喷妥钠对惊厥家兔脑电图δ频段的影响。

The duration of convulsion were recorded carefully for the convulsant mice that should be marked correctly for next procedure.

空白对照组腹腹腔注射生理盐水，利多卡因各剂量组依次腹腔注射47，57，73 mg/kg的利多卡因，观察并记录各组小鼠惊厥的持续时间。

Methods Rats were administered with three doses of chemical convulsant, pentylenetetrazol, 20,40 and 60 mg/kg, intraperitoneally every two days.

方法对大鼠隔日腹腔注射惊厥阈下低、中、高3个剂量（20、40、60mg／kg）的戊四氮，通过观察动物体重变化、行为表现及电生理等资料评价3个剂量的戊四氮，在模型点燃过程中产生的不同效应。

Serious convulsion is usually followed by cardiotoxicity induced by local anesthetics. The ratio of medial lethal dose (CD50) and median convulsant doses (LD50) is usually used to assess the comparative safety of local anesthetics.

中枢神经系统明显的神经毒性作用往往是心脏毒性产生的先兆，半数致死剂量和半数致惊厥剂量的比值能够反应局麻药的安全性。

Methods Rats were administered with three doses of chemical convulsant, pentylenetetrazol, 20, 40 and 60mg/kg, intraperitoneally every two days. The bodyweight of the aminal, rats behavior and the skull electroencephalo-graphs were observed and evaluated in different groups.

对大鼠隔日腹腔注射惊厥阈下低、中、高3个剂量(20、40、60mg/kg)的戊四氮，通过观察动物体重变化、行为表现及电生理等资料评价3个剂量的戊四氮，在模型点燃过程中产生的不同效应。

Two hours later, the convulsant mice were anesthetized deeply and fixed by transcardiac perfusion for Immunohistochemistry to detect c-Fos expression.③ Comparison of neurotoxicity induced by CD50 of three agents.

将发生惊厥的小鼠妥善标记，2 h后制作冰冻冠状切片，检测神经元核蛋白c-Fos的表达，镜下计算不同区域表达c-Fos的棕黄色颗粒数目，每个颗粒代表1个神经元。

Convulsant ; picrotoxin ; penicillin ; kainic acid ; GABA A receptor

惊厥；印防己毒素；青霉素；红藻氨酸； GABAA受体

Days after a convulsant dose of KA, the seizure susceptibility were found in KA+NS group and enhanced in KA+PL017 group, whereas significantly decreased in KA+β-FNA group (p.01).β-FNA prolonged the latency and reduced the stage of seizures in dose-dependent manner.

结果显示，一次给予惊厥剂量KA后7天，KA+NS组的癫癎发作敏感性形成；MORs激动剂组（KA+PL017）动物出现癫癎发作敏感性增强；与上述两组比较，MORs拮抗剂组动物癫癎发作敏感性明显降低（p.01），β-FNA以剂量依赖方式延长癫癎发作的潜伏期、降低发作级别。

The seizure sensitive rats were made by subcutaneous injection of a convulsant dose (10mg/kg) of KA. Normal saline , PL017 or β-FNA were infused constantly into ventral hippocampus of awakened and freely moving animals for 7 days by mini-osmotic pumps. 7 days later, all rats were given subcutaneously with subconvulsant dose of KA.

皮下注射惊厥剂量（10mg/kg）的KA制备颞叶癫癎模型的癫癎发作敏感大鼠，采用微渗透泵技术分别将生理盐水、PL017和β-FNA连续7天恒速注入清醒自由活动的上述动物的腹侧海马内。7天后皮下注射阈下剂量（5mg/kg）KA检测癫癎发作敏感性形成情况。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。